ClinicalTrials.gov record
Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma
ClinicalTrials.gov ID: NCT00003937
Public ClinicalTrials.gov record NCT00003937. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 14, 2026, 9:18 PM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Protocol for Patients With Newly-Diagnosed Non-Metastatic Osteosarcoma - A POG/CCG Pilot Intergroup Study
Study identification
- NCT ID
- NCT00003937
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Children's Oncology Group
- Network
- Enrollment
- 253 participants
Conditions and interventions
Conditions
Interventions
- cisplatin Drug
- conventional surgery Procedure
- dexrazoxane hydrochloride Drug
- doxorubicin hydrochloride Drug
- etoposide Drug
- ifosfamide Drug
- methotrexate Drug
Drug · Procedure
Eligibility (public fields only)
- Age range
- Up to 30 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 31, 1999
- Primary completion
- Feb 29, 2004
- Completion
- May 31, 2008
- Last update posted
- Aug 4, 2014
1999 – 2008
United States locations
- U.S. sites
- 132
- U.S. states
- 41
- U.S. cities
- 100
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham Comprehensive Cancer Center | Birmingham | Alabama | 35294-3300 | — |
| MBCCOP - Gulf Coast | Mobile | Alabama | 36688 | — |
| Arizona Cancer Center | Tucson | Arizona | 85724 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| University of California San Diego Cancer Center | La Jolla | California | 92093-0658 | — |
| Long Beach Memorial Medical Center | Long Beach | California | 90806 | — |
| Children's Hospital Los Angeles | Los Angeles | California | 90027-0700 | — |
| Jonsson Comprehensive Cancer Center, UCLA | Los Angeles | California | 90095-1781 | — |
| Children's Hospital of Orange County | Orange | California | 92868 | — |
| Lucile Packard Children's Hospital at Stanford | Palo Alto | California | 94304 | — |
| Sutter Cancer Center | Sacramento | California | 95816 | — |
| University of California Davis Medical Center | Sacramento | California | 95817 | — |
| Kaiser Permanente-Southern California Permanente Medical Group | San Diego | California | 92120 | — |
| Children's Hospital and Health Center | San Diego | California | 92123-4282 | — |
| UCSF Cancer Center and Cancer Research Institute | San Francisco | California | 94143-0128 | — |
| Kaiser Permanente Medical Center - Santa Clara | Santa Clara | California | 95051-5386 | — |
| David Grant Medical Center | Travis Air Force Base | California | 94535 | — |
| Children's Hospital of Denver | Denver | Colorado | 80218 | — |
| Yale Comprehensive Cancer Center | New Haven | Connecticut | 06520-8028 | — |
| Children's National Medical Center | Washington D.C. | District of Columbia | 20010-2970 | — |
| Walter Reed Army Medical Center | Washington D.C. | District of Columbia | 20307-5000 | — |
| Shands Hospital and Clinics, University of Florida | Gainesville | Florida | 32610-100277 | — |
| Nemours Children's Clinic | Jacksonville | Florida | 32207 | — |
| Sylvester Cancer Center, University of Miami | Miami | Florida | 33136 | — |
| Miami Children's Hospital | Miami | Florida | 33155 | — |
| Baptist Hospital of Miami | Miami | Florida | 33176-2197 | — |
| Walt Disney Memorial Cancer Institute | Orlando | Florida | 32803 | — |
| All Children's Hospital | St. Petersburg | Florida | 33701 | — |
| CCOP - Florida Pediatric | Tampa | Florida | 33682-7757 | — |
| St. Mary's Hospital | West Palm Beach | Florida | 33407 | — |
| Emory University Hospital - Atlanta | Atlanta | Georgia | 30322 | — |
| Cancer Research Center of Hawaii | Honolulu | Hawaii | 96813 | — |
| Tripler Army Medical Center | Honolulu | Hawaii | 96859-5000 | — |
| Rush-Presbyterian-St. Luke's Medical Center | Chicago | Illinois | 60612 | — |
| Children's Memorial Hospital, Chicago | Chicago | Illinois | 60614 | — |
| University of Chicago Cancer Research Center | Chicago | Illinois | 60637-1470 | — |
| Hope Children's Hospital | Oak Lawn | Illinois | 60453 | — |
| CCOP - Illinois Oncology Research Association | Peoria | Illinois | 61602 | — |
| Saint Jude Midwest Affiliate | Peoria | Illinois | 61637 | — |
| Indiana University Cancer Center | Indianapolis | Indiana | 46202-5289 | — |
| Holden Comprehensive Cancer Center at The University of Iowa | Iowa City | Iowa | 52242-1009 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160-7357 | — |
| CCOP - Wichita | Wichita | Kansas | 67214-3882 | — |
| Via Christi Regional Medical Center | Wichita | Kansas | 67214 | — |
| MBCCOP - LSU Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Tulane University School of Medicine | New Orleans | Louisiana | 70112 | — |
| CCOP - Ochsner | New Orleans | Louisiana | 70121 | — |
| Eastern Maine Medical Center | Bangor | Maine | 04401 | — |
| Maine Children's Cancer Program | Portland | Maine | 04101 | — |
| Marlene & Stewart Greenebaum Cancer Center, University of Maryland | Baltimore | Maryland | 21201 | — |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Baltimore | Maryland | 21231-2410 | — |
| Boston Floating Hospital Infants and Children | Boston | Massachusetts | 02111 | — |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| University of Massachusetts Memorial Medical Center | Worcester | Massachusetts | 01655 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109-0752 | — |
| Children's Hospital of Michigan | Detroit | Michigan | 48201 | — |
| St. John's Hospital and Medical Center | Detroit | Michigan | 48236 | — |
| Hurley Medical Center | Flint | Michigan | 48503 | — |
| CCOP - Kalamazoo | Kalamazoo | Michigan | 49007-3731 | — |
| University of Minnesota Cancer Center | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic Cancer Center | Rochester | Minnesota | 55905 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216-4505 | — |
| Keesler Medical Center - Keesler AFB | Keesler Air Force Base | Mississippi | 39534-2576 | — |
| University of Missouri-Columbia Hospital and Clinics | Columbia | Missouri | 65212 | — |
| Children's Mercy Hospital | Kansas City | Missouri | 64108 | — |
| Cardinal Glennon Children's Hospital | St Louis | Missouri | 63104 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198-3330 | — |
| Norris Cotton Cancer Center | Lebanon | New Hampshire | 03756-0002 | — |
| CCOP - Northern New Jersey | Hackensack | New Jersey | 07601 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Cancer Institute of New Jersey | New Brunswick | New Jersey | 08901 | — |
| University of New Mexico School of Medicine | Albuquerque | New Mexico | 87131 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263-0001 | — |
| Schneider Children's Hospital | New Hyde Park | New York | 11042 | — |
| NYU School of Medicine's Kaplan Comprehensive Cancer Center | New York | New York | 10016 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10021 | — |
| Mount Sinai School of Medicine | New York | New York | 10029 | — |
| Herbert Irving Comprehensive Cancer Center | New York | New York | 10032 | — |
| University of Rochester Cancer Center | Rochester | New York | 14642 | — |
| State University of New York Health Sciences Center - Stony Brook | Stony Brook | New York | 11790-7775 | — |
| State University of New York - Upstate Medical University | Syracuse | New York | 13210 | — |
| Mission Saint Joseph's Health System | Asheville | North Carolina | 28801 | — |
| Lineberger Comprehensive Cancer Center, UNC | Chapel Hill | North Carolina | 27599-7295 | — |
| Carolinas Medical Center | Charlotte | North Carolina | 28232-2861 | — |
| Presbyterian Healthcare | Charlotte | North Carolina | 28233-3549 | — |
| Duke Comprehensive Cancer Center | Durham | North Carolina | 27710 | — |
| East Carolina University School of Medicine | Greenville | North Carolina | 27858-4354 | — |
| Comprehensive Cancer Center at Wake Forest University | Winston-Salem | North Carolina | 27157-1082 | — |
| Veterans Affairs Medical Center - Fargo | Fargo | North Dakota | 58102 | — |
| CCOP - Merit Care Hospital | Fargo | North Dakota | 58122 | — |
| Children's Hospital Medical Center - Cincinnati | Cincinnati | Ohio | 45229-3039 | — |
| Ireland Cancer Center | Cleveland | Ohio | 44106-5065 | — |
| Children's Hospital of Columbus | Columbus | Ohio | 43205-2696 | — |
| Oklahoma Memorial Hospital | Oklahoma City | Oklahoma | 73126-0307 | — |
| Natalie Warren Bryant Cancer Center | Tulsa | Oklahoma | 74136 | — |
| Doernbecher Children's Hospital | Portland | Oregon | 97201-3098 | — |
| CCOP - Columbia River Program | Portland | Oregon | 97213 | — |
| Legacy Emanuel Hospital and Health Center | Portland | Oregon | 97227 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| St. Christopher's Hospital for Children | Philadelphia | Pennsylvania | 19134-1095 | — |
| Children's Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425-0721 | — |
| Children's Hospital of Greenville Hospital System | Greenville | South Carolina | 29605 | — |
| James H. Quillen College of Medicine | Johnson City | Tennessee | 37614-0622 | — |
| Saint Jude Children's Research Hospital | Memphis | Tennessee | 38105-2794 | — |
| Vanderbilt-Ingram Cancer Center | Nashville | Tennessee | 37232-6838 | — |
| Texas Oncology P.A. | Dallas | Texas | 75230-2503 | — |
| Medical City Dallas Hospital | Dallas | Texas | 75230 | — |
| Simmons Cancer Center - Dallas | Dallas | Texas | 75235-9154 | — |
| University of Texas Medical Branch | Galveston | Texas | 77555-0209 | — |
| University of Texas - MD Anderson Cancer Center | Houston | Texas | 77030-4009 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| San Antonio Military Pediatric Cancer and Blood Disorders Center | Lackland Air Force Base | Texas | 78236-5300 | — |
| MBCCOP - South Texas Pediatric | San Antonio | Texas | 78229-3900 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78284-7811 | — |
| Scott and White Clinic | Temple | Texas | 76508 | — |
| Vermont Cancer Center | Burlington | Vermont | 05401-3498 | — |
| Cancer Center at the University of Virginia | Charlottesville | Virginia | 22908 | — |
| Inova Fairfax Hospital | Falls Church | Virginia | 22042-3300 | — |
| Naval Medical Center, Portsmouth | Portsmouth | Virginia | 23708-2197 | — |
| Massey Cancer Center | Richmond | Virginia | 23298-0037 | — |
| Carilion Roanoke Community Hospital | Roanoke | Virginia | 24029 | — |
| Children's Hospital and Regional Medical Center - Seattle | Seattle | Washington | 98105 | — |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109-1024 | — |
| Madigan Army Medical Center | Tacoma | Washington | 98431-5000 | — |
| West Virginia University Medical School-Charleston | Charleston | West Virginia | 25304 | — |
| West Virginia University Hospitals | Morgantown | West Virginia | 26506-9300 | — |
| St. Vincent Hospital | Green Bay | Wisconsin | 54307-3508 | — |
| University of Wisconsin Comprehensive Cancer Center | Madison | Wisconsin | 53792-6164 | — |
| Midwest Children's Cancer Center | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00003937, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 4, 2014 · Synced May 14, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00003937 live on ClinicalTrials.gov.