The Safety and Effectiveness of Nevirapine and Zidovudine, Given Separately and Together, in HIV-1 Infected Patients Who Have No Symptoms of the Disease
Public ClinicalTrials.gov record NCT00002324. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-Center, Placebo-Controlled, Double-Blind, Randomized Trial Comparing the Activity, Safety, and Tolerance of 1) 400 Mg Nevirapine in Combination With 500-600 Mg Zidovudine Versus Zidovudine Alone in Asymptomatic HIV-1 Infected Patients With 3-24 Months of Prior Zidovudine Therapy and 200-500 CD4 Cells/mm3 and 2) 400 Mg Nevirapine Versus Nevirapine Placebo in Asymptomatic HIV-1 Nucleoside Naive Patients With 200-500 CD4 Cells/mm3
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
PRIMARY: To compare the effect of nevirapine versus placebo alone or in combination with zidovudine (AZT) on CD4 T-cell count and percentage after 3 and 6 months of treatment. To evaluate the safety and tolerance of nevirapine alone or in combination with AZT. SECONDARY: To compare the effects of the various treatment combinations on virologic and immunologic markers.
Study identification
- NCT ID
- NCT00002324
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 250 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 13 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Not listed
- Primary completion
- Not listed
- Completion
- Not listed
- Last update posted
- Jun 23, 2005
United States locations
- U.S. sites
- 18
- U.S. states
- 14
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCSD Treatment Ctr | San Diego | California | 92103 | — |
| Saint Francis Mem Hosp | San Francisco | California | 94109 | — |
| Wilmington Hosp | Wilmington | Delaware | 19801 | — |
| Community Research Initiative of South Florida | Coral Gables | Florida | 33146 | — |
| Goodgame Med Group | Maitland | Florida | 32751 | — |
| Univ of Kansas School of Medicine | Wichita | Kansas | 67214 | — |
| Chandler Med Ctr | Lexington | Kentucky | 405360084 | — |
| Kansas City AIDS Research Consortium | Kansas City | Missouri | 641082792 | — |
| Community Research Initiative on AIDS | New York | New York | 10001 | — |
| Med College of Ohio | Toledo | Ohio | 43699 | — |
| Associates Med and Mental Health | Tulsa | Oklahoma | 74114 | — |
| Philadelphia FIGHT | Philadelphia | Pennsylvania | 19107 | — |
| Dr Alfred F Burnside Jr | Columbia | South Carolina | 29204 | — |
| Nelson-Tebedo Community Clinic | Dallas | Texas | 75219 | — |
| Houston Clinical Research Network | Houston | Texas | 77006 | — |
| Univ of Utah School of Medicine | Salt Lake City | Utah | 84132 | — |
| Infectious Disease Physicians Inc | Annandale | Virginia | 22203 | — |
| Richmond AIDS Consortium | Richmond | Virginia | 23219 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00002324, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 23, 2005 · Synced Sep 5, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00002324 live on ClinicalTrials.gov.