ClinicalTrials.gov record
Combination Chemotherapy in Treating Women With Stage I, Stage II, or Stage IIIA (cT1-3, N0-1, M0) Breast Cancer and Positive Axillary Lymph Nodes
ClinicalTrials.gov ID: NCT00003782
Public ClinicalTrials.gov record NCT00003782. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Three-Arm Randomized Trial to Compare Adjuvant Adriamycin and Cyclophosphamide Followed by Taxotere (AC-T); Adriamycin and Taxotere (AT); and Adriamycin, Taxotere, and Cyclophosphamide (ATC) in Breast Cancer Patients With Positive Axillary Lymph Nodes
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving combination chemotherapy after surgery may kill any tumor cells remaining following surgery. It is not yet known which regimen of combination chemotherapy is more effective in treating breast cancer with positive axillary lymph nodes. PURPOSE: Randomized phase III trial to compare the effectiveness of different regimens of combination chemotherapy in treating women who have undergone surgery for stage I, stage II, or stage IIIA breast cancer with positive axillary lymph nodes.
Study identification
- NCT ID
- NCT00003782
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 5,351 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 120 Years
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 1999 (Type not available)
- Primary completion
- Dec 2008 (Actual)
- Completion
- Dec 2012 (Actual)
- Last update posted
- Mar 21, 2024
1999 – 2012
United States locations
- U.S. sites
- 146
- U.S. states
- 45
- U.S. cities
- 126
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Comprehensive Cancer Institute | Huntsville | Alabama | 35801 | — |
| Providence Alaska Medical Center | Anchorage | Alaska | 99519-6604 | — |
| CCOP - Western Regional, Arizona | Phoenix | Arizona | 85006-2726 | — |
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010-3000 | — |
| California Cancer Center | Fresno | California | 93720 | — |
| Sutter Health Western Division Cancer Research Group | Greenbrae | California | 94904 | — |
| Scripps Cancer Center at Scripps Clinic | La Jolla | California | 92037 | — |
| Rebecca and John Moores UCSD Cancer Center | La Jolla | California | 92093-0658 | — |
| Loma Linda University Cancer Institute at Loma Linda University Medical Center | Loma Linda | California | 92354 | — |
| Pacific Shores Medical Group | Long Beach | California | 90813 | — |
| CCOP - Bay Area Tumor Institute | Oakland | California | 94609-3305 | — |
| Chao Family Comprehensive Cancer Center at University of California Irvine Cancer Center | Orange | California | 92868 | — |
| Comprehensive Cancer Centers of the Desert | Palm Springs | California | 92262 | — |
| Stanford Cancer Center at Stanford University Medical Center | Palo Alto | California | 94305-5408 | — |
| Sutter Cancer Center | Sacramento | California | 95816 | — |
| Kaiser Permanente Medical Center/Kaiser Foundation Hospital - San Diego | San Diego | California | 92120 | — |
| Catholic Healthcare West - Westbay Region | San Francisco | California | 94107-1728 | — |
| CCOP - Santa Rosa Memorial Hospital | Santa Rosa | California | 95403 | — |
| Kaiser Permanente Medical Center - Vallejo | Vallejo | California | 94589 | — |
| University of Colorado Cancer Center at University of Colorado Health Sciences Center | Denver | Colorado | 80010 | — |
| CCOP - Colorado Cancer Research Program, Incorporated | Denver | Colorado | 80209-5031 | — |
| University of Connecticut Cancer Center at University of Connecticut Health Center | Farmington | Connecticut | 06360-7106 | — |
| Hartford Hospital | Hartford | Connecticut | 06102-5037 | — |
| CCOP - Christiana Care Health Services | Wilmington | Delaware | 19899 | — |
| MBCCOP - Howard University Cancer Center | Washington D.C. | District of Columbia | 20060 | — |
| Morton Plant Hospital | Clearwater | Florida | 33756 | — |
| Halifax Medical Center | Daytona Beach | Florida | 32114 | — |
| Baptist Regional Cancer Institute - Jacksonville | Jacksonville | Florida | 32207 | — |
| University of Miami Sylvester Cancer Center | Miami | Florida | 33136 | — |
| CCOP - Mount Sinai Medical Center | Miami Beach | Florida | 33140 | — |
| MD Anderson Cancer Center Orlando | Orlando | Florida | 32806 | — |
| Sarasota Memorial Hospital | Sarasota | Florida | 34239 | — |
| Winship Cancer Institute of Emory University | Atlanta | Georgia | 30322 | — |
| CCOP - Atlanta Regional | Atlanta | Georgia | 30342-1701 | — |
| Medical College of Georgia Comprehensive Cancer Center | Augusta | Georgia | 30912-4000 | — |
| Dwight David Eisenhower Army Medical Center | Fort Gordon | Georgia | 30905-5650 | — |
| Cancer Research Center of Hawaii | Honolulu | Hawaii | 96813 | — |
| North Idaho Cancer Center | Coeur d'Alene | Idaho | 83814 | — |
| John H. Stroger, Jr. Hospital of Cook County | Chicago | Illinois | 60612-9985 | — |
| Rush-Presbyterian-St. Luke's Medical Center | Chicago | Illinois | 60612 | — |
| Creticos Cancer Center at Advocate Illinois Masonic Medical Center | Chicago | Illinois | 60657 | — |
| CCOP - Central Illinois | Decatur | Illinois | 62526 | — |
| CCOP - Evanston | Evanston | Illinois | 60201 | — |
| CCOP - Illinois Oncology Research Association | Peoria | Illinois | 61602 | — |
| CCOP - Carle Cancer Center | Urbana | Illinois | 61801 | — |
| Methodist Cancer Center at Methodist Hospital | Indianapolis | Indiana | 46206-1367 | — |
| St. Vincent Hospital and Health Care Center | Indianapolis | Indiana | 46260 | — |
| Community Hospital | Munster | Indiana | 46321 | — |
| Genesis Medical Center | Davenport | Iowa | 52804 | — |
| CCOP - Iowa Oncology Research Association | Des Moines | Iowa | 50309-1016 | — |
| Holden Comprehensive Cancer Center at University of Iowa | Iowa City | Iowa | 52242-1009 | — |
| CCOP - Wichita | Wichita | Kansas | 67214-3882 | — |
| Markey Cancer Center at University of Kentucky Chandler Medical Center | Lexington | Kentucky | 40536-0093 | — |
| Norton Healthcare Cancer Center | Louisville | Kentucky | 40202-5070 | — |
| Consultants in Blood Disorders and Cancer | Louisville | Kentucky | 40207 | — |
| Stanley S. Scott Cancer Center at Louisiana State University Medical Center - New Orleans | New Orleans | Louisiana | 70112 | — |
| Tulane University Medical Center | New Orleans | Louisiana | 70112 | — |
| CCOP - Ochsner | New Orleans | Louisiana | 70121 | — |
| Eastern Maine Medical Center | Bangor | Maine | 04401 | — |
| Franklin Square Hospital Center | Baltimore | Maryland | 21237 | — |
| National Naval Medical Center | Bethesda | Maryland | 20889-5000 | — |
| Cancer Research Center at Boston Medical Center | Boston | Massachusetts | 02118 | — |
| Lahey Clinic Medical Center - Burlington | Burlington | Massachusetts | 01805 | — |
| Berkshire Medical Center | Pittsfield | Massachusetts | 01201 | — |
| Baystate Medical Center | Springfield | Massachusetts | 01199 | — |
| CCOP - Michigan Cancer Research Consortium | Ann Arbor | Michigan | 48106 | — |
| Josephine Ford Cancer Center at Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Michigan State University | East Lansing | Michigan | 48824 | — |
| CCOP - Grand Rapids | Grand Rapids | Michigan | 49503 | — |
| CCOP - Kalamazoo | Kalamazoo | Michigan | 49007-3731 | — |
| CCOP - Beaumont | Royal Oak | Michigan | 48073-6769 | — |
| Providence Cancer Institute at Providence Hospital | Southfield | Michigan | 48075-9975 | — |
| CCOP - Duluth | Duluth | Minnesota | 55805 | — |
| Hennepin County Medical Center - Minneapolis | Minneapolis | Minnesota | 55415 | — |
| CCOP - Metro-Minnesota | Saint Louis Park | Minnesota | 55416 | — |
| Ellis Fischel Cancer Center at University of Missouri - Columbia | Columbia | Missouri | 65203 | — |
| CCOP - Kansas City | Kansas City | Missouri | 64131 | — |
| CCOP - Cancer Research for the Ozarks | Springfield | Missouri | 65807 | — |
| St. Louis University Hospital Cancer Center | St Louis | Missouri | 63110-0250 | — |
| CCOP - St. Louis-Cape Girardeau | St Louis | Missouri | 63141 | — |
| CCOP - Montana Cancer Consortium | Billings | Montana | 59101 | — |
| Methodist Hospital Cancer Center at Nebraska Methodist Hospital - Omaha | Omaha | Nebraska | 68114 | — |
| CCOP - Missouri Valley Cancer Consortium | Omaha | Nebraska | 68131 | — |
| CCOP - Southern Nevada Cancer Research Foundation | Las Vegas | Nevada | 89106 | — |
| CCOP - Northern New Jersey | Hackensack | New Jersey | 07601 | — |
| Cancer Institute of New Jersey | New Brunswick | New Jersey | 08903 | — |
| Newark Beth Israel Medical Center | Newark | New Jersey | 07112 | — |
| MBCCOP - University of New Mexico HSC | Albuquerque | New Mexico | 87131 | — |
| New York Oncology Hematology, P.C. - Albany Regional Cancer Center | Albany | New York | 12208 | — |
| Charles R. Wood Foundation Cancer Center at Glens Falls Hospital | Glens Falls | New York | 12801 | — |
| Staten Island University Hospital | Staten Island | New York | 10305 | — |
| CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C. | Syracuse | New York | 13217 | — |
| Lincoln Medical and Mental Health Center | The Bronx | New York | 10451 | — |
| MBCCOP-Our Lady of Mercy Cancer Center | The Bronx | New York | 10466 | — |
| Alamance Cancer Center | Burlington | North Carolina | 27216 | — |
| Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill | Chapel Hill | North Carolina | 27599-7295 | — |
| Leo W. Jenkins Cancer Center of University Health Systems of Eastern Carolina | Greenville | North Carolina | 27858-4354 | — |
| CCOP - Southeast Cancer Control Consortium | Winston-Salem | North Carolina | 27104-4241 | — |
| Comprehensive Cancer Center at Wake Forest University | Winston-Salem | North Carolina | 27157-1082 | — |
| CCOP - Merit Care Hospital | Fargo | North Dakota | 58122 | — |
| Akron City Hospital | Akron | Ohio | 44309 | — |
| Aultman Hospital Cancer Center at Aultman Health Foundation | Canton | Ohio | 44710 | — |
| Jewish Hospital of Cincinnati, Incorporated | Cincinnati | Ohio | 45236 | — |
| Charles M. Barrett Cancer Center at University Hospital | Cincinnati | Ohio | 45267-0502 | — |
| CCOP - Columbus | Columbus | Ohio | 43206 | — |
| Arthur G. James Cancer Hospital - Ohio State University | Columbus | Ohio | 43210-1240 | — |
| CCOP - Dayton | Kettering | Ohio | 45429 | — |
| CCOP - Toledo Community Hospital | Toledo | Ohio | 43623-3456 | — |
| South Pointe Hospital - Cancer Care Center | Warrensville Heights | Ohio | 44122 | — |
| CCOP - Oklahoma | Tulsa | Oklahoma | 74136 | — |
| CCOP - Columbia River Oncology Program | Portland | Oregon | 97213 | — |
| John and Dorothy Morgan Cancer Center at Lehigh Valley Hospital | Allentown | Pennsylvania | 18103 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822-2001 | — |
| Kimmel Cancer Center at Thomas Jefferson University - Philadelphia | Philadelphia | Pennsylvania | 19107-5541 | — |
| Albert Einstein Cancer Center | Philadelphia | Pennsylvania | 19141 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212-4772 | — |
| Hillman Cancer Center at University of Pittsburgh Cancer Institute | Pittsburgh | Pennsylvania | 15213-3489 | — |
| Reading Hospital and Medical Center | Reading | Pennsylvania | 19612-6052 | — |
| Mercy Hospital Cancer Center - Scranton | Scranton | Pennsylvania | 18501 | — |
| CCOP - MainLine Health | Wynnewood | Pennsylvania | 19096 | — |
| Wellspan Health - York Cancer Center | York | Pennsylvania | 17315 | — |
| CCOP - Greenville | Greenville | South Carolina | 29615 | — |
| CCOP - Upstate Carolina | Spartanburg | South Carolina | 29303 | — |
| Thompson Cancer Survival Center | Knoxville | Tennessee | 37916 | — |
| Baptist Cancer Institute - Memphis at Baptist Memorial Hospital - Memphis | Memphis | Tennessee | 38146 | — |
| Medical City Dallas Hospital | Dallas | Texas | 75230 | — |
| Simmons Cancer Center at University of Texas Southwestern Medical Center - Dallas | Dallas | Texas | 75235-9154 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Joe Arrington Cancer Research and Treatment Center | Lubbock | Texas | 79410-1894 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78284-7811 | — |
| CCOP - Scott and White Hospital | Temple | Texas | 76508 | — |
| Utah Valley Regional Medical Center - Provo | Provo | Utah | 84604 | — |
| Green Mountain Oncology Group | Bennington | Vermont | 05201 | — |
| Virginia Oncology Associates - Newport News | Newport News | Virginia | 23606 | — |
| Eastern Virginia Medical School | Norfolk | Virginia | 23507 | — |
| MBCCOP - Massey Cancer Center | Richmond | Virginia | 23298-0037 | — |
| Oncology and Hematology Associates of Southwest Virginia, Inc. | Roanoke | Virginia | 24014 | — |
| CCOP - Virginia Mason Research Center | Seattle | Washington | 98101 | — |
| Puget Sound Oncology Consortium | Seattle | Washington | 98109 | — |
| CCOP - Northwest | Tacoma | Washington | 98405-0986 | — |
| Charleston Area Medical Center | Charleston | West Virginia | 25304-1297 | — |
| Camden-Clark Memorial Hospital | Parkersburg | West Virginia | 26102 | — |
| CCOP - St. Vincent Hospital Cancer Center, Green Bay | Green Bay | Wisconsin | 54301 | — |
| CCOP - Marshfield Clinic Research Foundation | Marshfield | Wisconsin | 54449 | — |
| St. Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
| Medical College of Wisconsin Cancer Center | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00003782, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 21, 2024 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00003782 live on ClinicalTrials.gov.