ClinicalTrials.gov record
Estrogen Replacement Therapy in Treating Women With Early-Stage Endometrial Cancer
ClinicalTrials.gov ID: NCT00002976
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This page only displays public information reproduced from the official ClinicalTrials.gov record NCT00002976. It adds no medical advice, opinions, or eligibility judgments. The official record remains the source of truth for eligibility criteria, enrollment, and contact information.
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Official title
A Randomized Double-Blinded Trial of Estrogen Replacement Therapy Versus Placebo in Women With Stage I or II Endometrial Adenocarcinoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Estrogen replacement therapy may improve quality-of-life in postmenopausal women with endometrial cancer. It is not yet known whether estrogen replacement therapy will affect cancer recurrence. PURPOSE: Randomized double-blinded phase III trial to determine the effectiveness of estrogen replacement therapy in treating women who have stage I or stage II endometrial cancer.
Study identification
- NCT ID
- NCT00002976
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 2,108 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 1997 (Type not available)
- Primary completion
- Jul 2006 (Actual)
- Completion
- Not listed
- Last update posted
- Apr 11, 2013
Started 1997
United States locations
- U.S. sites
- 149
- U.S. states
- 40
- U.S. cities
- 102
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham Comprehensive Cancer Center | Birmingham | Alabama | 35294-3300 | — |
| MBCCOP - Gulf Coast | Mobile | Alabama | 36688 | — |
| CCOP - Greater Phoenix | Phoenix | Arizona | 85006-2726 | — |
| Veterans Affairs Medical Center - Phoenix (Carl T. Hayden) | Phoenix | Arizona | 85012 | — |
| Veterans Affairs Medical Center - Tucson | Tucson | Arizona | 85723 | — |
| Arizona Cancer Center | Tucson | Arizona | 85724 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Veterans Affairs Medical Center - Little Rock (McClellan) | Little Rock | Arkansas | 72205 | — |
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010 | — |
| USC/Norris Comprehensive Cancer Center and Hospital | Los Angeles | California | 90033-0804 | — |
| Veterans Affairs Medical Center - West Los Angeles | Los Angeles | California | 90073 | — |
| Jonsson Comprehensive Cancer Center, UCLA | Los Angeles | California | 90095-1781 | — |
| Community Hospital of Los Gatos | Los Gatos | California | 95032 | — |
| Veterans Affairs Outpatient Clinic - Martinez | Martinez | California | 94553 | — |
| CCOP - Bay Area Tumor Institute | Oakland | California | 94609-3305 | — |
| Chao Family Comprehensive Cancer Center | Orange | California | 92868 | — |
| University of California Davis Medical Center | Sacramento | California | 95817 | — |
| CCOP - Santa Rosa Memorial Hospital | Santa Rosa | California | 95403 | — |
| David Grant Medical Center | Travis Air Force Base | California | 94535 | — |
| University of Colorado Cancer Center | Denver | Colorado | 80010 | — |
| Veterans Affairs Medical Center - Denver | Denver | Colorado | 80220 | — |
| Not listed | New Britain | Connecticut | 06052 | — |
| MBCCOP-Howard University Cancer Center | Washington D.C. | District of Columbia | 20060 | — |
| Walter Reed Army Medical Center | Washington D.C. | District of Columbia | 20307-5001 | — |
| Mayo Clinic | Jacksonville | Florida | 32224 | — |
| Sacred Heart Hospital of Pensacola | Pensacola | Florida | 32504 | — |
| Tampa Bay Cancer Consortium | St. Petersburg | Florida | 33701 | — |
| H. Lee Moffitt Cancer Center and Research Institute | Tampa | Florida | 33612-9497 | — |
| CCOP - Atlanta Regional | Atlanta | Georgia | 30342-1701 | — |
| Dwight David Eisenhower Army Medical Center | Fort Gordon | Georgia | 30905-5650 | — |
| Medical College of Georgia Comprehensive Cancer Center | Savannah | Georgia | 31403-3089 | — |
| Cancer Research Center of Hawaii | Honolulu | Hawaii | 96813-2424 | — |
| Tripler Army Medical Center | Honolulu | Hawaii | 96859-5000 | — |
| Robert H. Lurie Comprehensive Cancer Center, Northwestern University | Chicago | Illinois | 60611-3013 | — |
| MBCCOP - University of Illinois at Chicago | Chicago | Illinois | 60612-7323 | — |
| Veterans Affairs Medical Center - Chicago (Westside Hospital) | Chicago | Illinois | 60612 | — |
| University of Chicago Cancer Research Center | Chicago | Illinois | 60637-1470 | — |
| CCOP - Central Illinois | Decatur | Illinois | 62526 | — |
| Veterans Affairs Medical Center - Hines (Hines Junior VA Hospital) | Hines | Illinois | 60141 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| CCOP - Carle Cancer Center | Urbana | Illinois | 61801 | — |
| Indiana University Cancer Center | Indianapolis | Indiana | 46202-5289 | — |
| CCOP - Iowa Oncology Research Association | Des Moines | Iowa | 50309-1016 | — |
| Holden Comprehensive Cancer Center | Iowa City | Iowa | 52242-1009 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160-7390 | — |
| CCOP - Wichita | Wichita | Kansas | 67214-3882 | — |
| Veterans Affairs Medical Center - Wichita | Wichita | Kansas | 67218 | — |
| Veterans Affairs Medical Center - Lexington | Lexington | Kentucky | 40502-2236 | — |
| Albert B. Chandler Medical Center, University of Kentucky | Lexington | Kentucky | 40536-0084 | — |
| Earl K. Long Medical Center | Baton Rouge | Louisiana | 70805 | — |
| MBCCOP - LSU Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Tulane University School of Medicine | New Orleans | Louisiana | 70112 | — |
| Ochsner Clinic | New Orleans | Louisiana | 70121 | — |
| Louisiana State University Health Sciences Center - Shreveport | Shreveport | Louisiana | 71130-3932 | — |
| Veterans Affairs Medical Center - Shreveport | Shreveport | Louisiana | 71130 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| Veterans Affairs Medical Center - Boston (Jamaica Plain) | Jamaica Plain | Massachusetts | 02130 | — |
| Veterans Affairs Medical Center - Ann Arbor | Ann Arbor | Michigan | 48105 | — |
| CCOP - Ann Arbor Regional | Ann Arbor | Michigan | 48106 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109-0912 | — |
| Veterans Affairs Medical Center - Detroit | Detroit | Michigan | 48201-1932 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Butterworth Hospital | Grand Rapids | Michigan | 49503 | — |
| CCOP - Grand Rapids Clinical Oncology Program | Grand Rapids | Michigan | 49503 | — |
| CCOP - Kalamazoo | Kalamazoo | Michigan | 49007-3731 | — |
| CCOP - Beaumont | Royal Oak | Michigan | 48073-6769 | — |
| Providence Hospital - Southfield | Southfield | Michigan | 48075-9975 | — |
| CCOP - Duluth | Duluth | Minnesota | 55805 | — |
| University of Minnesota Cancer Center | Minneapolis | Minnesota | 55455 | — |
| Veterans Affairs Medical Center - Biloxi | Biloxi | Mississippi | 39531-2410 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216-4505 | — |
| Veterans Affairs Medical Center - Jackson | Jackson | Mississippi | 39216 | — |
| Keesler Medical Center - Keesler AFB | Keesler Air Force Base | Mississippi | 39534-2576 | — |
| Ellis Fischel Cancer Center - Columbia | Columbia | Missouri | 65203 | — |
| Veterans Affairs Medical Center - Kansas City | Kansas City | Missouri | 64128 | — |
| CCOP - Kansas City | Kansas City | Missouri | 64131 | — |
| CCOP - Cancer Research for the Ozarks | Springfield | Missouri | 65807 | — |
| St. Louis University Health Sciences Center | St Louis | Missouri | 63110 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Department of OB-GYN | St Louis | Missouri | 63117 | — |
| CCOP - St. Louis-Cape Girardeau | St Louis | Missouri | 63141 | — |
| CCOP - Montana Cancer Consortium | Billings | Montana | 59101 | — |
| CCOP - Missouri Valley Cancer Consortium | Omaha | Nebraska | 68106 | — |
| Methodist Cancer Center - Omaha | Omaha | Nebraska | 68114 | — |
| Cooper Hospital/University Medical Center | Camden | New Jersey | 08103-1489 | — |
| Morristown Memorial Hospital | Morristown | New Jersey | 07962-1956 | — |
| Veterans Affairs Medical Center - Albuquerque | Albuquerque | New Mexico | 87108-5138 | — |
| MBCCOP - University of New Mexico HSC | Albuquerque | New Mexico | 87131 | — |
| Cancer Center of Albany Medical Center | Albany | New York | 12208 | — |
| State University of New York Health Science Center at Brooklyn | Brooklyn | New York | 11203 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10021 | — |
| Herbert Irving Comprehensive Cancer Center | New York | New York | 10032 | — |
| University of Rochester Medical Center | Rochester | New York | 14642 | — |
| State University of New York Health Sciences Center - Stony Brook | Stony Brook | New York | 11794-8091 | — |
| Crouse Hospital | Syracuse | New York | 13210 | — |
| Lineberger Comprehensive Cancer Center, UNC | Chapel Hill | North Carolina | 27599-7295 | — |
| Duke Comprehensive Cancer Center | Durham | North Carolina | 27710 | — |
| Southern Pines Women's Health Center | Southern Pines | North Carolina | 28388-0749 | — |
| CCOP - Southeast Cancer Control Consortium | Winston-Salem | North Carolina | 27104-4241 | — |
| Comprehensive Cancer Center at Wake Forest University | Winston-Salem | North Carolina | 27157-1065 | — |
| University of Tennessee Cancer Institute | Winston-Salem | North Carolina | 27157-1065 | — |
| Veterans Affairs Medical Center - Cincinnati | Cincinnati | Ohio | 45220-2288 | — |
| Barrett Cancer Center | Cincinnati | Ohio | 45267-0501 | — |
| Ireland Cancer Center | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | 44195-9001 | — |
| CCOP - Columbus | Columbus | Ohio | 43206 | — |
| Arthur G. James Cancer Hospital - Ohio State University | Columbus | Ohio | 43210-1240 | — |
| Veterans Affairs Medical Center - Dayton | Dayton | Ohio | 45428 | — |
| CCOP - Dayton | Kettering | Ohio | 45429 | — |
| Oklahoma Medical Research Foundation | Oklahoma City | Oklahoma | 73104 | — |
| Veterans Affairs Medical Center - Oklahoma City | Oklahoma City | Oklahoma | 73104 | — |
| University of Oklahoma College of Medicine | Oklahoma City | Oklahoma | 73190 | — |
| Veterans Affairs Medical Center - Portland | Portland | Oregon | 97207 | — |
| Good Samaritan Hospital Comprehensive Cancer Center | Portland | Oregon | 97210 | — |
| CCOP - Columbia River Program | Portland | Oregon | 97225 | — |
| OHSU Cancer Institute | Portland | Oregon | 97239 | — |
| Abington Memorial Hospital | Abington | Pennsylvania | 19001-3788 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| CCOP - MainLine Health | Wynnewood | Pennsylvania | 19096 | — |
| Veterans Affairs Medical Center - Charleston | Charleston | South Carolina | 29401-5799 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425-0721 | — |
| CCOP - Greenville | Greenville | South Carolina | 29615 | — |
| CCOP - Upstate Carolina | Spartanburg | South Carolina | 29303 | — |
| CCOP - Sioux Community Cancer Consortium | Sioux Falls | South Dakota | 57104 | — |
| Baptist Regional Cancer Center - Knoxville | Knoxville | Tennessee | 37901 | — |
| University of Tennessee Medical Center at Knoxville | Knoxville | Tennessee | 37920 | — |
| Brookview Research, Inc. | Nashville | Tennessee | 37203 | — |
| Brooke Army Medical Center | Fort Sam Houston | Texas | 78234-6200 | — |
| University of Texas Medical Branch | Galveston | Texas | 77555-0587 | — |
| CCOP - M.D. Anderson Research Base | Houston | Texas | 77030-4009 | — |
| Covenant Health System | Lubbock | Texas | 79410 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78284-7845 | — |
| Veterans Affairs Medical Center - San Antonio (Murphy) | San Antonio | Texas | 78284 | — |
| Veterans Affairs Medical Center - Temple | Temple | Texas | 76504 | — |
| CCOP - Scott and White Hospital | Temple | Texas | 76508 | — |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112-5550 | — |
| Veterans Affairs Medical Center - Salt Lake City | Salt Lake City | Utah | 84148 | — |
| Fletcher Allen Health Care - Medical Center Campus | Burlington | Vermont | 05401 | — |
| Cancer Center at the University of Virginia | Charlottesville | Virginia | 22908 | — |
| Eastern Virginia Medical School | Norfolk | Virginia | 23510-1115 | — |
| Massey Cancer Center | Richmond | Virginia | 23298-0037 | — |
| University of Virginia at Roanoke | Roanoke | Virginia | 24013 | — |
| CCOP - Virginia Mason Research Center | Seattle | Washington | 98101 | — |
| Swedish Cancer Institute | Seattle | Washington | 98104 | — |
| Veterans Affairs Medical Center - Seattle | Seattle | Washington | 98108 | — |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109-1024 | — |
| CCOP - Northwest | Tacoma | Washington | 98405-0986 | — |
| Madigan Army Medical Center | Tacoma | Washington | 98431-5000 | — |
| CCOP - St. Vincent Hospital Cancer Center, Green Bay | Green Bay | Wisconsin | 54301 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00002976, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 11, 2013 · Synced Nov 14, 2026
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