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Completed Phase 3 Interventional

Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma

ClinicalTrials.gov ID: NCT00002875

Public ClinicalTrials.gov record NCT00002875. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 5:54 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase III Prospective Randomized Study of Craniospinal RT Followed by One of Two Adjuvant Chemotherapy Regimens (CCNU, CDDP, VCR OR CPM, CDDP, VCR) for Newly-Diagnosed Average Risk MedulloblastomaMEDULLOBLASTOMA

Study identification

NCT ID
NCT00002875
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Children's Oncology Group
Network
Enrollment
421 participants

Conditions and interventions

Interventions

  • filgrastim Biological
  • cisplatin Drug
  • cyclophosphamide Drug
  • lomustine Drug
  • mesna Drug
  • vincristine sulfate Drug
  • low-LET electron therapy Radiation
  • low-LET photon therapy Radiation

Biological · Drug · Radiation

Eligibility (public fields only)

Age range
3 Years to 22 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 1996
Primary completion
Jan 31, 2006
Completion
Dec 31, 2010
Last update posted
Jul 31, 2014

1996 – 2011

United States locations

U.S. sites
36
U.S. states
24
U.S. cities
32
Facility City State ZIP Site status
Long Beach Memorial Medical Center Long Beach California 90806
Children's Hospital Los Angeles Los Angeles California 90027-0700
Jonsson Comprehensive Cancer Center, UCLA Los Angeles California 90095-1781
Children's Hospital of Orange County Orange California 92668
UCSF Cancer Center and Cancer Research Institute San Francisco California 94115-0128
Children's Hospital of Denver Denver Colorado 80218
Children's National Medical Center Washington D.C. District of Columbia 20010-2970
University of Chicago Cancer Research Center Chicago Illinois 60637
Indiana University Cancer Center Indianapolis Indiana 46202-5265
University of Iowa Hospitals and Clinics Iowa City Iowa 52242
Via Christi Regional Medical Center Wichita Kansas 67214
MBCCOP - LSU Medical Center New Orleans Louisiana 70112
University of Michigan Comprehensive Cancer Center Ann Arbor Michigan 48109-0752
University of Minnesota Cancer Center Minneapolis Minnesota 55455
Mayo Clinic Cancer Center Rochester Minnesota 55905
Children's Mercy Hospital Kansas City Missouri 64108
University of Nebraska Medical Center Omaha Nebraska 68198-3330
St. Joseph's Hospital and Medical Center Paterson New Jersey 07503
NYU School of Medicine's Kaplan Comprehensive Cancer Center New York New York 10016
Memorial Sloan-Kettering Cancer Center New York New York 10021
Herbert Irving Comprehensive Cancer Center New York New York 10032
Lineberger Comprehensive Cancer Center, UNC Chapel Hill North Carolina 27599-7295
Children's Hospital Medical Center - Cincinnati Cincinnati Ohio 45229-3039
Ireland Cancer Center Cleveland Ohio 44106-5065
Children's Hospital of Columbus Columbus Ohio 43205-2696
Doernbecher Children's Hospital Portland Oregon 97201-3098
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104
Children's Hospital of Pittsburgh Pittsburgh Pennsylvania 15213
Saint Jude Children's Research Hospital Memphis Tennessee 38105-2794
Vanderbilt Cancer Center Nashville Tennessee 37232-6838
University of Texas - MD Anderson Cancer Center Houston Texas 77030
Huntsman Cancer Institute Salt Lake City Utah 84132
Cancer Center, University of Virginia HSC Charlottesville Virginia 22908
Children's Hospital and Regional Medical Center - Seattle Seattle Washington 98105
Fred Hutchinson Cancer Research Center Seattle Washington 98109
University of Wisconsin Comprehensive Cancer Center Madison Wisconsin 53792

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00002875, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 31, 2014 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00002875 live on ClinicalTrials.gov.

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