A Study on the Safety and Effectiveness of L-756423 Plus Indinavir in HIV-Positive Patients Who Have Previously Taken Indinavir

ClinicalTrials.gov ID: NCT00002452

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Official title

A Multicenter, Open-Label, Pilot Study to Evaluate the Safety and Activity of L-756423/Indinavir Sulfate, 800/400 Mg b.i.d. in Combination With Two nRTIs in HIV-Infected Patients Who Failed an Indinavir Containing Regimen

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to see if L-756423, an anti-HIV drug, is safe to give with indinavir and if it works well at lowering the level of HIV in the blood (viral load).

Study identification

NCT ID: NCT00002452
Recruitment status: Completed
Study type: Interventional
Phase: Phase 2
Lead sponsor: Merck Sharp & Dohme LLC; Industry
Enrollment: 30 participants

Conditions and interventions

Conditions

HIV Infections

Interventions

L-756423 Drug
Indinavir sulfate Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Not listed
Primary completion: Not listed
Completion: Not listed
Last update posted: Jun 24, 2005

United States locations

U.S. sites: 8
U.S. states: 8
U.S. cities: 8

Facility	City	State	ZIP	Site status
Univ of Alabama at Birmingham	Birmingham	Alabama	352942050	—
Georgetown Univ	Washington D.C.	District of Columbia	20007	—
AIDS Research Consortium of Atlanta	Atlanta	Georgia	30308	—
Hawaii AIDS Clinical Trial Unit	Honolulu	Hawaii	96816	—
The CORE Ctr	Chicago	Illinois	60612	—
Cornell Clinical Trials Unit - Chelsea Clinic	New York	New York	10011	—
Pittsburgh Treatment Ctr / Univ of Pittsburgh	Pittsburgh	Pennsylvania	15261	—
Vanderbilt Univ Med Ctr	Nashville	Tennessee	37203	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT00002452, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jun 24, 2005 · Synced Nov 14, 2026