Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Brain Stem Glioma
Public ClinicalTrials.gov record NCT00003625. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Vincristine, Etoposide and Cyclosporine A in Concert With Standard Dose Radiation Therapy in Diffuse Intrinsic Brain Stem Glioma - A Phase I Study of Dose Escalation of Vincristine
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining more than one chemotherapy drug with radiation therapy may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of combination chemotherapy plus radiation therapy in treating patients with newly diagnosed brain stem glioma.
Study identification
- NCT ID
- NCT00003625
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 7 participants
Conditions and interventions
Conditions
Interventions
- cyclosporine Drug
- etoposide Drug
- vincristine sulfate Drug
- radiation therapy Radiation
Drug · Radiation
Eligibility (public fields only)
- Age range
- 3 Years to 21 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 1998 (Type not available)
- Primary completion
- Feb 2001 (Actual)
- Completion
- Apr 2006 (Actual)
- Last update posted
- Jul 28, 2014
1998 – 2006
United States locations
- U.S. sites
- 65
- U.S. states
- 30
- U.S. cities
- 57
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Comprehensive Cancer Center | Birmingham | Alabama | 35294 | — |
| Arizona Cancer Center | Tucson | Arizona | 85724 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| University of California San Diego Cancer Center | La Jolla | California | 92093-0658 | — |
| Lucile Packard Children's Hospital at Stanford | Palo Alto | California | 94304 | — |
| Sutter Cancer Center | Sacramento | California | 95816 | — |
| Kaiser Permanente-Southern California Permanente Medical Group | San Diego | California | 92120 | — |
| Naval Medical Center - San Diego | San Diego | California | 92134-3202 | — |
| Kaiser Permanente Medical Center - Santa Clara | Santa Clara | California | 95051-5386 | — |
| Nemours Children's Clinic | Jacksonville | Florida | 32207 | — |
| Sylvester Cancer Center, University of Miami | Miami | Florida | 33136 | — |
| Baptist Hospital of Miami | Miami | Florida | 33176-2197 | — |
| Walt Disney Memorial Cancer Institute | Orlando | Florida | 32803 | — |
| St. Mary's Hospital | West Palm Beach | Florida | 33407 | — |
| Emory University Hospital - Atlanta | Atlanta | Georgia | 30322 | — |
| Tripler Army Medical Center | Honolulu | Hawaii | 96859-5000 | — |
| Rush-Presbyterian-St. Luke's Medical Center | Chicago | Illinois | 60612 | — |
| Children's Memorial Hospital, Chicago | Chicago | Illinois | 60614 | — |
| Christ Hospital | Oak Lawn | Illinois | 60453 | — |
| Saint Jude Midwest Affiliate | Peoria | Illinois | 61602 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160-7357 | — |
| Via Christi Regional Medical Center-Saint Francis Campus | Wichita | Kansas | 67214 | — |
| Tulane University School of Medicine | New Orleans | Louisiana | 70112 | — |
| Eastern Maine Medical Center | Bangor | Maine | 04401 | — |
| Maine Children's Cancer Program | Portland | Maine | 04101 | — |
| Johns Hopkins Oncology Center | Baltimore | Maryland | 21287 | — |
| Floating Hospital for Children | Boston | Massachusetts | 02111 | — |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| Children's Hospital of Michigan | Detroit | Michigan | 48201 | — |
| St. John's Hospital and Medical Center | Detroit | Michigan | 48236 | — |
| Hurley Medical Center | Flint | Michigan | 48503 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216-4505 | — |
| Keesler Medical Center - Keesler AFB | Keesler Air Force Base | Mississippi | 39534-2576 | — |
| University of Missouri-Columbia Hospital and Clinics | Columbia | Missouri | 65212 | — |
| Cardinal Glennon Children's Hospital | St Louis | Missouri | 63104 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Norris Cotton Cancer Center | Lebanon | New Hampshire | 03756 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| University of New Mexico School of Medicine | Albuquerque | New Mexico | 87131 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263-0001 | — |
| State University of New York Health Sciences Center - Stony Brook | Stony Brook | New York | 11790-9832 | — |
| State University of New York - Upstate Medical University | Syracuse | New York | 13210 | — |
| Duke Comprehensive Cancer Center | Durham | North Carolina | 27710 | — |
| Oklahoma Memorial Hospital | Oklahoma City | Oklahoma | 73126-0307 | — |
| Natalie Warren Bryant Cancer Center | Tulsa | Oklahoma | 74136 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425-0721 | — |
| James H. Quillen College of Medicine | Johnson City | Tennessee | 37614-0622 | — |
| Saint Jude Children's Research Hospital | Memphis | Tennessee | 38105-2794 | — |
| Medical City Dallas Hospital | Dallas | Texas | 75230 | — |
| Simmons Cancer Center - Dallas | Dallas | Texas | 75235-9154 | — |
| Cook Children's Medical Center - Fort Worth | Fort Worth | Texas | 76104 | — |
| University of Texas Medical Branch | Galveston | Texas | 77555-1329 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| San Antonio Military Pediatric Cancer and Blood Disorders Center | Lackland Air Force Base | Texas | 78236-5300 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78284 | — |
| Scott and White Clinic | Temple | Texas | 76508 | — |
| Vermont Cancer Center | Burlington | Vermont | 05401-3498 | — |
| Inova Fairfax Hospital | Falls Church | Virginia | 22046 | — |
| Carilion Roanoke Memorial Hospital | Roanoke | Virginia | 24029 | — |
| Madigan Army Medical Center | Tacoma | Washington | 98431-5000 | — |
| West Virginia University Medical School, Charleston Division | Charleston | West Virginia | 25304 | — |
| West Virginia University Hospitals | Morgantown | West Virginia | 26506-9162 | — |
| St. Vincent Hospital | Green Bay | Wisconsin | 54307-3508 | — |
| Midwest Children's Cancer Center | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00003625, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 28, 2014 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00003625 live on ClinicalTrials.gov.