Radiation Therapy Plus Gadolinium Texaphyrin in Treating Patients With Brain Metastases
Public ClinicalTrials.gov record NCT00003563. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase III Randomized Trial of Gadolinium Texaphyrin (PCI-0120) Injection as a Radiation Sensitizer in Patients Receiving Whole Brain Radiation Therapy for the Treatment of Brain Metastases
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Gadolinium texaphyrin may increase the effectiveness of radiation therapy by making tumor cells more sensitive to radiation. It is not yet known whether giving gadolinium texaphyrin with radiation therapy is more effective than radiation therapy alone in treating brain metastases. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy with or without gadolinium texaphyrin in treating patients who have brain metastases.
Study identification
- NCT ID
- NCT00003563
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 430 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 1998 (Type not available)
- Primary completion
- Sep 2001 (Actual)
- Completion
- Jun 2005 (Actual)
- Last update posted
- Oct 31, 2013
1998 – 2005
United States locations
- U.S. sites
- 31
- U.S. states
- 18
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Marin Oncology Associates, Inc. | Greenbrae | California | 94904 | — |
| Kaiser Permanente Medical Group | Los Angeles | California | 90027 | — |
| Jonsson Comprehensive Cancer Center, UCLA | Los Angeles | California | 90095-1781 | — |
| Beckman Research Institute, City of Hope | Los Angeles | California | 91010 | — |
| Radiation Oncology Center - Sacramento | Sacramento | California | 95816 | — |
| University of Colorado Cancer Center | Denver | Colorado | 80262 | — |
| Charlotte County Radiation Therapy Regional Center | Port Charlotte | Florida | 33952 | — |
| Emory Clinic | Atlanta | Georgia | 30365 | — |
| Indiana University Cancer Center | Indianapolis | Indiana | 46202-5265 | — |
| Hematology and Oncology Services - Metairie | Metairie | Louisiana | 70006 | — |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | — |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Harper Hospital and Wayne State University | Detroit | Michigan | 48201 | — |
| Veterans Affairs Medical Center - Minneapolis | Minneapolis | Minnesota | 55417 | — |
| North Memorial Research Center | Minneapolis | Minnesota | 55442-2900 | — |
| Cancer Institute of New Jersey | New Brunswick | New Jersey | 08901 | — |
| New Mexico Oncology-Hematology | Albuquerque | New Mexico | 87102 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10021 | — |
| Barrett Cancer Center, The University Hospital | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | 44195 | — |
| Abington Hematology Oncology Associates | Meadowbrook | Pennsylvania | 18974 | — |
| Kimmel Cancer Center of Thomas Jefferson University - Philadelphia | Philadelphia | Pennsylvania | 19107 | — |
| Presbyterian-University Hospital | Pittsburgh | Pennsylvania | 15213 | — |
| Mercy Hospital Cancer Center - Scranton | Scranton | Pennsylvania | 18501 | — |
| Thompson Cancer Survival Center | Knoxville | Tennessee | 37916 | — |
| Vanderbilt Cancer Center | Nashville | Tennessee | 37232-6838 | — |
| University of Texas - MD Anderson Cancer Center | Houston | Texas | 77030-4009 | — |
| Scott and White Memorial Hospital | Temple | Texas | 76508 | — |
| Virginia Mason Medical Center | Seattle | Washington | 98111 | — |
| University of Wisconsin Comprehensive Cancer Center | Madison | Wisconsin | 53792 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00003563, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 31, 2013 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00003563 live on ClinicalTrials.gov.