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Completed Phase 2 Interventional

Comparison of Three Anti-HIV Drug Combinations in HIV-Infected Patients With No Symptoms of the Disease

ClinicalTrials.gov ID: NCT00001045

Public ClinicalTrials.gov record NCT00001045. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 23, 2026, 10:53 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Double-Blinded, Randomized Trial Comparing Zidovudine (AZT) Versus AZT Plus Didanosine (ddI) Versus AZT Plus ddI Plus Nevirapine in Asymptomatic Patients on AZT Monotherapy Who Develop a Mutation at Codon 215 of HIV Reverse Transcriptase in Serum/Plasma Viral RNA

Study identification

NCT ID
NCT00001045
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Enrollment
300 participants

Conditions and interventions

Conditions

Interventions

  • Nevirapine Drug
  • Zidovudine Drug
  • Didanosine Drug

Drug

Eligibility (public fields only)

Age range
13 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Not listed
Primary completion
Not listed
Completion
Sep 30, 1998
Last update posted
Nov 3, 2021

Ends 1998

United States locations

U.S. sites
57
U.S. states
17
U.S. cities
37
Facility City State ZIP Site status
UCLA CARE Ctr Los Angeles California 90095
Stanford at Kaiser / Kaiser Permanente Med Ctr San Francisco California 94115
Santa Clara Valley Med Ctr / AIDS Community Rsch Consortium San Jose California 951282699
San Mateo AIDS Program / Stanford Univ Stanford California 943055107
Stanford Univ Med Ctr Stanford California 943055107
Harbor UCLA Med Ctr Torrance California 90502
Univ of Colorado Health Sciences Ctr Denver Colorado 80262
Georgetown Univ Med Ctr Washington D.C. District of Columbia 20007
Children's Hosp of Washington DC Washington D.C. District of Columbia 200102916
George Washington Univ / Hershey Med Ctr Washington D.C. District of Columbia 20037
Walter Reed Army Med Ctr Washington D.C. District of Columbia 20307
Emory Univ Hosp / Pediatrics Atlanta Georgia 30306
Emory Hemo Comp Evaluation Clinic / East TN Comp Hemo Ctr Atlanta Georgia 303652225
Queens Med Ctr Honolulu Hawaii 96816
Univ of Hawaii Honolulu Hawaii 96816
Indiana Univ Hosp Indianapolis Indiana 462025250
Univ of Iowa Hosp and Clinic Iowa City Iowa 52242
State of MD Div of Corrections / Johns Hopkins Univ Hosp Baltimore Maryland 212052196
Johns Hopkins Hosp Baltimore Maryland 21287
Natl Naval Med Ctr Bethesda Maryland 208995000
Fitzsimmons Army Med Ctr Rockville Maryland 20850
Beth Israel Deaconess Med Ctr Boston Massachusetts 02215
Hennepin County Med Clinic Minneapolis Minnesota 55415
Univ of Minnesota Minneapolis Minnesota 55455
St Paul Ramsey Med Ctr Saint Paul Minnesota 55101
Univ of Nebraska Med Ctr Omaha Nebraska 681985130
Adirondack Med Ctr at Saranac Lake Albany New York 122083479
Albany Med College / Division of HIV Medicine A158 Albany New York 122083479
Mid - Hudson Care Ctr Albany New York 122083479
SUNY / Erie County Med Ctr at Buffalo Buffalo New York 14215
Bellevue Hosp / New York Univ Med Ctr New York New York 10016
Columbia Presbyterian Med Ctr New York New York 100323784
Harlem Hosp Ctr New York New York 10037
Univ of Rochester Medical Center Rochester New York 14642
SUNY / State Univ of New York Syracuse New York 13210
Bronx Municipal Hosp Ctr/Jacobi Med Ctr The Bronx New York 10461
Comprehensive Health Care Ctr / Bronx Municipal Hosp The Bronx New York 10461
Montefiore Family Health Ctr / Bronx Municipal Hosp The Bronx New York 10461
Jack Weiler Hosp / Bronx Municipal Hosp The Bronx New York 10465
Montefiore Med Ctr / Bronx Municipal Hosp The Bronx New York 10467
Montefiore Med Ctr Adolescent AIDS Program The Bronx New York 10467
North Central Bronx Hosp / Bronx Municipal Hosp The Bronx New York 10467
Univ of North Carolina Chapel Hill North Carolina 275997215
Carolinas Med Ctr Charlotte North Carolina 28203
Wake County Dept of Health Raleigh North Carolina 27610
Case Western Reserve Univ Cleveland Ohio 44106
MetroHealth Med Ctr Cleveland Ohio 441091998
Ohio State Univ Hosp Clinic Columbus Ohio 432101228
Med College of Ohio Toledo Ohio 43699
Milton S Hershey Med Ctr Hershey Pennsylvania 170330850
Univ of Pennsylvania at Philadelphia Philadelphia Pennsylvania 19104
Thomas Jefferson Univ Hosp Philadelphia Pennsylvania 191075098
Univ of Tennessee / E Tennessee Comprehensive Hemophilia Ctr Knoxville Tennessee 37920
Vanderbilt Univ Med Ctr Nashville Tennessee 37203
Univ of Texas Galveston Galveston Texas 775550435
Wilford Hall Med Ctr Lackland Air Force Base Texas 782365300
Brooke Army Med Ctr San Antonio Texas 78284

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00001045, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 3, 2021 · Synced Jul 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00001045 live on ClinicalTrials.gov.

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