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Completed Phase 3 Interventional

Octreotide Compared With Loperamide Hydrochloride for Chemotherapy-Related Diarrhea in Patients With Colorectal Cancer

ClinicalTrials.gov ID: NCT00003057

Public ClinicalTrials.gov record NCT00003057. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 3, 2026, 11:12 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Randomized Trial of High-Dose Versus Conventional Dose Octreotide Acetate Versus Loperamide in the Treatment of Chemotherpay-Related Diarrhea in Patients With Colorectal Cancer

Study identification

NCT ID
NCT00003057
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Eastern Cooperative Oncology Group
Network
Enrollment
500 participants

Conditions and interventions

Interventions

  • loperamide hydrochloride Drug
  • octreotide acetate Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 120 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 25, 1997
Primary completion
Apr 30, 2000
Completion
Not listed
Last update posted
Jun 17, 2023

Started 1997

United States locations

U.S. sites
33
U.S. states
20
U.S. cities
27
Facility City State ZIP Site status
University of California San Diego Cancer Center La Jolla California 92093-0658
UCSF Cancer Center and Cancer Research Institute San Francisco California 94115-0128
CCOP - Christiana Care Health Services Wilmington Delaware 19899
Walter Reed Army Medical Center Washington D.C. District of Columbia 20307-5000
CCOP - Mount Sinai Medical Center Miami Beach Florida 33140
University of Illinois at Chicago Health Sciences Center Chicago Illinois 60612
University of Chicago Cancer Research Center Chicago Illinois 60637
University of Iowa Hospitals and Clinics Iowa City Iowa 52242
Marlene & Stewart Greenebaum Cancer Center, University of Maryland Baltimore Maryland 21201
Dana-Farber Cancer Institute Boston Massachusetts 02115
University of Massachusetts Memorial Medical Center Worcester Massachusetts 01655
University of Minnesota Cancer Center Minneapolis Minnesota 55455
Ellis Fischel Cancer Center - Columbia Columbia Missouri 65203
Barnes-Jewish Hospital St Louis Missouri 63110
University of Nebraska Medical Center Omaha Nebraska 68198-3330
CCOP - Southern Nevada Cancer Research Foundation Las Vegas Nevada 89106
Norris Cotton Cancer Center Lebanon New Hampshire 03756
CCOP - North Shore University Hospital Manhasset New York 11030
North Shore University Hospital Manhasset New York 11030
Memorial Sloan-Kettering Cancer Center New York New York 10021
New York Presbyterian Hospital - Cornell Campus New York New York 10021
Mount Sinai Medical Center, NY New York New York 10029
CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C. Syracuse New York 13210
State University of New York - Upstate Medical University Syracuse New York 13210
Lineberger Comprehensive Cancer Center, UNC Chapel Hill North Carolina 27599-7295
Duke Comprehensive Cancer Center Durham North Carolina 27710
CCOP - Southeast Cancer Control Consortium Winston-Salem North Carolina 27104-4241
Comprehensive Cancer Center of Wake Forest University Baptist Medical Center Winston-Salem North Carolina 27157-1082
Rhode Island Hospital Providence Rhode Island 02903
Medical University of South Carolina Charleston South Carolina 29425-0721
University of Tennessee, Memphis Cancer Center Memphis Tennessee 38163
Vermont Cancer Center Burlington Vermont 05401-3498
MBCCOP - Massey Cancer Center Richmond Virginia 23298-0037

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00003057, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 17, 2023 · Synced May 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00003057 live on ClinicalTrials.gov.

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