Radiation Therapy With or Without Cisplatin or Fluorouracil in Treating Patients With Cancer of the Cervix
Public ClinicalTrials.gov record NCT00003078. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Comparison of Radiation vs Radiation Plus Weekly Cisplatin vs Radiation Plus PVI (Protracted Venous Infusion) 5-FU in Patients With Stage II-B, III-B, and IV-A Carcinoma of the Cervix With Negative Paraaortic Nodes
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining radiation therapy and chemotherapy may kill more tumor cells. It is not known whether receiving radiation therapy plus cisplatin is more effective than receiving radiation therapy plus fluorouracil in treating patients with cancer of the cervix. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy plus cisplatin or fluorouracil in treating patients with primary stage IIB, stage IIIB, or stage IVA cancer of the cervix.
Study identification
- NCT ID
- NCT00003078
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 870 participants
Conditions and interventions
Conditions
Interventions
- cisplatin Drug
- fluorouracil Drug
- brachytherapy Radiation
- radiation therapy Radiation
Drug · Radiation
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 1997 (Type not available)
- Primary completion
- Nov 2005 (Actual)
- Completion
- Not listed
- Last update posted
- Jul 9, 2013
Started 1997
United States locations
- U.S. sites
- 65
- U.S. states
- 32
- U.S. cities
- 56
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Comprehensive Cancer Center | Birmingham | Alabama | 35294 | — |
| CCOP - Greater Phoenix | Phoenix | Arizona | 85006-2726 | — |
| USC/Norris Comprehensive Cancer Center | Los Angeles | California | 90033-0800 | — |
| Jonsson Comprehensive Cancer Center, UCLA | Los Angeles | California | 90095-1781 | — |
| Chao Family Comprehensive Cancer Center | Orange | California | 92868 | — |
| Women's Cancer Center | Palo Alto | California | 94304 | — |
| University of Colorado Cancer Center | Denver | Colorado | 80262 | — |
| Vincent T. Lombardi Cancer Research Center, Georgetown University | Washington D.C. | District of Columbia | 20007 | — |
| Walter Reed Army Medical Center | Washington D.C. | District of Columbia | 20307-5000 | — |
| Fred J. Woods Radiation Therapy Center/St. Joseph's Cancer Institute | Tampa | Florida | 33607 | — |
| H. Lee Moffitt Cancer Center and Research Institute | Tampa | Florida | 33612 | — |
| Emory University Hospital - Atlanta | Atlanta | Georgia | 30322 | — |
| MBCCOP - Hawaii | Honolulu | Hawaii | 96813 | — |
| Rush-Presbyterian-St. Luke's Medical Center | Chicago | Illinois | 60612 | — |
| University of Chicago Cancer Research Center | Chicago | Illinois | 60637 | — |
| CCOP - Central Illinois | Decatur | Illinois | 62526 | — |
| CCOP - Evanston | Evanston | Illinois | 60201 | — |
| Indiana University Cancer Center | Indianapolis | Indiana | 46202-5265 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| Albert B. Chandler Medical Center, University of Kentucky | Lexington | Kentucky | 40536-0084 | — |
| Johns Hopkins Oncology Center | Baltimore | Maryland | 21287 | — |
| Medicine Branch | Bethesda | Maryland | 20892 | — |
| Radiation Oncology Branch | Bethesda | Maryland | 20892 | — |
| University of Massachusetts Memorial Medical Center | Worcester | Massachusetts | 01655 | — |
| CCOP - Ann Arbor Regional | Ann Arbor | Michigan | 48106 | — |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216-4505 | — |
| CCOP - Kansas City | Kansas City | Missouri | 64131 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| CCOP - Montana Cancer Consortium | Billings | Montana | 59101 | — |
| CCOP - Missouri Valley Cancer Consortium | Omaha | Nebraska | 68131 | — |
| CCOP - Southern Nevada Cancer Research Foundation | Las Vegas | Nevada | 89106 | — |
| Cooper Hospital/University Medical Center | Camden | New Jersey | 08103 | — |
| Cancer Center of Albany Medical Center | Albany | New York | 12208 | — |
| State University of New York Health Science Center at Brooklyn | Brooklyn | New York | 11203 | — |
| North Shore University Hospital | Manhasset | New York | 11030 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10021 | — |
| University of Rochester Cancer Center | Rochester | New York | 14642 | — |
| State University of New York Health Sciences Center - Stony Brook | Stony Brook | New York | 11790-9832 | — |
| Lineberger Comprehensive Cancer Center, UNC | Chapel Hill | North Carolina | 27599-7295 | — |
| Duke Comprehensive Cancer Center | Durham | North Carolina | 27710 | — |
| Comprehensive Cancer Center of Wake Forest University Baptist Medical Center | Winston-Salem | North Carolina | 27157-1082 | — |
| Barrett Cancer Center, The University Hospital | Cincinnati | Ohio | 45219 | — |
| Ireland Cancer Center | Cleveland | Ohio | 44106-5065 | — |
| Cleveland Clinic Cancer Center | Cleveland | Ohio | 44195 | — |
| Arthur G. James Cancer Hospital - Ohio State University | Columbus | Ohio | 43210 | — |
| University of Oklahoma College of Medicine | Oklahoma City | Oklahoma | 73190 | — |
| CCOP - Sooner State | Tulsa | Oklahoma | 74136 | — |
| CCOP - Columbia River Program | Portland | Oregon | 97213 | — |
| Abington Memorial Hospital | Abington | Pennsylvania | 19001 | — |
| Delaware County Memorial Hospital | Drexel Hill | Pennsylvania | 19026 | — |
| Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| University of Pennsylvania Cancer Center | Philadelphia | Pennsylvania | 19104 | — |
| Kimmel Cancer Center of Thomas Jefferson University - Philadelphia | Philadelphia | Pennsylvania | 19107 | — |
| Pennsylvania Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425-0721 | — |
| CCOP - Upstate Carolina | Spartanburg | South Carolina | 29303 | — |
| CCOP - Baptist Cancer Institute | Memphis | Tennessee | 38117 | — |
| Brookview Research, Inc. | Nashville | Tennessee | 37203 | — |
| Simmons Cancer Center - Dallas | Dallas | Texas | 75235-9154 | — |
| University of Texas - MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Cancer Center, University of Virginia HSC | Charlottesville | Virginia | 22908 | — |
| University of Washington Medical Center | Seattle | Washington | 98195-6043 | — |
| Tacoma General Hospital | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00003078, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 9, 2013 · Synced Oct 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00003078 live on ClinicalTrials.gov.