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Completed Phase 1 Interventional

A Study of Ritonavir (an Anti-HIV Drug) in HIV-Positive Infants and Children

ClinicalTrials.gov ID: NCT00000952

Public ClinicalTrials.gov record NCT00000952. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 7:28 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase I/II Study of Ritonavir Therapy in HIV-1 Infected Infants and Children

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The study examines the safety and effectiveness of ritonavir (an anti-HIV drug), alone and in combination with other anti-HIV drugs, in HIV-positive children under 2 years of age. This study will also determine the most effective doses of ritonavir for future pediatric HIV studies. Infants infected with HIV by their mothers experience faster disease progression than adults or older children. Treatment with anti-HIV drugs administered at an early age may slow disease progression in infant populations.

Study identification

NCT ID
NCT00000952
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Enrollment
60 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
1 Month to 2 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Not listed
Primary completion
Not listed
Completion
Dec 31, 2003
Last update posted
Oct 28, 2021

Ends 2004

United States locations

U.S. sites
12
U.S. states
7
U.S. cities
8
Facility City State ZIP Site status
Long Beach Memorial Med. Ctr., Miller Children's Hosp. Long Beach California 90806
UCSD Maternal, Child, and Adolescent HIV CRS San Diego California 92103
Howard Univ. Washington DC NICHD CRS Washington D.C. District of Columbia 20060
Tulane/LSU Maternal/Child CRS New Orleans Louisiana 70112
HMS - Children's Hosp. Boston, Div. of Infectious Diseases Boston Massachusetts 02115
NYU Med. Ctr., Dept. of Medicine New York New York 10016
Nyu Ny Nichd Crs New York New York 10016
Columbia IMPAACT CRS New York New York 10032
Incarnation Children's Ctr. New York New York 10032
Harlem Hosp. Ctr. NY NICHD CRS New York New York 10037
The Children's Hosp. of Philadelphia IMPAACT CRS Philadelphia Pennsylvania 19104
St. Jude/UTHSC CRS Memphis Tennessee 38105

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00000952, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 28, 2021 · Synced Sep 5, 2026

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The complete protocol, eligibility criteria, and contact information for NCT00000952 live on ClinicalTrials.gov.

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