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Completed Phase 3 Interventional

Lymph Node Removal in Treating Patients With Stage I or Stage II Non-small Cell Lung Cancer

ClinicalTrials.gov ID: NCT00003831

Public ClinicalTrials.gov record NCT00003831. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 10:38 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Randomized Trial of Mediastinal Lymph Node Sampling Versus Complete Lymphadenectomy During Pulmonary Resection in the Patient With N0 and N1 (Less Than Hilar) Non-Small Cell Carcinoma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Surgical removal of all lymph nodes in the chest may kill cancer cells that have spread from tumors in the lung. It is not yet known whether complete removal of all lymph nodes in the chest is more effective than removal of selected lymph nodes in treating patients who have stage I or stage II non-small cell lung cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of complete removal of all lymph nodes in the chest with that of selected removal of lymph nodes during lung cancer surgery in treating patients who have stage I or stage II non-small cell lung cancer.

Study identification

NCT ID
NCT00003831
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Enrollment
1,023 participants

Conditions and interventions

Conditions

Interventions

Procedure

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 30, 1999
Primary completion
Feb 28, 2006
Completion
Dec 31, 2010
Last update posted
Jul 13, 2016

1999 – 2011

United States locations

U.S. sites
70
U.S. states
25
U.S. cities
52
Facility City State ZIP Site status
Mobile Infirmary Medical Center Mobile Alabama 36640-0460
Cedars-Sinai Comprehensive Cancer Center at Cedars-Sinai Medical Center Los Angeles California 90048
Chao Family Comprehensive Cancer Center at University of California Irvine Cancer Center Orange California 92868
Huntington Cancer Center at Huntington Hospital Pasadena California 91105
UCSF Comprehensive Cancer Center San Francisco California 94143-0128
Stanford University Medical Center Stanford California 94305-5408
Veterans Affairs Medical Center - Gainesville Gainesville Florida 32608-1197
Shands Cancer Center at the University of Florida Gainesville Florida 32610-0342
Holmes Regional Medical Center Melbourne Florida 32901
Jackson Memorial Hospital Miami Florida 33136
Emory University School of Medicine Atlanta Georgia 30322
Medical Center of Central Georgia Macon Georgia 31201
University of Chicago Cancer Research Center Chicago Illinois 60637-1470
Alexian Brothers Medical Center Elk Grove Village Illinois 60007
Loyola University Medical Center Maywood Illinois 60153
Edward Hospital Cancer Center Naperville Illinois 60540
St. John's Hospital Springfield Illinois 62701
Southern Illinois University School of Medicine Springfield Illinois 62702
Central Baptist Hospital Lexington Kentucky 40503
Jewish Hospital Louisville Kentucky 40202-1886
Medical Center of Southwest Louisiana Lafayette Louisiana 70506
Massachusetts General Hospital Cancer Center Boston Massachusetts 02114-2620
Rhode Island Hospital Boston Massachusetts 02114-2620
Beth Israel Deaconess Medical Center Boston Massachusetts 02215
Hurley Medical Center Flint Michigan 48503
William Beaumont Hospital - Royal Oak Royal Oak Michigan 48073
St. Luke's Hospital Duluth Minnesota 55805-2193
Veterans Affairs Medical Center - Minneapolis Minneapolis Minnesota 55417
Mayo Clinic Cancer Center Rochester Minnesota 55905
Ellis Fischel Cancer Center at University of Missouri - Columbia Columbia Missouri 65203
Barnes-Jewish Hospital St Louis Missouri 63110
Veterans Affairs Medical Center - Omaha Omaha Nebraska 68105
Creighton University School of Medicine Omaha Nebraska 68131
Englewood Hospital Oncology Program Englewood New Jersey 07631
Valley Hospital Ridgewood New Jersey 07450
Roswell Park Cancer Institute Buffalo New York 14263-0001
Louis Busch Hager Cancer Center at Mary Imogene Bassett Hospital Cooperstown New York 13326
Memorial Sloan-Kettering Cancer Center New York New York 10021
New York Weill Cornell Cancer Center at Cornell University New York New York 10021
James P. Wilmot Cancer Center at University of Rochester Medical Center Rochester New York 14642
Long Island Cancer Center at Stony Brook University Hospital Stony Brook New York 11790-8191
Trinity Hospital Minot North Dakota 58701
Veterans Affairs Medical Center - Cincinnati Cincinnati Ohio 45220-2288
Tri-Health Good Samaritan Hospital Cincinnati Ohio 45220
Charles M. Barrett Cancer Center at University Hospital Cincinnati Ohio 45267-0558
Ireland Cancer Center Cleveland Ohio 44106-5065
Earle A. Chiles Research Institute at Providence Portland Medical Center Portland Oregon 97213-2967
Westmoreland Regional Hospital Greensburg Pennsylvania 15601-2282
Jameson Memorial Hospital New Castle Pennsylvania 16105
Abramson Cancer Center at University of Pennsylvania Medical Center Philadelphia Pennsylvania 19104-4283
Kimmel Cancer Center at Thomas Jefferson University - Philadelphia Philadelphia Pennsylvania 19107-5541
Fox Chase Cancer Center Philadelphia Pennsylvania 19111-2497
Temple University Hospital Philadelphia Pennsylvania 19140
Allegheny General Hospital Pittsburgh Pennsylvania 15212-4772
University of Pittsburg Medical Center - Shadyside Hospital Pittsburgh Pennsylvania 15213-2582
Presbyterian-University Hospital Pittsburgh Pennsylvania 15213
UPMC St. Margaret Pittsburgh Pennsylvania 15215
Western Pennsylvania Hospital Pittsburgh Pennsylvania 15224
St. Clair Memorial Hospital Pittsburgh Pennsylvania 15243-1899
Lankenau Cancer Center at Lankenau Hospital Wynnewood Pennsylvania 19096
Saint Thomas Hospital Nashville Tennessee 37205
University of Texas - MD Anderson Cancer Center Houston Texas 77030-4009
LDS Hospital Salt Lake City Utah 84143
Cancer Center at the University of Virginia Charlottesville Virginia 22908
Massey Cancer Center Richmond Virginia 23298-0037
Swedish Cancer Institute at Swedish Medical Center - First Hill Campus Seattle Washington 98104
University of Washington Medical Center Seattle Washington 98195-6310
Veterans Affairs Medical Center - Seattle Seattle Washington 98195-6310
West Virginia University Hospitals Morgantown West Virginia 26506-9300
University of Wisconsin Comprehensive Cancer Center Madison Wisconsin 53792-7375

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00003831, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 13, 2016 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00003831 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →