Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic Ewing's Sarcoma or Primitive Neuroectodermal Tumor
Public ClinicalTrials.gov record NCT00002643. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
INTENSIVE THERAPY WITH GROWTH FACTOR SUPPORT FOR PATIENTS WITH EWING'S TUMOR METASTATIC AT DIAGNOSIS: A PEDIATRIC ONCOLOGY GROUP PHASE II STUDY
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Phase II trial to study the effectiveness of combination chemotherapy in treating patients with newly diagnosed metastatic Ewing's sarcoma or primitive neuroectodermal tumor. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
Study identification
- NCT ID
- NCT00002643
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 130 participants
Conditions and interventions
Conditions
Interventions
- filgrastim Biological
- amifostine trihydrate Drug
- cyclophosphamide Drug
- doxorubicin hydrochloride Drug
- etoposide Drug
- ifosfamide Drug
- topotecan hydrochloride Drug
- vincristine sulfate Drug
- conventional surgery Procedure
- low-LET cobalt-60 gamma ray therapy Radiation
- low-LET electron therapy Radiation
- low-LET photon therapy Radiation
Biological · Drug · Procedure + 1 more
Eligibility (public fields only)
- Age range
- Up to 30 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 1995 (Type not available)
- Primary completion
- Jun 2003 (Actual)
- Completion
- Not listed
- Last update posted
- Feb 1, 2013
Started 1995
United States locations
- U.S. sites
- 43
- U.S. states
- 25
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Long Beach Memorial Medical Center | Long Beach | California | 90806 | — |
| Children's Hospital Los Angeles | Los Angeles | California | 90027-0700 | — |
| Jonsson Comprehensive Cancer Center, UCLA | Los Angeles | California | 90095-1781 | — |
| Children's Hospital of Orange County | Orange | California | 92668 | — |
| UCSF Cancer Center and Cancer Research Institute | San Francisco | California | 94115-0128 | — |
| David Grant Medical Center | Travis Air Force Base | California | 94535 | — |
| Children's Hospital of Denver | Denver | Colorado | 80218 | — |
| Children's National Medical Center | Washington D.C. | District of Columbia | 20010-2970 | — |
| University of Chicago Cancer Research Center | Chicago | Illinois | 60637 | — |
| Indiana University Cancer Center | Indianapolis | Indiana | 46202-5265 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| Via Christi Regional Medical Center-Saint Francis Campus | Wichita | Kansas | 67214 | — |
| MBCCOP - LSU Medical Center | New Orleans | Louisiana | 70112 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109-0752 | — |
| CCOP - Kalamazoo | Kalamazoo | Michigan | 49007-3731 | — |
| University of Minnesota Cancer Center | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic Cancer Center | Rochester | Minnesota | 55905 | — |
| Children's Mercy Hospital - Kansas City | Kansas City | Missouri | 64108 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198-3330 | — |
| Cancer Institute of New Jersey | New Brunswick | New Jersey | 08901 | — |
| Kaplan Cancer Center | New York | New York | 10016 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10021 | — |
| Herbert Irving Comprehensive Cancer Center | New York | New York | 10032 | — |
| Memorial Mission Hospital | Asheville | North Carolina | 28801 | — |
| Lineberger Comprehensive Cancer Center, UNC | Chapel Hill | North Carolina | 27599-7295 | — |
| Veterans Affairs Medical Center - Fargo | Fargo | North Dakota | 58102 | — |
| CCOP - Merit Care Hospital | Fargo | North Dakota | 58122 | — |
| Children's Hospital Medical Center - Cincinnati | Cincinnati | Ohio | 45229-3039 | — |
| Ireland Cancer Center | Cleveland | Ohio | 44106-5065 | — |
| Children's Hospital of Columbus | Columbus | Ohio | 43205-2696 | — |
| Doernbecher Children's Hospital | Portland | Oregon | 97201-3098 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| Children's Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Vanderbilt Cancer Center | Nashville | Tennessee | 37232-6838 | — |
| Medical City Dallas Hospital | Dallas | Texas | 75230 | — |
| University of Texas - MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| San Antonio Military Pediatric Cancer and Blood Disorders Center | Lackland Air Force Base | Texas | 78236-5300 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78284 | — |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84132 | — |
| Cancer Center, University of Virginia HSC | Charlottesville | Virginia | 22908 | — |
| Children's Hospital and Regional Medical Center - Seattle | Seattle | Washington | 98105 | — |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109 | — |
| University of Wisconsin Comprehensive Cancer Center | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00002643, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 1, 2013 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00002643 live on ClinicalTrials.gov.