A Study of Zidovudine (AZT) Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Patients With Little or No Previous Treatment
Public ClinicalTrials.gov record NCT00002334. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Multicenter, Double-Blind, Phase III, Parallel Study of Zidovudine (AZT) Alone Versus AZT Plus Zalcitabine (Dideoxycytidine; ddC) Versus AZT Plus Saquinavir Mesylate (Ro 31-8959 ; HIV Proteinase Inhibitor) Versus AZT Plus ddC Plus Ro 31-8959 in Previously Untreated or Minimally Pretreated HIV-Infected Patients With CD4 Lymphocyte Counts From 50 to <= 350 Cells/mm3
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To compare, in zidovudine (AZT)-naive patients, the safety, tolerance, and efficacy of saquinavir mesylate (Ro 31-8959) alone versus AZT alone versus AZT in combination with Ro 31-8959, zalcitabine (ddC), or both. To compare various disease markers among the different regimens.
Study identification
- NCT ID
- NCT00002334
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 3,000 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Not listed
- Primary completion
- Not listed
- Completion
- Not listed
- Last update posted
- Jun 24, 2005
United States locations
- U.S. sites
- 25
- U.S. states
- 14
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Phoenix Body Positive | Phoenix | Arizona | 85016 | — |
| UCD Med Ctr | Sacramento | California | 95817 | — |
| Davies Med Ctr | San Francisco | California | 94114 | — |
| Mount Zion Med Ctr / UCSF | San Francisco | California | 94115 | — |
| Pacific Oaks Med Group | Sherman Oaks | California | 91403 | — |
| Sunnyvale Med Clinic | Sunnyvale | California | 94086 | — |
| Novum Inc | Washington D.C. | District of Columbia | 20037 | — |
| Howard Univ | Washington D.C. | District of Columbia | 20060 | — |
| Miami Veterans Administration Med Ctr | Miami | Florida | 33125 | — |
| Univ of Miami School of Medicine | Miami | Florida | 331361013 | — |
| Cook County Hosp | Chicago | Illinois | 60612 | — |
| Rush Presbyterian - Saint Luke's Med Ctr | Chicago | Illinois | 60612 | — |
| Tulane Univ Med School | New Orleans | Louisiana | 701122699 | — |
| Massachusetts Gen Hosp | Boston | Massachusetts | 02114 | — |
| HIV Wellness Ctr / Univ Med Ctr | Las Vegas | Nevada | 89102 | — |
| Beth Israel Med Ctr | New York | New York | 10003 | — |
| Harkness Pavilion | New York | New York | 10032 | — |
| Univ Hosp of Cleveland / Case Western Reserve Univ | Cleveland | Ohio | 44106 | — |
| Univ of Oklahoma Health Science / Pharmacy Practice | Oklahoma City | Oklahoma | 73117 | — |
| Novum Inc | Pittsburgh | Pennsylvania | 152063817 | — |
| Respiratory Associates | Corpus Christi | Texas | 78404 | — |
| N Texas Ctr for AIDS & Clin Rsch | Dallas | Texas | 75219 | — |
| Univ TX Galveston Med Branch | Galveston | Texas | 775550882 | — |
| Thomas Street Clinic / Baylor College of Medicine | Houston | Texas | 77009 | — |
| Univ of Washington | Seattle | Washington | 981224379 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00002334, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 24, 2005 · Synced Nov 2, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00002334 live on ClinicalTrials.gov.