ClinicalTrials.gov record
Combination Chemotherapy With or Without Interleukin-2 and Interferon Alfa in Treating Patients With Metastatic Melanoma
ClinicalTrials.gov ID: NCT00003027
Public ClinicalTrials.gov record NCT00003027. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Phase III Trial of Concurrent Biochemotherapy With Cisplatin, Vinblastine, Dacarbazine, IL-2 and Interferon A-2B Versus Cisplatin, Vinblastine, Dacarbazine Alone in Patients With Metastatic Malignant Melanoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Interleukin-2 may stimulate a person's white blood cells to kill melanoma cells. Interferon alfa may interfere with the growth of tumor cells. It is not yet known whether combination chemotherapy plus interleukin-2 and interferon alfa is more effective than combination chemotherapy alone for metastatic melanoma. PURPOSE: Randomized phase III trial to compare combination chemotherapy with or without interleukin-2 and interferon alfa in treating patients who have metastatic melanoma that cannot be treated by surgery.
Study identification
- NCT ID
- NCT00003027
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 482 participants
Conditions and interventions
Conditions
Interventions
- aldesleukin Biological
- filgrastim Biological
- recombinant interferon alfa Biological
- cisplatin Drug
- dacarbazine Drug
- vinblastine Drug
Biological · Drug
Eligibility (public fields only)
- Age range
- 18 Years to 120 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 12, 1997
- Primary completion
- Jun 30, 2007
- Completion
- Not listed
- Last update posted
- Jun 21, 2023
Started 1997
United States locations
- U.S. sites
- 94
- U.S. states
- 27
- U.S. cities
- 64
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| MBCCOP - Gulf Coast | Mobile | Alabama | 36688 | — |
| CCOP - Greater Phoenix | Phoenix | Arizona | 85006-2726 | — |
| Veterans Affairs Medical Center - Phoenix (Carl T. Hayden) | Phoenix | Arizona | 85012 | — |
| Veterans Affairs Medical Center - Tucson | Tucson | Arizona | 85723 | — |
| Arizona Cancer Center | Tucson | Arizona | 85724 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Veterans Affairs Medical Center - Little Rock (McClellan) | Little Rock | Arkansas | 72205 | — |
| Cancer Center and Beckman Research Institute, City of Hope | Duarte | California | 91010-3000 | — |
| USC/Norris Comprehensive Cancer Center and Hospital | Los Angeles | California | 90033-0804 | — |
| Veterans Affairs Medical Center - West Los Angeles | Los Angeles | California | 90073 | — |
| Jonsson Comprehensive Cancer Center, UCLA | Los Angeles | California | 90095-1781 | — |
| Veterans Affairs Outpatient Clinic - Martinez | Martinez | California | 94553 | — |
| CCOP - Bay Area Tumor Institute | Oakland | California | 94609-3305 | — |
| Chao Family Comprehensive Cancer Center | Orange | California | 92868 | — |
| University of California Davis Medical Center | Sacramento | California | 95817 | — |
| UCSF Cancer Center and Cancer Research Institute | San Francisco | California | 94143-0128 | — |
| CCOP - Santa Rosa Memorial Hospital | Santa Rosa | California | 95403 | — |
| David Grant Medical Center | Travis Air Force Base | California | 94535 | — |
| University of Colorado Cancer Center | Denver | Colorado | 80010 | — |
| Veterans Affairs Medical Center - Denver | Denver | Colorado | 80220 | — |
| CCOP - Atlanta Regional | Atlanta | Georgia | 30342-1701 | — |
| Dwight David Eisenhower Army Medical Center | Fort Gordon | Georgia | 30905-5650 | — |
| Cancer Research Center of Hawaii | Honolulu | Hawaii | 96813-2424 | — |
| MBCCOP - University of Illinois at Chicago | Chicago | Illinois | 60612-7323 | — |
| Veterans Affairs Medical Center - Chicago (Westside Hospital) | Chicago | Illinois | 60612 | — |
| CCOP - Central Illinois | Decatur | Illinois | 62526 | — |
| Veterans Affairs Medical Center - Hines (Hines Junior VA Hospital) | Hines | Illinois | 60141 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160-7353 | — |
| CCOP - Wichita | Wichita | Kansas | 67214-3882 | — |
| Veterans Affairs Medical Center - Wichita | Wichita | Kansas | 67218 | — |
| Veterans Affairs Medical Center - Lexington | Lexington | Kentucky | 40502-2236 | — |
| Albert B. Chandler Medical Center, University of Kentucky | Lexington | Kentucky | 40536-0084 | — |
| MBCCOP - LSU Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Tulane University School of Medicine | New Orleans | Louisiana | 70112 | — |
| Louisiana State University Health Sciences Center - Shreveport | Shreveport | Louisiana | 71130-3932 | — |
| Veterans Affairs Medical Center - Shreveport | Shreveport | Louisiana | 71130 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| Veterans Affairs Medical Center - Boston (Jamaica Plain) | Jamaica Plain | Massachusetts | 02130 | — |
| Veterans Affairs Medical Center - Ann Arbor | Ann Arbor | Michigan | 48105 | — |
| CCOP - Ann Arbor Regional | Ann Arbor | Michigan | 48106 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109-0912 | — |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201-1379 | — |
| Veterans Affairs Medical Center - Detroit | Detroit | Michigan | 48201-1932 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Providence Hospital - Southfield | Southfield | Michigan | 48075-9975 | — |
| CCOP - Duluth | Duluth | Minnesota | 55805 | — |
| Veterans Affairs Medical Center - Biloxi | Biloxi | Mississippi | 39531-2410 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216-4505 | — |
| Veterans Affairs Medical Center - Jackson | Jackson | Mississippi | 39216 | — |
| Keesler Medical Center - Keesler AFB | Keesler Air Force Base | Mississippi | 39534-2576 | — |
| Veterans Affairs Medical Center - Kansas City | Kansas City | Missouri | 64128 | — |
| CCOP - Kansas City | Kansas City | Missouri | 64131 | — |
| CCOP - Cancer Research for the Ozarks | Springfield | Missouri | 65807 | — |
| St. Louis University Health Sciences Center | St Louis | Missouri | 63110 | — |
| CCOP - St. Louis-Cape Girardeau | St Louis | Missouri | 63141 | — |
| CCOP - Montana Cancer Consortium | Billings | Montana | 59101 | — |
| Veterans Affairs Medical Center - Albuquerque | Albuquerque | New Mexico | 87108-5138 | — |
| MBCCOP - University of New Mexico HSC | Albuquerque | New Mexico | 87131 | — |
| Veterans Affairs Medical Center - Albany | Albany | New York | 12208 | — |
| Herbert Irving Comprehensive Cancer Center | New York | New York | 10032 | — |
| University of Rochester Medical Center | Rochester | New York | 14642 | — |
| CCOP - Southeast Cancer Control Consortium | Winston-Salem | North Carolina | 27104-4241 | — |
| Veterans Affairs Medical Center - Cincinnati | Cincinnati | Ohio | 45220-2288 | — |
| Barrett Cancer Center, The University Hospital | Cincinnati | Ohio | 45267-0501 | — |
| Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | 44195 | — |
| CCOP - Columbus | Columbus | Ohio | 43206 | — |
| Veterans Affairs Medical Center - Dayton | Dayton | Ohio | 45428 | — |
| CCOP - Dayton | Kettering | Ohio | 45429 | — |
| CCOP - Toledo Community Hospital Oncology Program | Toledo | Ohio | 43623-3456 | — |
| Oklahoma Medical Research Foundation | Oklahoma City | Oklahoma | 73104 | — |
| Veterans Affairs Medical Center - Oklahoma City | Oklahoma City | Oklahoma | 73104 | — |
| Veterans Affairs Medical Center - Portland | Portland | Oregon | 97207 | — |
| CCOP - Columbia River Program | Portland | Oregon | 97225 | — |
| OHSU Cancer Institute | Portland | Oregon | 97239 | — |
| Veterans Affairs Medical Center - Charleston | Charleston | South Carolina | 29401-5799 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425-0721 | — |
| CCOP - Greenville | Greenville | South Carolina | 29615 | — |
| CCOP - Upstate Carolina | Spartanburg | South Carolina | 29303 | — |
| Simmons Cancer Center - Dallas | Dallas | Texas | 75235-8852 | — |
| Brooke Army Medical Center | Fort Sam Houston | Texas | 78234-6200 | — |
| University of Texas Medical Branch | Galveston | Texas | 77555-0565 | — |
| Veterans Affairs Medical Center - Houston | Houston | Texas | 77030 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78284-7845 | — |
| Veterans Affairs Medical Center - San Antonio (Murphy) | San Antonio | Texas | 78284 | — |
| Veterans Affairs Medical Center - Temple | Temple | Texas | 76504 | — |
| CCOP - Scott and White Hospital | Temple | Texas | 76508 | — |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112-5550 | — |
| Veterans Affairs Medical Center - Salt Lake City | Salt Lake City | Utah | 84148 | — |
| CCOP - Virginia Mason Research Center | Seattle | Washington | 98101 | — |
| Swedish Cancer Institute | Seattle | Washington | 98104 | — |
| Veterans Affairs Medical Center - Seattle | Seattle | Washington | 98108 | — |
| CCOP - Northwest | Tacoma | Washington | 98405-0986 | — |
| Madigan Army Medical Center | Tacoma | Washington | 98431-5048 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00003027, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 21, 2023 · Synced Sep 25, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00003027 live on ClinicalTrials.gov.