Antifungal Therapy for Fever and Neutropenia in Patients Receiving Treatment for Hematologic Cancer
Public ClinicalTrials.gov record NCT00002742. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PROSPECTIVE RANDOMIZED, DOUBLE-BLIND, COMPARATIVE, MULTICENTER STUDY TO EVALUATE EFFICACY AND SAFETY OF NYSTATIN AND AMPHOTERICIN B FOR EMPIRIC ANTIFUNGAL TREATMENT IN NEUTROPENIC PATIENTS
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Antifungal therapy with liposomal nystatin may reduce fever and neutropenia in patients undergoing treatment for hematologic cancer. It is not yet known whether liposomal nystatin is more effective than standard amphotericin B in treating patients with fever and neutropenia who are receiving chemotherapy for hematologic cancer or bone marrow transplantation for leukemia. PURPOSE: Randomized phase III trial to study the effectiveness of liposomal nystatin compared with standard amphotericin B to treat fever and neutropenia in patients receiving chemotherapy for hematologic cancer or bone marrow transplantation for leukemia.
Study identification
- NCT ID
- NCT00002742
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- Not listed
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 2 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 1996 (Type not available)
- Primary completion
- Not listed
- Completion
- Sep 2007 (Actual)
- Last update posted
- Mar 26, 2013
1996 – 2007
United States locations
- U.S. sites
- 59
- U.S. states
- 25
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Veterans Affairs Medical Center - Phoenix (Hayden) | Phoenix | Arizona | 85012 | — |
| Holt-Krock Clinic | Fort Smith | Arkansas | 72901-2418 | — |
| Arkansas Children's Hospital | Little Rock | Arkansas | 72202-3591 | — |
| Office of Rosalda Rodriguez, M.D. | Chula Vista | California | 91911 | — |
| Beckman Research Institute, City of Hope | Duarte | California | 91010 | — |
| Eisenhower Medical Center | Rancho Mirage | California | 92270 | — |
| University of Colorado Cancer Center | Denver | Colorado | 80262 | — |
| New Britain General Hospital | New Britain | Connecticut | 06050 | — |
| Vincent T. Lombardi Cancer Research Center, Georgetown University | Washington D.C. | District of Columbia | 20007 | — |
| Sylvester Cancer Center, University of Miami | Miami | Florida | 33136 | — |
| Tampa Children's Hospital | Tampa | Florida | 33677-4227 | — |
| Rush-Presbyterian-St. Luke's Medical Center | Chicago | Illinois | 60612 | — |
| St. John's Pavilion - Springfield Clinic Research Department | Springfield | Illinois | 62702 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160-7357 | — |
| Lake Charles Medical and Surgical Clinic | Lake Charles | Louisiana | 70601 | — |
| Johns Hopkins Oncology Center | Baltimore | Maryland | 21287 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| Boston University School of Medicine | Boston | Massachusetts | 02118 | — |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| United Hospital | Saint Paul | Minnesota | 55102 | — |
| Columbia Comprehensive Cancer Care Clinic | Columbia | Missouri | 65201 | — |
| University of Missouri-Columbia Hospital and Clinics | Columbia | Missouri | 65212 | — |
| Children's Mercy Hospital - Kansas City | Kansas City | Missouri | 64108 | — |
| Veterans Affairs Medical Center - Kansas City | Kansas City | Missouri | 64128 | — |
| Antibiotic Research Associates | Kansas City | Missouri | 64132 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198-3330 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Jersey Shore Cancer Center | Neptune City | New Jersey | 07753 | — |
| Riverview Medical Center | Red Bank | New Jersey | 07701 | — |
| Brooklyn Hospital Center | Brooklyn | New York | 11201 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263-0001 | — |
| Long Island Jewish Medical Center | New Hyde Park | New York | 11040 | — |
| St. Vincent's Medical Center of Richmond | Staten Island | New York | 10310 | — |
| Albert Einstein Comprehensive Cancer Center | The Bronx | New York | 10461 | — |
| Duke Comprehensive Cancer Center | Durham | North Carolina | 27710 | — |
| Brookview Research, Inc. | Winston-Salem | North Carolina | 27103 | — |
| Comprehensive Cancer Center of Wake Forest University Baptist Medical Center | Winston-Salem | North Carolina | 27157-1082 | — |
| Summa Health System | Akron | Ohio | 44312 | — |
| Ireland Cancer Center | Cleveland | Ohio | 44106-5065 | — |
| Cleveland Clinic Cancer Center | Cleveland | Ohio | 44195 | — |
| Office of Ian Baird & Mark Herbert | Columbus | Ohio | 43215 | — |
| Infectious Disease Associates of N.W. Ohio | Toledo | Ohio | 43608 | — |
| Northeast Ohio Infectious Disease Associates, Inc. | Youngstown | Ohio | 45510 | — |
| Medical Specialists, Inc. | Zanesville | Ohio | 43701 | — |
| University of Oklahoma - Department of Pharmacy Practice | Oklahoma City | Oklahoma | 73919 | — |
| University of Pennsylvania Cancer Center | Philadelphia | Pennsylvania | 19104 | — |
| Albert Einstein Cancer Center | Philadelphia | Pennsylvania | 19141 | — |
| University of Pittsburgh Cancer Institute | Pittsburgh | Pennsylvania | 15213 | — |
| University of Tennessee Medical Center at Knoxville | Knoxville | Tennessee | 37920 | — |
| Baptist Clinical Research Services | Memphis | Tennessee | 38103 | — |
| Texas Cancer Center at Brackenridge Hospital | Austin | Texas | 78701 | — |
| University of Texas Southwestern Medical School | Dallas | Texas | 75235-9032 | — |
| Infectious Disease Associates of Houston | Houston | Texas | 77030 | — |
| University of Texas - MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Wilford Hall - 59th Medical Wing | Lackland Air Force Base | Texas | 78236-5300 | — |
| South Texas Oncology and Hematology | San Antonio | Texas | 78229 | — |
| Scott and White Clinic | Temple | Texas | 76508 | — |
| Infections Limited, P.S. | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00002742, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 26, 2013 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00002742 live on ClinicalTrials.gov.