ClinicalTrials.gov record
Amifostine in Treating Patients With Stage II or Stage III Non-small Cell Lung Cancer
ClinicalTrials.gov ID: NCT00003313
Public ClinicalTrials.gov record NCT00003313. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 19, 2026, 7:04 PM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Randomized Study of Amifostine Mucosal Protection for Patients With Favorable Performance Inoperable Stage II-III A/B Non-Small Cell Lung Cancer (NSCLC) Receiving Sequential Induction and Concurrent Hyperfractionated Radiotherapy With Paclitaxel and Carboplatin
Study identification
- NCT ID
- NCT00003313
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Radiation Therapy Oncology Group
- Network
- Enrollment
- 243 participants
Conditions and interventions
Interventions
- amifostine trihydrate Drug
- carboplatin Drug
- filgrastim Biological
- paclitaxel Drug
- radiation therapy Radiation
Drug · Biological · Radiation
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 31, 1998
- Primary completion
- Jun 30, 2002
- Completion
- May 31, 2010
- Last update posted
- Nov 20, 2014
1998 – 2010
United States locations
- U.S. sites
- 244
- U.S. states
- 47
- U.S. cities
- 194
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham Comprehensive Cancer Center | Birmingham | Alabama | 35294-3300 | — |
| Huntsville Hospital System | Huntsville | Alabama | 35801-4470 | — |
| Comprehensive Cancer Institute of Huntsville | Huntsville | Alabama | 35801 | — |
| MBCCOP - Gulf Coast | Mobile | Alabama | 36688 | — |
| Alabama Oncology, LLC | Montgomery | Alabama | 36106-2801 | — |
| Radiation Oncology Associates of West Alabama | Tuscallosa | Alabama | 35401 | — |
| Providence Alaska Medical Center | Anchorage | Alaska | 99508 | — |
| Foundation for Cancer Research and Education | Phoenix | Arizona | 85013 | — |
| Arizona Cancer Center | Tucson | Arizona | 85724 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Mount Diablo Medical Center | Concord | California | 94524-4110 | — |
| Cancer Center and Beckman Research Institute, City of Hope | Duarte | California | 91010-3000 | — |
| California Cancer Center | Fresno | California | 93720 | — |
| Saint Agnes Cancer Center | Fresno | California | 93720 | — |
| Glendale Memorial Hospital and Health Center | Glendale | California | 91204 | — |
| Sutter Health West Cancer Research Group | Greenbrae | California | 94904 | — |
| University of California San Diego Cancer Center | La Jolla | California | 92093-0658 | — |
| Loma Linda University Medical Center | Loma Linda | California | 92354 | — |
| Veterans Affairs Medical Center - Long Beach | Long Beach | California | 90822 | — |
| USC/Norris Comprehensive Cancer Center and Hospital | Los Angeles | California | 90033-0804 | — |
| Jonsson Comprehensive Cancer Center, UCLA | Los Angeles | California | 90095-1781 | — |
| CCOP - Bay Area Tumor Institute | Oakland | California | 94609-3305 | — |
| Huntington Cancer Center | Pasadena | California | 91105 | — |
| Cancer Care Center | Pomona | California | 91767 | — |
| Radiation Oncology Center - Sacramento | Sacramento | California | 95816 | — |
| Radiation Medical Group, Inc. | San Diego | California | 92101-1492 | — |
| UCSF Cancer Center and Cancer Research Institute | San Francisco | California | 94143-0128 | — |
| O'Connor Hospital | San Jose | California | 95128 | — |
| CCOP - Santa Rosa Memorial Hospital | Santa Rosa | California | 95403 | — |
| David Grant Medical Center | Travis Air Force Base | California | 94535 | — |
| Memorial Hospital Cancer Center | Colorado Springs | Colorado | 80909 | — |
| University of Colorado Cancer Center | Denver | Colorado | 80010 | — |
| Saint Mary's Hospital and Medical Center | Grand Junction | Colorado | 81502 | — |
| CCOP - Christiana Care Health Services | Wilmington | Delaware | 19899 | — |
| Walter Reed Army Medical Center | Washington D.C. | District of Columbia | 20307-5000 | — |
| Lykes Center for Radiation Therapy | Clearwater | Florida | 33757-0210 | — |
| Halifax Medical Center | Daytona Beach | Florida | 32114 | — |
| Radiation Therapy Associates - Fort Myers | Fort Myers | Florida | 33901 | — |
| University of Florida Health Science Center | Gainesville | Florida | 32610-0296 | — |
| Health First Holmes Regional Medical Center | Melbourne | Florida | 32901 | — |
| Veterans Affairs Medical Center - Miami | Miami | Florida | 33125 | — |
| Sylvester Cancer Center, University of Miami | Miami | Florida | 33136 | — |
| Baptist Hospital of Miami | Miami | Florida | 33176-2197 | — |
| CCOP - Mount Sinai Medical Center | Miami Beach | Florida | 33140 | — |
| Florida Radiation Oncology Group | Orange Park | Florida | 32073 | — |
| MD Anderson Cancer Center Orlando | Orlando | Florida | 32806 | — |
| Bay Medical Center | Panama City | Florida | 32401 | — |
| Gulf Coast Cancer Treatment Center | Panama City | Florida | 32405-4587 | — |
| Sarasota Radiation and Medical Oncology Center | Sarasota | Florida | 34233 | — |
| Tallahassee Memorial Healthcare | Tallahassee | Florida | 32308 | — |
| H. Lee Moffitt Cancer Center and Research Institute | Tampa | Florida | 33612-9497 | — |
| Emory University Hospital - Atlanta | Atlanta | Georgia | 30322 | — |
| CCOP - Atlanta Regional | Atlanta | Georgia | 30342-1701 | — |
| Medical Center/John B. Amos Community Cancer Center | Columbus | Georgia | 31902 | — |
| Regional Radiation Oncology Center at Rome | Rome | Georgia | 30165 | — |
| MBCCOP - Hawaii | Honolulu | Hawaii | 96813 | — |
| Northwest Community Hospital | Arlington Heights | Illinois | 60005 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611 | — |
| University of Chicago Cancer Research Center | Chicago | Illinois | 60637-1470 | — |
| CCOP - Central Illinois | Decatur | Illinois | 62526 | — |
| Provena St. Joseph Hospital- Regional Cancer Care Center | Elgin | Illinois | 60123 | — |
| Ingalls Memorial Hospital | Harvey | Illinois | 60426 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| Lutheran General Cancer Care Center | Park Ridge | Illinois | 60068 | — |
| Methodist Medical Center of Illinois | Peoria | Illinois | 61636 | — |
| St. John's Medical Center | Anderson | Indiana | 46016 | — |
| Bloomington Hospital | Bloomington | Indiana | 47402 | — |
| Veterans Affairs Medical Center - Indianapolis (Roudebush) | Indianapolis | Indiana | 46202 | — |
| Clarion Health Partners Inc. | Indianapolis | Indiana | 46206-1367 | — |
| Community Hospitals of Indianapolis - Regional Cancer Center | Indianapolis | Indiana | 46219 | — |
| Ball Memorial Hospital | Muncie | Indiana | 47303-3499 | — |
| CCOP - Northern Indiana CR Consortium | South Bend | Indiana | 46601 | — |
| Wendt Regional Cancer Center of Finley Hospital | Dubuque | Iowa | 52001 | — |
| Holden Comprehensive Cancer Center at The University of Iowa | Iowa City | Iowa | 52242-1009 | — |
| Central Baptist Hospital | Lexington | Kentucky | 40503 | — |
| Veterans Affairs Medical Center - Lexington | Lexington | Kentucky | 40511-1093 | — |
| Albert B. Chandler Medical Center, University of Kentucky | Lexington | Kentucky | 40536-0084 | — |
| James Graham Brown Cancer Center | Louisville | Kentucky | 40202 | — |
| Louisville Radiation Oncology | Louisville | Kentucky | 40215 | — |
| Merle M. Mahr Cancer Center | Madisonville | Kentucky | 42431 | — |
| Mary Bird Perkins Cancer Center | Baton Rouge | Louisiana | 70809 | — |
| Romagosa Radiation Oncology Center | Lafayette | Louisiana | 70501 | — |
| MBCCOP - LSU Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Tulane University School of Medicine | New Orleans | Louisiana | 70112 | — |
| CCOP - Ochsner | New Orleans | Louisiana | 70121 | — |
| Maine Medical Center | Portland | Maine | 04102 | — |
| Anne Arundel Oncology Center | Annapolis | Maryland | 21401 | — |
| Greater Baltimore Medical Center and Cancer Center | Baltimore | Maryland | 21204 | — |
| Harbor Hospital Center | Baltimore | Maryland | 21225 | — |
| Sinai Hospital of Baltimore | Baltimore | Maryland | 21225 | — |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Baltimore | Maryland | 21231-2410 | — |
| Radiation Oncology Affiliates of Maryland, P.A. | Baltimore | Maryland | 21237 | — |
| Peninsula Regional Medical Center | Salisbury | Maryland | 21801 | — |
| Cape Cod Hospital | Hyannis | Massachusetts | 02601 | — |
| Veterans Affairs Medical Center - Boston (Jamaica Plain) | Jamaica Plain | Massachusetts | 02130 | — |
| CCOP - Ann Arbor Regional | Ann Arbor | Michigan | 48106 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109-0752 | — |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201-1379 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| McLaren Regional Cancer Center | Flint | Michigan | 48432 | — |
| Hurley Medical Center | Flint | Michigan | 48503 | — |
| CCOP - Kalamazoo | Kalamazoo | Michigan | 49007-3731 | — |
| Marquette General Hospital | Marquette | Michigan | 49855 | — |
| MidMichigan Medical Center - Midland | Midland | Michigan | 48670 | — |
| William Beaumont Hospital | Royal Oak | Michigan | 48073 | — |
| St. Mary's Medical Center | Saginaw | Michigan | 48601 | — |
| William Beaumont Hospital - Troy | Troy | Michigan | 48098 | — |
| Mayo Clinic Cancer Center | Rochester | Minnesota | 55905 | — |
| CCOP - Metro-Minnesota | Saint Louis Park | Minnesota | 55416 | — |
| North Mississippi Medical Center/Cancer Center | Tupelo | Mississippi | 38801 | — |
| Ellis Fischel Cancer Center - Columbia | Columbia | Missouri | 65203 | — |
| CCOP - Kansas City | Kansas City | Missouri | 64131 | — |
| Cancer Research for the Ozarks | Springfield | Missouri | 65807 | — |
| CCOP - Cancer Research for the Ozarks | Springfield | Missouri | 65807 | — |
| St. Louis University Health Sciences Center | St Louis | Missouri | 63110-0250 | — |
| Mallinckrodt Institute of Radiology | St Louis | Missouri | 63110 | — |
| CCOP - Montana Cancer Consortium | Billings | Montana | 59101 | — |
| Nebraska Health System | Omaha | Nebraska | 68105-1018 | — |
| Methodist Cancer Center - Omaha | Omaha | Nebraska | 68114 | — |
| CCOP - Southern Nevada Cancer Research Foundation | Las Vegas | Nevada | 89106 | — |
| Norris Cotton Cancer Center | Lebanon | New Hampshire | 03756-0002 | — |
| Elliot Regional Cancer Center | Manchester | New Hampshire | 03103 | — |
| Cooper Cancer Institute | Camden | New Jersey | 08103 | — |
| Veterans Affairs Medical Center - East Orange | East Orange | New Jersey | 07018-1095 | — |
| John F. Kennedy Medical Center | Edison | New Jersey | 08818 | — |
| Trinitas Hospital - Jersey Street Campus | Elizabeth | New Jersey | 07201 | — |
| Monmouth Medical Center | Long Branch | New Jersey | 07740-6395 | — |
| South Jersey Regional Cancer Center | Millville | New Jersey | 08332 | — |
| Fox Chase Cancer Center at Virtua Memorial Hospital Burlington County | Mount Holly | New Jersey | 08060 | — |
| Cancer Institute of New Jersey | New Brunswick | New Jersey | 08901 | — |
| Newark Beth Israel Medical Center | Newark | New Jersey | 07112 | — |
| Atlantic City Medical Center | Pomona | New Jersey | 08240 | — |
| Valley Hospital | Ridgewood | New Jersey | 07450 | — |
| Somerset Medical Center | Somerville | New Jersey | 08876 | — |
| Community Medical Center | Toms River | New Jersey | 08755 | — |
| St. Francis Medical Center | Trenton | New Jersey | 08629 | — |
| Associated Radiologists, P.A. | Warren Township | New Jersey | 07059 | — |
| Saint Joseph Medical Center | Albuquerque | New Mexico | 87102 | — |
| Cancer Center of Albany Medical Center | Albany | New York | 12208 | — |
| State University of New York Health Science Center at Brooklyn | Brooklyn | New York | 11203 | — |
| New York Methodist Hospital | Brooklyn | New York | 11215-3609 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263-0001 | — |
| Finger Lakes Radiation Oncology, P.C. | Clifton Springs | New York | 14432 | — |
| CCOP - North Shore University Hospital | Manhasset | New York | 11030 | — |
| Beth Israel Medical Center | New York | New York | 10003 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10021 | — |
| Herbert Irving Comprehensive Cancer Center | New York | New York | 10032 | — |
| Champlain Valley Physicians Hospital Medical Center | Plattsburgh | New York | 12901 | — |
| Vassar Brothers Hospital | Poughkeepsie | New York | 12601 | — |
| University of Rochester Cancer Center | Rochester | New York | 14642 | — |
| CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C. | Syracuse | New York | 13217 | — |
| Albert Einstein Comprehensive Cancer Center | The Bronx | New York | 10461 | — |
| New York Medical College | Valhalla | New York | 10595 | — |
| Riverhill Radiation Oncology | Yonkers | New York | 10701 | — |
| Lineberger Comprehensive Cancer Center, UNC | Chapel Hill | North Carolina | 27599-7295 | — |
| Northeast Medical Center | Concord | North Carolina | 28025 | — |
| East Carolina University School of Medicine | Greenville | North Carolina | 27858-4354 | — |
| Catawba Memorial Hospital | Hickory | North Carolina | 28601 | — |
| CCOP - Southeast Cancer Control Consortium | Winston-Salem | North Carolina | 27104-4241 | — |
| Comprehensive Cancer Center at Wake Forest University | Winston-Salem | North Carolina | 27157-1082 | — |
| Meritcare Roger Maris Cancer Center | Fargo | North Dakota | 58122 | — |
| Trinity Cancer Care Center | Minot | North Dakota | 58701 | — |
| Akron General Medical Center | Akron | Ohio | 44302 | — |
| Akron City Hospital | Akron | Ohio | 44309 | — |
| Barrett Cancer Center, The University Hospital | Cincinnati | Ohio | 45219 | — |
| Christ Hospital | Cincinnati | Ohio | 45219 | — |
| Ireland Cancer Center | Cleveland | Ohio | 44106-5065 | — |
| University Hospitals of Cleveland | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | 44195 | — |
| CCOP - Columbus | Columbus | Ohio | 43206 | — |
| Arthur G. James Cancer Hospital - Ohio State University | Columbus | Ohio | 43210-1240 | — |
| CCOP - Dayton | Kettering | Ohio | 45429 | — |
| CCOP - Toledo Community Hospital Oncology Program | Toledo | Ohio | 43623-3456 | — |
| St. Anthony Hospital | Oklahoma City | Oklahoma | 73101 | — |
| Oklahoma University Medical Center | Oklahoma City | Oklahoma | 73104 | — |
| St. John Health System | Tulsa | Oklahoma | 74104 | — |
| CCOP - Columbia River Program | Portland | Oregon | 97213 | — |
| Lehigh Valley Hospital | Allentown | Pennsylvania | 18103 | — |
| St. Luke's Hospital Regional Cancer Center | Bethlehem | Pennsylvania | 18015 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822-2001 | — |
| Fitzgerald Mercy Hospital | Darby | Pennsylvania | 19023 | — |
| Delaware County Memorial Hospital | Drexel Hill | Pennsylvania | 19026 | — |
| Pocono Cancer Center | East Stroudsburg | Pennsylvania | 18301 | — |
| Penn State Geisinger Cancer Center | Hershey | Pennsylvania | 17033 | — |
| Hahnemann University Hospital | Philadelphia | Pennsylvania | 19102-1192 | — |
| University of Pennsylvania Cancer Center | Philadelphia | Pennsylvania | 19104-4283 | — |
| Veterans Affairs Medical Center - Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| Kimmel Cancer Center of Thomas Jefferson University - Philadelphia | Philadelphia | Pennsylvania | 19107-5541 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| Albert Einstein Cancer Center | Philadelphia | Pennsylvania | 19141 | — |
| University of Pittsburgh Cancer Institute | Pittsburgh | Pennsylvania | 15213-3489 | — |
| Mercy Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15219 | — |
| Western Pennsylvania Hospital | Pittsburgh | Pennsylvania | 15224 | — |
| Reading Hospital and Medical Center | Reading | Pennsylvania | 19612-6052 | — |
| Mercy Hospital Cancer Center - Scranton | Scranton | Pennsylvania | 18501 | — |
| Grand View Hospital | Sellersville | Pennsylvania | 18960 | — |
| Wilkes Barre General Hospital | Wilkes-Barre | Pennsylvania | 18764 | — |
| CCOP - MainLine Health | Wynnewood | Pennsylvania | 19096 | — |
| York Hospital | York | Pennsylvania | 17315 | — |
| Roger Williams Medical Center/BUSM | Providence | Rhode Island | 02908-4735 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425-0721 | — |
| CCOP - Greenville | Greenville | South Carolina | 29615 | — |
| CCOP - Upstate Carolina | Spartanburg | South Carolina | 29303 | — |
| Rapid City Regional Hospital | Rapid City | South Dakota | 57709 | — |
| Jackson-Madison County General Hospital | Jackson | Tennessee | 38301 | — |
| University of Tennessee, Memphis Cancer Center | Memphis | Tennessee | 38103 | — |
| Vanderbilt-Ingram Cancer Center | Nashville | Tennessee | 37232-6838 | — |
| Harrington Cancer Center | Amarillo | Texas | 79106 | — |
| Julie and Ben Rogers Cancer Institute | Beaumont | Texas | 77701 | — |
| University of Texas Medical Branch | Galveston | Texas | 77555-0209 | — |
| University of Texas - MD Anderson Cancer Center | Houston | Texas | 77030-4009 | — |
| Wilford Hall - 59th Medical Wing | Lackland Air Force Base | Texas | 78236-5300 | — |
| Joe Arrington Cancer Research and Treatment Center | Lubbock | Texas | 79410-1894 | — |
| Bayshore Medical Center | Pasadena | Texas | 77504 | — |
| East Texas Medical Center - Cancer Institute | Tyler | Texas | 75701 | — |
| University of Utah Health Sciences Center | Salt Lake City | Utah | 84132 | — |
| LDS Hospital | Salt Lake City | Utah | 84143 | — |
| Dixie Regional Medical Center | St. George | Utah | 84770 | — |
| CCOP - Southwestern Vermont Regional Cancer Center | Bennington | Vermont | 05201 | — |
| Vermont Cancer Center | Burlington | Vermont | 05401-3498 | — |
| Green Mountain Oncology Group | Rutland | Vermont | 05701 | — |
| Martha Jefferson Hospital | Charlottesville | Virginia | 22901 | — |
| Cancer Center at the University of Virginia | Charlottesville | Virginia | 22908 | — |
| RMH Regional Canter Center | Harrisonburg | Virginia | 22801 | — |
| Naval Medical Center, Portsmouth | Portsmouth | Virginia | 23708-2197 | — |
| Bon-Secours - St. Mary's Hospital | Richmond | Virginia | 23226 | — |
| Massey Cancer Center | Richmond | Virginia | 23298-0037 | — |
| Virginia Mason Medical Center | Seattle | Washington | 98111 | — |
| Deaconess Medical Center | Spokane | Washington | 99210-0248 | — |
| Yakima Valley Memorial Hospital | Yakima | Washington | 98902 | — |
| Schiffler Cancer Center | Wheeling | West Virginia | 26003 | — |
| St. Vincent Hospital | Green Bay | Wisconsin | 54307-3508 | — |
| Gundersen Lutheran Medical Foundation | La Crosse | Wisconsin | 54601 | — |
| Southern Wisconsin Radiotherapy Center | Madison | Wisconsin | 53713 | — |
| University of Wisconsin Comprehensive Cancer Center | Madison | Wisconsin | 53792-6164 | — |
| Marshfield Clinic | Marshfield | Wisconsin | 54449 | — |
| Community Memorial Hospital | Menomonee Falls | Wisconsin | 53051 | — |
| St. Joseph's Hospital | Milwaukee | Wisconsin | 53210 | — |
| Columbia Hospital | Milwaukee | Wisconsin | 53211 | — |
| St. Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
| Veterans Affairs Medical Center - Milwaukee (Zablocki) | Milwaukee | Wisconsin | 53295 | — |
| Southeastern Wisconsin Regional Cancer Center | Racine | Wisconsin | 53405 | — |
| Waukesha Memorial Hospital | Waukesha | Wisconsin | 53188 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00003313, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 20, 2014 · Synced May 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00003313 live on ClinicalTrials.gov.