ClinicalTrials.gov record
Combination Chemotherapy Plus Amifostine in Treating Children With Malignant Germ Cell Tumors
ClinicalTrials.gov ID: NCT00003811
Public ClinicalTrials.gov record NCT00003811. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
High-Dose Cisplatin, Etoposide and Bleomycin (HD-PEB) Combined With Amifostine in Children With High-Risk Malignant Germ Cell Tumors - A POG Pilot Study
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Chemotherapy drugs use different ways to stop tumor cells from dividing so they stop growing or die. Chemoprotective drugs such as amifostine may protect normal cells from the side effects of chemotherapy. PURPOSE: Phase I trial to study the effectiveness of high-dose cisplatin, etoposide, and bleomycin plus amifostine in treating children who have malignant germ cell tumors.
Study identification
- NCT ID
- NCT00003811
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 27 participants
Conditions and interventions
Conditions
Interventions
- bleomycin sulfate Biological
- amifostine trihydrate Drug
- cisplatin Drug
- etoposide Drug
- conventional surgery Procedure
Biological · Drug · Procedure
Eligibility (public fields only)
- Age range
- Up to 14 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2000 (Type not available)
- Primary completion
- Oct 2004 (Actual)
- Completion
- Sep 2007 (Actual)
- Last update posted
- Jul 4, 2013
2000 – 2007
United States locations
- U.S. sites
- 97
- U.S. states
- 34
- U.S. cities
- 77
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham Comprehensive Cancer Center | Birmingham | Alabama | 35294-3300 | — |
| MBCCOP - Gulf Coast | Mobile | Alabama | 36688 | — |
| Arizona Cancer Center | Tucson | Arizona | 85724 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| University of California San Diego Cancer Center | La Jolla | California | 92093-0658 | — |
| Lucile Packard Children's Hospital at Stanford | Palo Alto | California | 94304 | — |
| Sutter Cancer Center | Sacramento | California | 95816 | — |
| University of California Davis Medical Center | Sacramento | California | 95817 | — |
| Kaiser Permanente-Southern California Permanente Medical Group | San Diego | California | 92120 | — |
| Children's Hospital and Health Center | San Diego | California | 92123-4282 | — |
| Naval Medical Center - San Diego | San Diego | California | 92134-3202 | — |
| Kaiser Permanente Medical Center - Santa Clara | Santa Clara | California | 95051-5386 | — |
| Stanford University Medical Center | Stanford | California | 94305-5408 | — |
| Yale Comprehensive Cancer Center | New Haven | Connecticut | 06520-8028 | — |
| Walter Reed Army Medical Center | Washington D.C. | District of Columbia | 20307-5000 | — |
| Shands Hospital and Clinics, University of Florida | Gainesville | Florida | 32610-100277 | — |
| Nemours Children's Clinic | Jacksonville | Florida | 32207 | — |
| Sylvester Cancer Center, University of Miami | Miami | Florida | 33136 | — |
| Miami Children's Hospital | Miami | Florida | 33155 | — |
| Baptist Hospital of Miami | Miami | Florida | 33176-2197 | — |
| Walt Disney Memorial Cancer Institute | Orlando | Florida | 32803 | — |
| CCOP - Florida Pediatric | Tampa | Florida | 33682-7757 | — |
| St. Mary's Hospital | West Palm Beach | Florida | 33407 | — |
| Emory University Hospital - Atlanta | Atlanta | Georgia | 30322 | — |
| Cancer Research Center of Hawaii | Honolulu | Hawaii | 96813 | — |
| Tripler Army Medical Center | Honolulu | Hawaii | 96859-5000 | — |
| Rush-Presbyterian-St. Luke's Medical Center | Chicago | Illinois | 60612 | — |
| Children's Memorial Hospital, Chicago | Chicago | Illinois | 60614 | — |
| Hope Children's Hospital | Oak Lawn | Illinois | 60453 | — |
| Saint Jude Midwest Affiliate | Peoria | Illinois | 61637 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160-7357 | — |
| CCOP - Wichita | Wichita | Kansas | 67214-3882 | — |
| Via Christi Regional Medical Center | Wichita | Kansas | 67214 | — |
| MBCCOP - LSU Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Tulane University School of Medicine | New Orleans | Louisiana | 70112 | — |
| CCOP - Ochsner | New Orleans | Louisiana | 70121 | — |
| Eastern Maine Medical Center | Bangor | Maine | 04401 | — |
| Maine Children's Cancer Program | Portland | Maine | 04101 | — |
| Marlene & Stewart Greenebaum Cancer Center, University of Maryland | Baltimore | Maryland | 21201 | — |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Baltimore | Maryland | 21231-2410 | — |
| Boston Floating Hospital Infants and Children | Boston | Massachusetts | 02111 | — |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| University of Massachusetts Memorial Medical Center | Worcester | Massachusetts | 01655 | — |
| Children's Hospital of Michigan | Detroit | Michigan | 48201 | — |
| St. John's Hospital and Medical Center | Detroit | Michigan | 48236 | — |
| Hurley Medical Center | Flint | Michigan | 48503 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216-4505 | — |
| Keesler Medical Center - Keesler AFB | Keesler Air Force Base | Mississippi | 39534-2576 | — |
| University of Missouri-Columbia Hospital and Clinics | Columbia | Missouri | 65212 | — |
| Cardinal Glennon Children's Hospital | St Louis | Missouri | 63104 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Norris Cotton Cancer Center | Lebanon | New Hampshire | 03756-0002 | — |
| CCOP - Northern New Jersey | Hackensack | New Jersey | 07601 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| University of New Mexico School of Medicine | Albuquerque | New Mexico | 87131 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263-0001 | — |
| Schneider Children's Hospital | New Hyde Park | New York | 11042 | — |
| Mount Sinai School of Medicine | New York | New York | 10029 | — |
| University of Rochester Cancer Center | Rochester | New York | 14642 | — |
| State University of New York Health Sciences Center - Stony Brook | Stony Brook | New York | 11790-7775 | — |
| State University of New York - Upstate Medical University | Syracuse | New York | 13210 | — |
| Mission Saint Joseph's Health System | Asheville | North Carolina | 28801 | — |
| Carolinas Medical Center | Charlotte | North Carolina | 28232-2861 | — |
| Presbyterian Healthcare | Charlotte | North Carolina | 28233-3549 | — |
| Duke Comprehensive Cancer Center | Durham | North Carolina | 27710 | — |
| East Carolina University School of Medicine | Greenville | North Carolina | 27858-4354 | — |
| Comprehensive Cancer Center at Wake Forest University | Winston-Salem | North Carolina | 27157-1082 | — |
| Oklahoma Memorial Hospital | Oklahoma City | Oklahoma | 73126-0307 | — |
| Natalie Warren Bryant Cancer Center | Tulsa | Oklahoma | 74136 | — |
| CCOP - Columbia River Program | Portland | Oregon | 97213 | — |
| Legacy Emanuel Hospital and Health Center | Portland | Oregon | 97227 | — |
| St. Christopher's Hospital for Children | Philadelphia | Pennsylvania | 19134-1095 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425-0721 | — |
| Children's Hospital of Greenville Hospital System | Greenville | South Carolina | 29605 | — |
| James H. Quillen College of Medicine | Johnson City | Tennessee | 37614-0622 | — |
| Saint Jude Children's Research Hospital | Memphis | Tennessee | 38105-2794 | — |
| Medical City Dallas Hospital | Dallas | Texas | 75230 | — |
| Simmons Cancer Center - Dallas | Dallas | Texas | 75235-9154 | — |
| Cook Children's Medical Center - Fort Worth | Fort Worth | Texas | 76104 | — |
| University of Texas Medical Branch | Galveston | Texas | 77555-0209 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| San Antonio Military Pediatric Cancer and Blood Disorders Center | Lackland Air Force Base | Texas | 78236-5300 | — |
| MBCCOP - South Texas Pediatric | San Antonio | Texas | 78229-3900 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78284-7811 | — |
| Scott and White Clinic | Temple | Texas | 76508 | — |
| Vermont Cancer Center | Burlington | Vermont | 05401-3498 | — |
| Cancer Center at the University of Virginia | Charlottesville | Virginia | 22908 | — |
| Inova Fairfax Hospital | Falls Church | Virginia | 22042-3300 | — |
| Naval Medical Center, Portsmouth | Portsmouth | Virginia | 23708-2197 | — |
| Massey Cancer Center | Richmond | Virginia | 23298-0037 | — |
| Carilion Roanoke Community Hospital | Roanoke | Virginia | 24029 | — |
| Madigan Army Medical Center | Tacoma | Washington | 98431-5000 | — |
| West Virginia University Medical School-Charleston | Charleston | West Virginia | 25304 | — |
| West Virginia University Hospitals | Morgantown | West Virginia | 26506-9300 | — |
| St. Vincent Hospital | Green Bay | Wisconsin | 54307-3508 | — |
| Midwest Children's Cancer Center | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 13 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00003811, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 4, 2013 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00003811 live on ClinicalTrials.gov.