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Completed Phase 3 Interventional

The Safety and Effectiveness of Lamivudine Plus Zidovudine, Used With and Without 1592U89, in HIV-1 Infected Patients Who Have Never Taken Anti-HIV Drugs

ClinicalTrials.gov ID: NCT00002389

Public ClinicalTrials.gov record NCT00002389. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 23, 2026, 8:24 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Parallel-Group, Multicenter Trial to Evaluate the Safety and Efficacy of 1592U89 in Combination With Lamivudine (3TC) and Zidovudine (ZDV) Versus 3TC/ZDV in HIV-1-Infected, Antiretroviral Therapy-Naive Subjects With CD4+ Counts >= 100 Cells/mm3

Study identification

NCT ID
NCT00002389
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Glaxo Wellcome
Industry
Enrollment
210 participants

Conditions and interventions

Conditions

Interventions

  • Abacavir sulfate Drug
  • Lamivudine Drug
  • Zidovudine Drug

Drug

Eligibility (public fields only)

Age range
13 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Not listed
Primary completion
Not listed
Completion
Not listed
Last update posted
Jun 23, 2005

United States locations

U.S. sites
13
U.S. states
10
U.S. cities
12
Facility City State ZIP Site status
East Bay AIDS Ctr Berkeley California 94705
Kraus Med Partners Los Angeles California 90036
Georgetown Univ Med Ctr Washington D.C. District of Columbia 20007
Univ of Miami Dept of Medicine Miami Florida 33136
Rush Med College / Rush Presbyterian - St Luke's Med Cen Chicago Illinois 60612
Boston Med Ctr / Evans - 556 Boston Massachusetts 021182393
Saint Michael's Med Ctr / Dept of Infectious Diseases Newark New Jersey 07102
St Vincent's Hosp and Med Ctr / AIDS Ctr New York New York 10011
Harlem Hosp New York New York 10027
Duke Univ Med Ctr / Dept of Medicine Durham North Carolina 27710
Univ of Cincinnati / Holmes Hosp Cincinnati Ohio 452670405
Dr Nicholaos Bellos Dallas Texas 75225
Baylor College of Medicine / Dept of Medicine Houston Texas 770303498

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00002389, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 23, 2005 · Synced Jul 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00002389 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →