Radiation Therapy and Chemotherapy in Treating Children With CNS Relapse From Acute Lymphoblastic Leukemia
Public ClinicalTrials.gov record NCT00002704. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
TREATMENT OF ISOLATED CNS RELAPSE OF ACUTE LYMPHOBLASTIC LEUKEMIA -- A PEDIATRIC ONCOLOGY GROUP-WIDE PHASE II STUDY
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Phase II trial to study the effectiveness of radiation therapy following chemotherapy in treating children with CNS relapse from acute lymphoblastic leukemia. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with radiation therapy may kill more cancer cells.
Study identification
- NCT ID
- NCT00002704
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 156 participants
Conditions and interventions
Conditions
Interventions
- filgrastim Biological
- asparaginase Drug
- cyclophosphamide Drug
- daunorubicin hydrochloride Drug
- dexamethasone Drug
- etoposide Drug
- leucovorin calcium Drug
- liposomal cytarabine Drug
- mercaptopurine Drug
- mesna Drug
- methotrexate Drug
- therapeutic hydrocortisone Drug
- thiotepa Drug
- vincristine sulfate Drug
- low-LET electron therapy Radiation
- low-LET photon therapy Radiation
Biological · Drug · Radiation
Eligibility (public fields only)
- Age range
- Up to 20 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 1996 (Type not available)
- Primary completion
- Jun 2004 (Actual)
- Completion
- Not listed
- Last update posted
- Feb 1, 2013
Started 1996
United States locations
- U.S. sites
- 62
- U.S. states
- 28
- U.S. cities
- 51
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Comprehensive Cancer Center | Birmingham | Alabama | 35294 | — |
| MBCCOP - University of South Alabama | Mobile | Alabama | 36688 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| University of California San Diego Cancer Center | La Jolla | California | 92093-0658 | — |
| Lucile Packard Children's Hospital at Stanford | Palo Alto | California | 94304 | — |
| University of California Davis Medical Center | Sacramento | California | 95817 | — |
| Children's Hospital and Health Center | San Diego | California | 92123-4282 | — |
| Yale Comprehensive Cancer Center | New Haven | Connecticut | 06520-8028 | — |
| Walter Reed Army Medical Center | Washington D.C. | District of Columbia | 20307-5000 | — |
| Shands Hospital and Clinics, University of Florida | Gainesville | Florida | 32610-100277 | — |
| Sylvester Cancer Center, University of Miami | Miami | Florida | 33136 | — |
| Miami Children's Hospital | Miami | Florida | 33155 | — |
| CCOP - Florida Pediatric | Tampa | Florida | 33682-7757 | — |
| Emory University Hospital - Atlanta | Atlanta | Georgia | 30322 | — |
| Children's Memorial Hospital, Chicago | Chicago | Illinois | 60614 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160-7357 | — |
| CCOP - Wichita | Wichita | Kansas | 67214-3882 | — |
| Via Christi Regional Medical Center | Wichita | Kansas | 67214 | — |
| MBCCOP - LSU Medical Center | New Orleans | Louisiana | 70112 | — |
| Tulane University School of Medicine | New Orleans | Louisiana | 70112 | — |
| CCOP - Ochsner | New Orleans | Louisiana | 70121 | — |
| Marlene & Stewart Greenebaum Cancer Center, University of Maryland | Baltimore | Maryland | 21201 | — |
| Johns Hopkins Oncology Center | Baltimore | Maryland | 21287 | — |
| Boston Floating Hospital Infants and Children | Boston | Massachusetts | 02111 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| University of Massachusetts Memorial Medical Center | Worcester | Massachusetts | 01655 | — |
| Children's Hospital of Michigan | Detroit | Michigan | 48201 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216-4505 | — |
| Cardinal Glennon Children's Hospital | St Louis | Missouri | 63104 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| CCOP - Northern New Jersey | Hackensack | New Jersey | 07601 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263-0001 | — |
| Schneider Children's Hospital | New Hyde Park | New York | 11042 | — |
| Mount Sinai School of Medicine | New York | New York | 10029 | — |
| University of Rochester Cancer Center | Rochester | New York | 14642 | — |
| State University of New York Health Sciences Center - Stony Brook | Stony Brook | New York | 11790-9832 | — |
| State University of New York - Upstate Medical University | Syracuse | New York | 13210 | — |
| Memorial Mission Hospital | Asheville | North Carolina | 28801 | — |
| Carolinas Medical Center | Charlotte | North Carolina | 28232-2861 | — |
| Presbyterian Healthcare | Charlotte | North Carolina | 28233-3549 | — |
| Duke Comprehensive Cancer Center | Durham | North Carolina | 27710 | — |
| East Carolina University School of Medicine | Greenville | North Carolina | 27858-4354 | — |
| Comprehensive Cancer Center of Wake Forest University Baptist Medical Center | Winston-Salem | North Carolina | 27157-1082 | — |
| Oklahoma Memorial Hospital | Oklahoma City | Oklahoma | 73126-0307 | — |
| CCOP - Columbia River Program | Portland | Oregon | 97213 | — |
| St. Christopher's Hospital for Children | Philadelphia | Pennsylvania | 19134-1095 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425-0721 | — |
| Children's Hospital of Greenville Hospital System | Greenville | South Carolina | 29605 | — |
| Saint Jude Children's Research Hospital | Memphis | Tennessee | 38105-2794 | — |
| Medical City Dallas Hospital | Dallas | Texas | 75230 | — |
| Simmons Cancer Center - Dallas | Dallas | Texas | 75235-9154 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| San Antonio Military Pediatric Cancer and Blood Disorders Center | Lackland Air Force Base | Texas | 78236-5300 | — |
| MBCCOP - South Texas Pediatric | San Antonio | Texas | 78284-7810 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78284-7811 | — |
| Cancer Center, University of Virginia HSC | Charlottesville | Virginia | 22908 | — |
| Naval Medical Center, Portsmouth | Portsmouth | Virginia | 23708-2197 | — |
| Massey Cancer Center | Richmond | Virginia | 23298-0037 | — |
| West Virginia University Hospitals | Morgantown | West Virginia | 26506-9162 | — |
| Midwest Children's Cancer Center | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 8 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00002704, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 1, 2013 · Synced Oct 18, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00002704 live on ClinicalTrials.gov.