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Completed Phase 3 Interventional

Combination Chemotherapy With or Without Surgery in Treating Patients With Stage III Ovarian Epithelial Cancer

ClinicalTrials.gov ID: NCT00002568

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This page only displays public information reproduced from the official ClinicalTrials.gov record NCT00002568. It adds no medical advice, opinions, or eligibility judgments. The official record remains the source of truth for eligibility criteria, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 14, 2026, 4:18 PM EST

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Official title

A PHASE III RANDOMIZED STUDY OF CISPLATIN (NSC #119875) AND TAXOL (PACLITAXEL) (NSC #125973) WITH INTERVAL SECONDARY CYTOREDUCTION VERSUS CISPLATIN AND PACLITAXEL IN PATIENTS WITH SUBOPTIMAL STAGE III & IV EPITHELIAL OVARIAN CARCINOMA

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug or combining chemotherapy with surgery may kill more tumor cells. PURPOSE: Randomized phase III trial to compare the effectiveness of combination chemotherapy consisting of paclitaxel and cisplatin with or without surgery in treating patients with stage III ovarian epithelial cancer.

Study identification

NCT ID
NCT00002568
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Gynecologic Oncology Group
Network
Enrollment
470 participants

Conditions and interventions

Conditions

Interventions

Drug · Procedure

Eligibility (public fields only)

Age range
Not listed
Sex
Female
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 1994 (Type not available)
Primary completion
Dec 2004 (Actual)
Completion
Not listed
Last update posted
Jul 9, 2013

Started 1994

United States locations

U.S. sites
55
U.S. states
30
U.S. cities
50
Facility City State ZIP Site status
University of Alabama Comprehensive Cancer Center Birmingham Alabama 35294 —
CCOP - Greater Phoenix Phoenix Arizona 85006-2726 —
USC/Norris Comprehensive Cancer Center Los Angeles California 90033-0800 —
Jonsson Comprehensive Cancer Center, UCLA Los Angeles California 90095-1781 —
Chao Family Comprehensive Cancer Center Orange California 92868 —
Women's Cancer Center Palo Alto California 94304 —
Stanford University Medical Center Stanford California 94305-5408 —
University of Colorado Cancer Center Denver Colorado 80262 —
Lombardi Cancer Center, Georgetown University Washington D.C. District of Columbia 20007 —
Walter Reed Army Medical Center Washington D.C. District of Columbia 20307-5000 —
H. Lee Moffitt Cancer Center and Research Institute Tampa Florida 33612 —
Emory University Hospital - Atlanta Atlanta Georgia 30322 —
MBCCOP - Hawaii Honolulu Hawaii 96813 —
Rush-Presbyterian-St. Luke's Medical Center Chicago Illinois 60612 —
Indiana University Cancer Center Indianapolis Indiana 46202-5265 —
University of Iowa Hospitals and Clinics Iowa City Iowa 52242 —
Albert B. Chandler Medical Center, University of Kentucky Lexington Kentucky 40536-0084 —
Johns Hopkins Oncology Center Baltimore Maryland 21231 —
University of Massachusetts Memorial Medical Center Worcester Massachusetts 01655 —
CCOP - Ann Arbor Regional Ann Arbor Michigan 48106 —
Barbara Ann Karmanos Cancer Institute Detroit Michigan 48201 —
University of Minnesota Cancer Center Minneapolis Minnesota 55455 —
University of Mississippi Medical Center Jackson Mississippi 39216-4505 —
Washington University School of Medicine St Louis Missouri 63110 —
Cooper Hospital/University Medical Center Camden New Jersey 08103 —
Morristown Memorial Hospital Morristown New Jersey 07962-1956 —
Cancer Center of Albany Medical Center Albany New York 12208 —
State University of New York Health Science Center at Brooklyn Brooklyn New York 11203 —
North Shore University Hospital Manhasset New York 11030 —
Memorial Sloan-Kettering Cancer Center New York New York 10021 —
University of Rochester Cancer Center Rochester New York 14642 —
State University of New York Health Sciences Center - Stony Brook Stony Brook New York 11790-7775 —
Lineberger Comprehensive Cancer Center, UNC Chapel Hill North Carolina 27599-7295 —
Duke Comprehensive Cancer Center Durham North Carolina 27710 —
Comprehensive Cancer Center of Wake Forest University Baptist Medical Center Winston-Salem North Carolina 27157-1082 —
Barrett Cancer Center, The University Hospital Cincinnati Ohio 45219 —
Ireland Cancer Center Cleveland Ohio 44106-5065 —
Cleveland Clinic Taussig Cancer Center Cleveland Ohio 44195 —
Arthur G. James Cancer Hospital - Ohio State University Columbus Ohio 43210 —
University of Oklahoma College of Medicine Oklahoma City Oklahoma 73190 —
CCOP - Columbia River Program Portland Oregon 97213 —
Abington Memorial Hospital Abington Pennsylvania 19001 —
Milton S. Hershey Medical Center Hershey Pennsylvania 17033 —
University of Pennsylvania Cancer Center Philadelphia Pennsylvania 19104 —
Kimmel Cancer Center of Thomas Jefferson University - Philadelphia Philadelphia Pennsylvania 19107 —
Fox Chase Cancer Center Philadelphia Pennsylvania 19111 —
Medical University of South Carolina Charleston South Carolina 29425-0721 —
CCOP - Upstate Carolina Spartanburg South Carolina 29303 —
CCOP - Baptist Cancer Institute Memphis Tennessee 38117 —
Brookview Research, Inc. Nashville Tennessee 37203 —
Simmons Cancer Center - Dallas Dallas Texas 75235-9154 —
University of Texas - MD Anderson Cancer Center Houston Texas 77030-4009 —
Cancer Center, University of Virginia HSC Charlottesville Virginia 22908 —
University of Washington Medical Center Seattle Washington 98195-6043 —
Tacoma General Hospital Tacoma Washington 98405 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00002568, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 9, 2013 · Synced Nov 14, 2026

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