ClinicalTrials.gov record
Combination Chemotherapy Followed by Bone Marrow and/or Peripheral Stem Cell Transplantation in Treating Patients With Recurrent Medulloblastoma or CNS Germ Cell Tumors
ClinicalTrials.gov ID: NCT00002594
Public ClinicalTrials.gov record NCT00002594. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Dose-Intensive Melphalan and Cyclophosphamide With Autologous Bone Marrow Rescue for Recurrent Medulloblastoma and Germ Cell Tumors
Study identification
- NCT ID
- NCT00002594
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Children's Oncology Group
- Network
- Enrollment
- 31 participants
Conditions and interventions
Conditions
Interventions
- Sargramostim Biological
- autologous bone marrow transplantation Procedure
- bone marrow ablation with stem cell support Procedure
- cyclophosphamide Drug
- melphalan Drug
- peripheral blood stem cell transplantation Procedure
Biological · Procedure · Drug
Eligibility (public fields only)
- Age range
- 2 Years to 25 Years
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 31, 1994
- Primary completion
- Aug 31, 2003
- Completion
- Feb 28, 2007
- Last update posted
- Jul 23, 2014
1994 – 2007
United States locations
- U.S. sites
- 103
- U.S. states
- 35
- U.S. cities
- 83
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham Comprehensive Cancer Center | Birmingham | Alabama | 35233 | — |
| University of South Alabama Medical Center | Mobile | Alabama | 36604 | — |
| Arizona Cancer Center | Tucson | Arizona | 85724 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Rebecca and John Moores UCSD Cancer Center | La Jolla | California | 92093-0658 | — |
| Sutter Cancer Center | Sacramento | California | 95816 | — |
| University of California Davis Cancer Center | Sacramento | California | 95817 | — |
| Kaiser Permanente Medical Center/Kaiser Foundation Hospital - San Diego | San Diego | California | 92120 | — |
| Children's Hospital San Diego | San Diego | California | 92123-4282 | — |
| Kaiser Permanente Medical Center - Santa Clara | Santa Clara | California | 95051-5386 | — |
| Stanford University Medical Center | Stanford | California | 94305-5208 | — |
| Yale Comprehensive Cancer Center | New Haven | Connecticut | 06520-8028 | — |
| Walter Reed Army Medical Center | Washington D.C. | District of Columbia | 20307-5000 | — |
| Broward General Medical Center | Fort Lauderdale | Florida | 33316 | — |
| Children's Hospital of Southwest Florida | Fort Myers | Florida | 33908 | — |
| Shands Hospital and Clinics, University of Florida | Gainesville | Florida | 32610-100277 | — |
| Joe DiMaggio Children's Hospital at Memorial | Hollywood | Florida | 33021 | — |
| Nemours Children's Clinic | Jacksonville | Florida | 32207 | — |
| Sylvester Cancer Center, University of Miami | Miami | Florida | 33136 | — |
| Miami Children's Hospital | Miami | Florida | 33155-4069 | — |
| Baptist Hospital of Miami | Miami | Florida | 33176-2197 | — |
| Florida Hospital Cancer Institute | Orlando | Florida | 32804 | — |
| Nemours Children's Clinic-Orlando | Orlando | Florida | 32806 | — |
| Sacred Heart Children's Hospital | Pensacola | Florida | 32504 | — |
| All Children's Hospital | St. Petersburg | Florida | 33701 | — |
| Tampa Children's Hospital | Tampa | Florida | 33677-4227 | — |
| St. Mary's Hospital | West Palm Beach | Florida | 33407 | — |
| Children's Healthcare of Atlanta - Scottish Rite | Atlanta | Georgia | 30342 | — |
| Cancer Research Center of Hawaii | Honolulu | Hawaii | 96813 | — |
| Tripler Army Medical Center | Honolulu | Hawaii | 96859-5000 | — |
| Rush-Presbyterian-St. Luke's Medical Center | Chicago | Illinois | 60612 | — |
| Children's Memorial Hospital - Chicago | Chicago | Illinois | 60614 | — |
| Advocate Hope Children's Hospital | Oak Lawn | Illinois | 60453 | — |
| Saint Jude Midwest Affiliate | Peoria | Illinois | 61637 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160-7357 | — |
| CCOP - Wichita | Wichita | Kansas | 67214-3882 | — |
| Via Christi Regional Medical Center | Wichita | Kansas | 67214 | — |
| Wesley Medical Center | Wichita | Kansas | 67214 | — |
| MBCCOP - LSU Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Tulane University School of Medicine | New Orleans | Louisiana | 70112 | — |
| Children's Hospital of New Orleans | New Orleans | Louisiana | 70118 | — |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| Eastern Maine Medical Center | Bangor | Maine | 04401 | — |
| Maine Children's Cancer Program | Scarborough | Maine | 04074-9308 | — |
| Marlene and Stewart Greenebaum Cancer Center, University of Maryland | Baltimore | Maryland | 21201-1595 | — |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Baltimore | Maryland | 21231-2410 | — |
| Floating Hospital for Children | Boston | Massachusetts | 02111 | — |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | — |
| Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| University of Massachusetts Memorial Medical Center - University Campus | Worcester | Massachusetts | 01655 | — |
| Children's Hospital of Michigan | Detroit | Michigan | 48201 | — |
| St. John Hospital and Medical Center | Detroit | Michigan | 48236 | — |
| Hurley Medical Center | Flint | Michigan | 48503 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216-4505 | — |
| Keesler Medical Center - Keesler AFB | Keesler Air Force Base | Mississippi | 39534-2511 | — |
| University of Missouri-Columbia Hospital and Clinics | Columbia | Missouri | 65212 | — |
| Cardinal Glennon Children's Hospital | St Louis | Missouri | 63104 | — |
| Washington University Medical Center | St Louis | Missouri | 63105 | — |
| Norris Cotton Cancer Center | Lebanon | New Hampshire | 03756-0002 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| University of New Mexico Cancer Research and Treatment Center | Albuquerque | New Mexico | 87131 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263-0001 | — |
| Schneider Children's Hospital | New Hyde Park | New York | 11042 | — |
| Mount Sinai School of Medicine | New York | New York | 10029 | — |
| Beth Israel Hospital North | New York | New York | 10128 | — |
| James P. Wilmot Cancer Center | Rochester | New York | 14642 | — |
| State University of New York Health Sciences Center - Stony Brook | Stony Brook | New York | 11790-7775 | — |
| State University of New York - Upstate Medical University | Syracuse | New York | 13210 | — |
| Mission St. Joseph's Health System | Asheville | North Carolina | 28801 | — |
| Carolinas Medical Center | Charlotte | North Carolina | 28232-2861 | — |
| Presbyterian Healthcare | Charlotte | North Carolina | 28233 | — |
| Duke Comprehensive Cancer Center | Durham | North Carolina | 27710 | — |
| East Carolina University School of Medicine | Greenville | North Carolina | 27858-4354 | — |
| Comprehensive Cancer Center at Wake Forest University | Winston-Salem | North Carolina | 27157-1081 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Warren Clinic | Tulsa | Oklahoma | 74136 | — |
| Legacy Emanuel Hospital and Health Center | Portland | Oregon | 97227 | — |
| St. Christopher's Hospital for Children | Philadelphia | Pennsylvania | 19134-1095 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02818 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425-0721 | — |
| Children's Hospital of Greenville Hospital System | Greenville | South Carolina | 29605 | — |
| East Tennessee State University Cancer Center at JCMC | Johnson City | Tennessee | 37604 | — |
| St. Jude Children's Research Hospital | Memphis | Tennessee | 38105-2794 | — |
| Driscoll Children's Hospital | Corpus Christi | Texas | 78466 | — |
| Medical City Dallas Hospital | Dallas | Texas | 75230 | — |
| Simmons Cancer Center - Dallas | Dallas | Texas | 75235-9154 | — |
| Cook Children's Medical Center - Fort Worth | Fort Worth | Texas | 76104 | — |
| University of Texas Medical Branch | Galveston | Texas | 77555-0361 | — |
| Texas Children's Cancer Center | Houston | Texas | 77030-2399 | — |
| San Antonio Military Pediatric Cancer and Blood Disorders Center | Lackland Air Force Base | Texas | 78236 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78207 | — |
| Scott and White Memorial Hospital | Temple | Texas | 76508 | — |
| Vermont Cancer Center | Burlington | Vermont | 05401-3498 | — |
| Cancer Center at the University of Virginia | Charlottesville | Virginia | 22908 | — |
| Inova Fairfax Hospital | Falls Church | Virginia | 22042-3300 | — |
| Naval Medical Center, Portsmouth | Portsmouth | Virginia | 23708-5100 | — |
| Massey Cancer Center | Richmond | Virginia | 23298-0037 | — |
| Carilion Medical Center for Children | Roanoke | Virginia | 24029 | — |
| Madigan Army Medical Center | Tacoma | Washington | 98431-5000 | — |
| West Virginia University - Charleston | Charleston | West Virginia | 25302 | — |
| West Virginia University Hospitals | Morgantown | West Virginia | 26506-9300 | — |
| St. Vincent Hospital | Green Bay | Wisconsin | 54307-9070 | — |
| Midwest Children's Cancer Center | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00002594, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 23, 2014 · Synced Apr 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00002594 live on ClinicalTrials.gov.