A Comparison of Lamivudine and Zidovudine, Used Alone and Together, in HIV-Infected Patients Who Have Not Used Zidovudine in the Past
Public ClinicalTrials.gov record NCT00002320. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind Multicenter Trial to Compare the Safety and Efficacy of Lamivudine (3TC; GR109714X) Monotherapy Versus Zidovudine (AZT) Monotherapy Versus 3TC Administered With AZT in the Treatment of HIV-1 Infected Patients Who Are AZT Naive (< 4 Weeks) With CD4 Cell Counts of 200-500 Cells/mm3
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To evaluate the safety and efficacy of high-dose lamivudine (3TC) alone versus zidovudine (AZT) alone versus 3TC at high and low doses in combination with AZT in HIV-1 infected patients. PER 02/27/95 AMENDMENT: To evaluate the efficacy and safety of both blinded and open-label combination therapy.
Study identification
- NCT ID
- NCT00002320
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 320 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Not listed
- Primary completion
- Not listed
- Completion
- Not listed
- Last update posted
- Dec 12, 2005
United States locations
- U.S. sites
- 18
- U.S. states
- 14
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Combat Group | Los Angeles | California | 90028 | — |
| San Diego Community Research Group | San Diego | California | 92104 | — |
| Pacific Oaks Med Group | Sherman Oaks | California | 91403 | — |
| Harbor - UCLA Med Ctr | Torrance | California | 90509 | — |
| Infectious Disease Research Institute Inc | Tampa | Florida | 33614 | — |
| AIDS Research Consortium of Atlanta | Atlanta | Georgia | 30308 | — |
| Chicago Ctr for Clinical Research | Chicago | Illinois | 60607 | — |
| Louisiana Cardiovascular Research Ctr | New Orleans | Louisiana | 70119 | — |
| CRI of New England | Brookline | Massachusetts | 02445 | — |
| Saint Luke's - Roosevelt Hosp Ctr | New York | New York | 10019 | — |
| Univ of North Carolina School of Medicine | Chapel Hill | North Carolina | 275997215 | — |
| Med College of Ohio | Toledo | Ohio | 43699 | — |
| Portland Veterans Adm Med Ctr / Rsch & Education Grp | Portland | Oregon | 97210 | — |
| Mem Hosp of Rhode Island | Pawtucket | Rhode Island | 02860 | — |
| Central Texas Med Foundation | Austin | Texas | 78751 | — |
| Nicholaos Bellos | Dallas | Texas | 75246 | — |
| Richmond AIDS Consortium | Richmond | Virginia | 23219 | — |
| Wisconsin Community - Based Research Consortium | Milwaukee | Wisconsin | 53202 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00002320, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 12, 2005 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00002320 live on ClinicalTrials.gov.