Topotecan in Treating Patients With Relapsed Small Cell Lung Cancer
Public ClinicalTrials.gov record NCT00003917. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
An Open Label, Multicenter, Randomized, Phase III Comparator Study of Oral Topotecan Versus Intravenous Topotecan for Second Line Therapy in Patients With Small Cell Lung Cancer Who Have Relapsed Greater Than or Equal to 90 Days After Completion of First Line Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if topotecan is more effective given by infusion or by mouth. PURPOSE: Randomized phase III trial to compare the effectiveness of topotecan given by infusion with that of topotecan given by mouth in treating patients who have small cell lung cancer that has relapsed following previous therapy.
Study identification
- NCT ID
- NCT00003917
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 4 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 1999 (Type not available)
- Primary completion
- Nov 2001 (Actual)
- Completion
- Nov 2001 (Actual)
- Last update posted
- Jan 9, 2014
1999 – 2001
United States locations
- U.S. sites
- 53
- U.S. states
- 24
- U.S. cities
- 51
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Comprehensive Cancer Center | Birmingham | Alabama | 35294 | — |
| Veterans Affairs Medical Center - Phoenix (Hayden) | Phoenix | Arizona | 85012 | — |
| Comprehensive Blood and Cancer Center | Bakersfield | California | 93309 | — |
| Pacific Coast Hematology/Oncology Medical Group | Fountain Valley | California | 92708 | — |
| Scripps Clinic | La Jolla | California | 92037 | — |
| Veterans Affairs Medical Center - West Los Angeles | Los Angeles | California | 90073 | — |
| Southwest Cancer Care | Poway | California | 92064 | — |
| University of California Davis Cancer Center | Sacramento | California | 95817 | — |
| Kaiser Permanente-Southern California Permanente Medical Group | San Diego | California | 92120 | — |
| Sidney Kimmel Cancer Center | San Diego | California | 92121 | — |
| Oncology Clinic, P.C. | Colorado Springs | Colorado | 80909 | — |
| Shands Cancer Center | Gainesville | Florida | 32610 | — |
| Baptist Regional Cancer Institute - Jacksonville | Jacksonville | Florida | 32207 | — |
| Oncology-Hematology Group of South Florida | Miami | Florida | 33176 | — |
| Baptist Hospital- Pensacola | Pensacola | Florida | 32522 | — |
| H. Lee Moffitt Cancer Center and Research Institute | Tampa | Florida | 33612 | — |
| Medical College of Georgia Hospital and Clinics | Augusta | Georgia | 30912-3620 | — |
| Evanston Northwestern Health Care | Evanston | Illinois | 60201 | — |
| Veterans Affairs Medical Center - Hines (Hines Junior VA Hospital) | Hines | Illinois | 60141 | — |
| Oncology and Hematology Associates, Inc. | Indianapolis | Indiana | 46219 | — |
| Louisiana Oncology Associates | Lafayette | Louisiana | 70506 | — |
| Alton Ochsner Medical Foundation Hospital | New Orleans | Louisiana | 70121 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| St. Joseph Mercy Hospital | Pontiac | Michigan | 48341-2985 | — |
| CCOP - Metro-Minnesota | Saint Louis Park | Minnesota | 55416 | — |
| St. John's Mercy Medical Center | St Louis | Missouri | 63141 | — |
| Cooper Cancer Institute | Camden | New Jersey | 08103 | — |
| St. Barnabas Medical Center | Livingston | New Jersey | 07039 | — |
| Cooper Hospital/University Medical Center | Voorhees Township | New Jersey | 08043 | — |
| Santa Fe Hematology/Oncology | Santa Fe | New Mexico | 87505 | — |
| Rochester General Hospital | Rochester | New York | 14621 | — |
| State University of New York - Upstate Medical University | Syracuse | New York | 13210 | — |
| Salem Research | Winston-Salem | North Carolina | 27103 | — |
| Comprehensive Cancer Center of Wake Forest University Baptist Medical Center | Winston-Salem | North Carolina | 27157-1082 | — |
| Ireland Cancer Center | Cleveland | Ohio | 44106-5065 | — |
| Penn State Geisinger Cancer Center | Hershey | Pennsylvania | 17033 | — |
| Central Pennsylvania Hematology & Medical Oncology Associates, PC | Lemoyne | Pennsylvania | 17043-1440 | — |
| University of Pittsburgh Cancer Institute | Pittsburgh | Pennsylvania | 15213 | — |
| Reading Hospital and Medical Center | Reading | Pennsylvania | 19612-6052 | — |
| Brown University Oncology Group | Providence | Rhode Island | 02912 | — |
| Cancer Centers of the Carolinas | Greenville | South Carolina | 29605 | — |
| Spartanburg Regional Healthcare System | Spartanburg | South Carolina | 29303 | — |
| Baptist Regional Cancer Center - Knoxville | Knoxville | Tennessee | 37901 | — |
| Sarah Cannon-Minnie Pearl Cancer Center | Nashville | Tennessee | 37203 | — |
| Texas Cancer Care | Fort Worth | Texas | 76104 | — |
| University of Texas Medical Branch | Galveston | Texas | 77555-0209 | — |
| University of Texas - MD Anderson Cancer Center | Houston | Texas | 77030-4009 | — |
| Joe Arrington Cancer Center | Lubbock | Texas | 79410 | — |
| Scott and White Memorial Hospital | Temple | Texas | 76508 | — |
| Office of Michael E. Lee | Norfolk | Virginia | 23502 | — |
| Hematology & Oncology Associates of Virginia | Richmond | Virginia | 23226 | — |
| Oncology and Hematology Associates of Southwest Virginia, Inc. | Roanoke | Virginia | 24014 | — |
| Waukesha Memorial Hospital | Waukesha | Wisconsin | 53188 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00003917, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 9, 2014 · Synced Nov 4, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00003917 live on ClinicalTrials.gov.