Effectiveness of the Early Addition of Abacavir to an Anti-HIV Drug Combination
Public ClinicalTrials.gov record NCT00001132. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Pilot Study of Early Treatment Intensification of Antiretroviral Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to see if adding 1 drug to an anti-HIV drug combination early in treatment against HIV can lower the viral load (amount of HIV in the blood) to a level so low that it cannot be measured (undetectable). The drug that will be added to a treatment is abacavir (ABC). Many patients who take 3 anti-HIV drugs together are able to achieve very low viral loads, for example, viral loads below 50 copies/ml. However, some patients taking only 3 drugs are not able to achieve a viral load this low. Doctors hope that, by adding the drug ABC to a current treatment, a viral load below 50 copies/ml can be achieved. Doctors would like to find out if it is effective to start patients on 3 drugs and then add another drug (treatment intensification) if the treatment is not working as well as hoped.
Study identification
- NCT ID
- NCT00001132
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 80 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 13 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 31, 1999
- Primary completion
- Not listed
- Completion
- Mar 31, 2001
- Last update posted
- Sep 8, 2008
1999 – 2001
United States locations
- U.S. sites
- 29
- U.S. states
- 15
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCLA CARE Ctr | Los Angeles | California | 90095 | — |
| Willow Clinic | Menlo Park | California | 94025 | — |
| Santa Clara Valley Med Ctr / AIDS Community Rsch Consortium | San Jose | California | 951282699 | — |
| San Mateo AIDS Program / Stanford Univ | Stanford | California | 943055107 | — |
| Stanford Univ Med Ctr | Stanford | California | 943055107 | — |
| Harbor UCLA Med Ctr | Torrance | California | 90502 | — |
| Univ of Colorado Health Sciences Ctr | Denver | Colorado | 80262 | — |
| Univ of Miami School of Medicine | Miami | Florida | 331361013 | — |
| Emory Univ | Atlanta | Georgia | 30308 | — |
| Northwestern Univ Med School | Chicago | Illinois | 60611 | — |
| Cook County Hosp | Chicago | Illinois | 60612 | — |
| State of MD Div of Corrections / Johns Hopkins Univ Hosp | Baltimore | Maryland | 212052196 | — |
| Johns Hopkins Hosp | Baltimore | Maryland | 21287 | — |
| St Louis Regional Hosp / St Louis Regional Med Ctr | St Louis | Missouri | 63112 | — |
| SUNY / Erie County Med Ctr at Buffalo | Buffalo | New York | 14215 | — |
| Beth Israel Med Ctr | New York | New York | 10003 | — |
| Bellevue Hosp / New York Univ Med Ctr | New York | New York | 10016 | — |
| Aaron Diamond AIDS Rsch Ctr / Rockefeller Univ | New York | New York | 10021 | — |
| Columbia Presbyterian Med Ctr | New York | New York | 10032 | — |
| Univ of Rochester Medical Center | Rochester | New York | 14642 | — |
| Univ of North Carolina | Chapel Hill | North Carolina | 275997215 | — |
| Duke Univ Med Ctr | Durham | North Carolina | 27710 | — |
| Univ of Cincinnati | Cincinnati | Ohio | 452670405 | — |
| Philadelphia Veterans Administration Med Ctr | Philadelphia | Pennsylvania | 19104 | — |
| Univ of Pennsylvania at Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| Julio Arroyo | West Columbia | South Carolina | 29169 | — |
| Vanderbilt Univ Med Ctr | Nashville | Tennessee | 37203 | — |
| Univ of Texas, Southwestern Med Ctr of Dallas | Dallas | Texas | 75390 | — |
| Univ of Washington | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00001132, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 8, 2008 · Synced Sep 9, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00001132 live on ClinicalTrials.gov.