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Completed Phase 1 Interventional

O6-benzylguanine and Carmustine in Treating Children With Refractory CNS Tumors

ClinicalTrials.gov ID: NCT00003765

Public ClinicalTrials.gov record NCT00003765. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 26, 2026, 3:28 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Trial of 06-BG and BCNU in Children With CNS Tumors

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Phase I trial to study the effectiveness of O6-benzylguanine and carmustine in treating children who have refractory CNS tumors. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.

Study identification

NCT ID
NCT00003765
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Enrollment
36 participants

Conditions and interventions

Eligibility (public fields only)

Age range
Up to 21 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 1999 (Type not available)
Primary completion
Mar 2006 (Actual)
Completion
Not listed
Last update posted
Feb 5, 2013

Started 1999

United States locations

U.S. sites
51
U.S. states
26
U.S. cities
43
Facility City State ZIP Site status
University of Arkansas for Medical Sciences Little Rock Arkansas 72205 —
University of California San Diego Cancer Center La Jolla California 92093-0658 —
Children's Hospital Los Angeles Los Angeles California 90027-0700 —
Jonsson Comprehensive Cancer Center, UCLA Los Angeles California 90095-1781 —
City of Hope National Medical Center Los Angeles California 91010 —
Children's Hospital of Orange County Orange California 92868 —
UCSF Cancer Center and Cancer Research Institute San Francisco California 94115-0128 —
Stanford University Medical Center Stanford California 94305-5408 —
Children's National Medical Center Washington D.C. District of Columbia 20010-2970 —
University of Florida Health Science Center Gainesville Florida 32610-0296 —
Emory University Hospital - Atlanta Atlanta Georgia 30322 —
Robert H. Lurie Comprehensive Cancer Center, Northwestern University Chicago Illinois 60611 —
Children's Memorial Hospital, Chicago Chicago Illinois 60614 —
Indiana University Cancer Center Indianapolis Indiana 46202-5265 —
University of Kansas Medical Center Kansas City Kansas 66160-7357 —
Johns Hopkins Oncology Center Baltimore Maryland 21231 —
Boston Floating Hospital Infants and Children Boston Massachusetts 02111 —
Dana-Farber Cancer Institute Boston Massachusetts 02115 —
University of Michigan Comprehensive Cancer Center Ann Arbor Michigan 48109-0752 —
Children's Hospital of Michigan Detroit Michigan 48201 —
University of Minnesota Cancer Center Minneapolis Minnesota 55455 —
Mayo Clinic Cancer Center Rochester Minnesota 55905 —
University of Mississippi Medical Center Jackson Mississippi 39216-4505 —
Children's Mercy Hospital Kansas City Missouri 64108 —
Cardinal Glennon Children's Hospital St Louis Missouri 63104 —
Washington University School of Medicine St Louis Missouri 63110 —
Hackensack University Medical Center Hackensack New Jersey 07601 —
Cancer Institute of New Jersey New Brunswick New Jersey 08901 —
Roswell Park Cancer Institute Buffalo New York 14263-0001 —
NYU School of Medicine's Kaplan Comprehensive Cancer Center New York New York 10016 —
Memorial Sloan-Kettering Cancer Center New York New York 10021 —
Columbia Presbyterian Hospital New York New York 10032 —
State University of New York - Upstate Medical University Syracuse New York 13210 —
Graham Children's Health Center Asheville North Carolina 28801 —
Duke Comprehensive Cancer Center Durham North Carolina 27710 —
Children's Hospital Medical Center - Cincinnati Cincinnati Ohio 45229-3039 —
Children's Hospital of Columbus Columbus Ohio 43205-2696 —
University of Oklahoma Health Sciences Center Oklahoma City Oklahoma 73190 —
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104 —
Children's Hospital of Pittsburgh Pittsburgh Pennsylvania 15213 —
Medical University of South Carolina Charleston South Carolina 29425-0721 —
Vanderbilt Cancer Center Nashville Tennessee 37232-6838 —
Simmons Cancer Center - Dallas Dallas Texas 75235-9154 —
Cook Children's Medical Center - Fort Worth Fort Worth Texas 76104 —
Texas Children's Cancer Center Houston Texas 77030-2399 —
University of Texas - MD Anderson Cancer Center Houston Texas 77030-4009 —
University of Texas Health Science Center at San Antonio San Antonio Texas 78284-7811 —
Primary Children's Medical Center Salt Lake City Utah 84113 —
Children's Hospital and Regional Medical Center - Seattle Seattle Washington 98105 —
University of Wisconsin Comprehensive Cancer Center Madison Wisconsin 53792 —
Midwest Children's Cancer Center Milwaukee Wisconsin 53226 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00003765, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 5, 2013 · Synced Oct 26, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00003765 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →