The Safety and Effectiveness of Zidovudine Plus Acyclovir in Patients With Early HIV Infection
Public ClinicalTrials.gov record NCT00002290. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-Center, Double-Blind Trial to Evaluate the Safety and Efficacy of Concurrent Retrovir (Zidovudine) and Zovirax (Acyclovir) Therapy in Patients With Early Symptomatic Human Immunodeficiency Virus (HIV) Infection
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This double-blind, placebo-controlled study is designed to determine the long-term safety and efficacy of concurrent oral Retrovir / Zovirax (AZT and ACV) therapy and oral AZT therapy alone, in the treatment of early symptomatic HIV infection. Efficacy will be evaluated by monitoring the incidence, severity, and time of development of opportunistic infections and other manifestations of advanced symptomatic HIV infection. The effects of the combination and single AZT therapy on immune function and viral replication will also be evaluated. Study participants will be monitored for evidence of toxicity or intolerance to concurrent AZT / ACV administration and AZT therapy alone.
Study identification
- NCT ID
- NCT00002290
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- Not listed
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Not listed
- Primary completion
- Not listed
- Completion
- Not listed
- Last update posted
- Jun 24, 2005
United States locations
- U.S. sites
- 14
- U.S. states
- 12
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Birmingham Veterans Administration Med Ctr / Univ of Alabama | Birmingham | Alabama | 35233 | — |
| Univ of Arizona / Health Science Ctr | Tucson | Arizona | 85724 | — |
| ViRx Inc | San Francisco | California | 94103 | — |
| Georgetown Univ Med Ctr / Main Hosp 4 | Washington D.C. | District of Columbia | 20007 | — |
| Veterans Administration Med Ctr | Bay Pines | Florida | 33504 | — |
| Rush Presbyterian - Saint Luke's Med Ctr | Chicago | Illinois | 60612 | — |
| Harper Hosp | Detroit | Michigan | 48201 | — |
| Univ of Pennsylvania / HIV Clinic | Philadelphia | Pennsylvania | 19104 | — |
| Vanderbilt School of Medicine | Nashville | Tennessee | 37232 | — |
| Univ TX Galveston Med Branch | Galveston | Texas | 77550 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Univ of Utah School of Medicine | Salt Lake City | Utah | 84132 | — |
| Univ of Virginia Health Sciences Ctr | Charlottesville | Virginia | 22908 | — |
| Richmond AIDS Consortium | Richmond | Virginia | 23219 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00002290, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 24, 2005 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00002290 live on ClinicalTrials.gov.