A Study to Compare the Use of Fluconazole as Continuous Therapy Versus Periodic Therapy in HIV-Positive Patients With Recurrent Thrush
Public ClinicalTrials.gov record NCT00000951. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase IV Randomized Study of the Use of Fluconazole as Chronic Suppressive Therapy Versus Episodic Therapy in HIV Positive Subjects With Recurrent Oropharyngeal Candidiasis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether it is better to treat patients with fluconazole on a continuous basis to prevent thrush (yeast infection in the mouth) from coming back or to wait and treat each episode of thrush. Fluconazole is one of the most commonly prescribed drugs to treat thrush and other yeast infections. However, the number of patients with fluconazole-resistant thrush is increasing, and it is not known whether continuous or intermittent use of fluconazole leads to greater resistance. Therefore, it is important to determine the most effective treatment strategy.
Study identification
- NCT ID
- NCT00000951
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 948 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 13 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Not listed
- Primary completion
- Not listed
- Completion
- May 2002 (Actual)
- Last update posted
- Oct 29, 2021
Ends 2002
United States locations
- U.S. sites
- 53
- U.S. states
- 22
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Univ of Southern California / LA County USC Med Ctr | Los Angeles | California | 900331079 | — |
| UCLA CARE Ctr | Los Angeles | California | 90095 | — |
| Univ of California / San Diego Treatment Ctr | San Diego | California | 921036325 | — |
| San Francisco Gen Hosp | San Francisco | California | 941102859 | — |
| Univ of Colorado Health Sciences Ctr | Denver | Colorado | 80262 | — |
| Howard Univ | Washington D.C. | District of Columbia | 20059 | — |
| Institute for Clinical Research | Washington D.C. | District of Columbia | 20422 | — |
| Univ of Miami School of Medicine | Miami | Florida | 331361013 | — |
| Emory Univ | Atlanta | Georgia | 30308 | — |
| Emory Hemo Comp Evaluation Clinic / East TN Comp Hemo Ctr | Atlanta | Georgia | 303652225 | — |
| Queens Med Ctr | Honolulu | Hawaii | 96816 | — |
| Univ of Hawaii | Honolulu | Hawaii | 96816 | — |
| Northwestern Univ Med School | Chicago | Illinois | 60611 | — |
| Cook County Hosp | Chicago | Illinois | 60612 | — |
| Rush Presbyterian - Saint Luke's Med Ctr | Chicago | Illinois | 60612 | — |
| Louis A Weiss Memorial Hosp | Chicago | Illinois | 60640 | — |
| Indiana Univ Hosp | Indianapolis | Indiana | 462025250 | — |
| Division of Inf Diseases/ Indiana Univ Hosp | Indianapolis | Indiana | 46202 | — |
| Methodist Hosp of Indiana / Life Care Clinic | Indianapolis | Indiana | 46202 | — |
| Univ of Iowa Hosp and Clinic | Iowa City | Iowa | 52242 | — |
| State of MD Div of Corrections / Johns Hopkins Univ Hosp | Baltimore | Maryland | 212052196 | — |
| Johns Hopkins Hosp | Baltimore | Maryland | 21287 | — |
| Harvard (Massachusetts Gen Hosp) | Boston | Massachusetts | 02114 | — |
| Boston Med Ctr | Boston | Massachusetts | 02118 | — |
| Hennepin County Med Clinic | Minneapolis | Minnesota | 55415 | — |
| Univ of Minnesota | Minneapolis | Minnesota | 55455 | — |
| St Paul Ramsey Med Ctr | Saint Paul | Minnesota | 55101 | — |
| St Louis Regional Hosp / St Louis Regional Med Ctr | St Louis | Missouri | 63112 | — |
| Univ of Nebraska Med Ctr | Omaha | Nebraska | 681985130 | — |
| SUNY / Erie County Med Ctr at Buffalo | Buffalo | New York | 14215 | — |
| Beth Israel Med Ctr | New York | New York | 10003 | — |
| Bellevue Hosp / New York Univ Med Ctr | New York | New York | 10016 | — |
| Saint Clare's Hosp and Health Ctr | New York | New York | 10019 | — |
| Cornell Univ Med Ctr | New York | New York | 10021 | — |
| Mem Sloan - Kettering Cancer Ctr | New York | New York | 10021 | — |
| St Vincent's Hosp / Mem Sloan-Kettering Cancer Ctr | New York | New York | 10021 | — |
| Mount Sinai Med Ctr | New York | New York | 10029 | — |
| St Mary's Hosp (Univ of Rochester/Infectious Diseases) | Rochester | New York | 14642 | — |
| Univ of Rochester Medical Center | Rochester | New York | 14642 | — |
| Albert Einstein College of Medicine | The Bronx | New York | 10461 | — |
| Univ of North Carolina | Chapel Hill | North Carolina | 275997215 | — |
| Duke Univ Med Ctr | Durham | North Carolina | 27710 | — |
| Univ of Cincinnati | Cincinnati | Ohio | 452670405 | — |
| Univ of Kentucky Lexington | Cincinnati | Ohio | 45267 | — |
| Case Western Reserve Univ | Cleveland | Ohio | 44106 | — |
| MetroHealth Med Ctr | Cleveland | Ohio | 441091998 | — |
| Ohio State Univ Hosp Clinic | Columbus | Ohio | 432101228 | — |
| Philadelphia Veterans Administration Med Ctr | Philadelphia | Pennsylvania | 19104 | — |
| Univ of Pennsylvania at Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| Julio Arroyo | West Columbia | South Carolina | 29169 | — |
| Univ of Tennessee / E Tennessee Comprehensive Hemophilia Ctr | Knoxville | Tennessee | 37920 | — |
| Univ of Texas Galveston | Galveston | Texas | 775550435 | — |
| Univ of Washington | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00000951, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 29, 2021 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00000951 live on ClinicalTrials.gov.