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Completed Phase 3 Interventional

A Study of Zidovudine (AZT) Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Patients With Little or No Previous Treatment

ClinicalTrials.gov ID: NCT00002334

Public ClinicalTrials.gov record NCT00002334. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 8:18 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Multicenter, Double-Blind, Phase III, Parallel Study of Zidovudine (AZT) Alone Versus AZT Plus Zalcitabine (Dideoxycytidine; ddC) Versus AZT Plus Saquinavir Mesylate (Ro 31-8959 ; HIV Proteinase Inhibitor) Versus AZT Plus ddC Plus Ro 31-8959 in Previously Untreated or Minimally Pretreated HIV-Infected Patients With CD4 Lymphocyte Counts From 50 to <= 350 Cells/mm3

Study identification

NCT ID
NCT00002334
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
3,000 participants

Conditions and interventions

Conditions

Interventions

  • Saquinavir Drug
  • Zidovudine Drug
  • Zalcitabine Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Not listed
Primary completion
Not listed
Completion
Not listed
Last update posted
Jun 23, 2005

United States locations

U.S. sites
25
U.S. states
14
U.S. cities
20
Facility City State ZIP Site status
Phoenix Body Positive Phoenix Arizona 85016
UCD Med Ctr Sacramento California 95817
Davies Med Ctr San Francisco California 94114
Mount Zion Med Ctr / UCSF San Francisco California 94115
Pacific Oaks Med Group Sherman Oaks California 91403
Sunnyvale Med Clinic Sunnyvale California 94086
Novum Inc Washington D.C. District of Columbia 20037
Howard Univ Washington D.C. District of Columbia 20060
Miami Veterans Administration Med Ctr Miami Florida 33125
Univ of Miami School of Medicine Miami Florida 331361013
Cook County Hosp Chicago Illinois 60612
Rush Presbyterian - Saint Luke's Med Ctr Chicago Illinois 60612
Tulane Univ Med School New Orleans Louisiana 701122699
Massachusetts Gen Hosp Boston Massachusetts 02114
HIV Wellness Ctr / Univ Med Ctr Las Vegas Nevada 89102
Beth Israel Med Ctr New York New York 10003
Harkness Pavilion New York New York 10032
Univ Hosp of Cleveland / Case Western Reserve Univ Cleveland Ohio 44106
Univ of Oklahoma Health Science / Pharmacy Practice Oklahoma City Oklahoma 73117
Novum Inc Pittsburgh Pennsylvania 152063817
Respiratory Associates Corpus Christi Texas 78404
N Texas Ctr for AIDS & Clin Rsch Dallas Texas 75219
Univ TX Galveston Med Branch Galveston Texas 775550882
Thomas Street Clinic / Baylor College of Medicine Houston Texas 77009
Univ of Washington Seattle Washington 981224379

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00002334, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 23, 2005 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00002334 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →