Comparison of Brovavir Versus Acyclovir in the Treatment of Herpes in HIV-Infected Patients
Public ClinicalTrials.gov record NCT00000953. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Evaluation of Brovavir ( BV-ara-U; SQ 32,756 ) Versus Acyclovir in the Treatment of Localized Herpes Zoster in HIV-Infected Patients
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To compare the efficacy of oral sorivudine (brovavir) and oral acyclovir for the treatment of localized herpes zoster in HIV-infected patients. HIV-infected patients are at high risk for herpesvirus infections, including varicella-zoster virus ( VZV ) infections, also called shingles. Acyclovir, an approved drug, is widely used to treat VZV infections in the HIV population. Since no data from controlled studies are available to define the role of antiviral therapy for VZV infections in HIV-infected patients, a study is needed to test the relative efficacy of brovavir, an experimental antiviral drug, versus that of acyclovir.
Study identification
- NCT ID
- NCT00000953
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 180 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Not listed
- Primary completion
- Sep 1996 (Actual)
- Completion
- Not listed
- Last update posted
- Mar 1, 2011
United States locations
- U.S. sites
- 44
- U.S. states
- 19
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Univ of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Univ of Southern California / LA County USC Med Ctr | Los Angeles | California | 900331079 | — |
| UCLA Med Ctr | Los Angeles | California | 90095 | — |
| Veterans Administration Med Ctr | Martinez | California | 94553 | — |
| Infectious Disease Med Group | Oakland | California | 94609 | — |
| San Diego Naval Hosp | San Diego | California | 92134 | — |
| Mount Zion Med Ctr | San Francisco | California | 94115 | — |
| Univ of Colorado Health Sciences Ctr | Denver | Colorado | 80262 | — |
| George Washington Univ Med Ctr | Washington D.C. | District of Columbia | 20037 | — |
| Veterans Administration Med Ctr / Community AIDS Program | Washington D.C. | District of Columbia | 20422 | — |
| Med College of Georgia | Augusta | Georgia | 30912 | — |
| Univ of Hawaii / Leahi Hosp | Honolulu | Hawaii | 96816 | — |
| Rush Presbyterian - Saint Luke's Med Ctr | Chicago | Illinois | 60612 | — |
| Johns Hopkins Hosp | Baltimore | Maryland | 21205 | — |
| Natl Institutes of Health / NIAID | Bethesda | Maryland | 20892 | — |
| Massachusetts Gen Hosp / Harvard Med School | Boston | Massachusetts | 02114 | — |
| Beth Israel Hosp | Boston | Massachusetts | 02215 | — |
| Brigham and Women's Hosp | Boston | Massachusetts | 02215 | — |
| New England Deaconess Hosp | Boston | Massachusetts | 02215 | — |
| Washington Univ | St Louis | Missouri | 63108 | — |
| Univ of New Mexico | Albuquerque | New Mexico | 87131 | — |
| Beth Israel Med Ctr | New York | New York | 10003 | — |
| Mem Sloan - Kettering Cancer Ctr | New York | New York | 10021 | — |
| Saint Luke's - Roosevelt Hosp Ctr | New York | New York | 10025 | — |
| Mount Sinai Med Ctr | New York | New York | 10029 | — |
| SUNY / Health Sciences Ctr at Stony Brook | Stony Brook | New York | 11794 | — |
| SUNY / Health Sciences Ctr at Syracuse | Syracuse | New York | 13210 | — |
| Carolinas Med Ctr | Charlotte | North Carolina | 28204 | — |
| Univ Dermatology Associates | Cincinnati | Ohio | 452670523 | — |
| Ohio State Univ / ACTU-Univ Clinic | Columbus | Ohio | 43210 | — |
| Dayton Veterans Administration Med Ctr | Dayton | Ohio | 45428 | — |
| Med College of Ohio | Toledo | Ohio | 43699 | — |
| Portland Veterans Adm Med Ctr / Rsch & Education Grp | Portland | Oregon | 972109951 | — |
| Dallas Veterans Administration Med Ctr | Dallas | Texas | 75216 | — |
| Univ of Texas, Southwestern Med Ctr of Dallas | Dallas | Texas | 75390 | — |
| Univ TX Galveston Med Branch | Galveston | Texas | 775550882 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Univ TX San Antonio Health Science Ctr | San Antonio | Texas | 782847881 | — |
| Scott and White Hosp | Temple | Texas | 76508 | — |
| Univ of Virginia Health Sciences Ctr | Charlottesville | Virginia | 22908 | — |
| Virginia Clinical Research Inc | Norfolk | Virginia | 23507 | — |
| Salem Veterans Administration Med Ctr | Salem | Virginia | 24153 | — |
| Univ of Washington | Seattle | Washington | 98104 | — |
| Great Lakes Hemophilia Foundation | Wauwatosa | Wisconsin | 53213 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00000953, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 1, 2011 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00000953 live on ClinicalTrials.gov.