Interleukin-2 Plus Histamine Dihydrochloride in Treating Patients With Acute Myeloid Leukemia
Public ClinicalTrials.gov record NCT00003991. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Multi-Center, Randomized Open-Label Study to Evaluate the Safety and Efficacy of Immunotherapy With Subcutaneous Maxamine (Histamine Dihydrochloride) Plus Proleukin (Interleukin-2) Versus No Treatment (Standard of Care) in Patients With Acute Myeloid Leukemia in First or Subsequent Complete Remission (CR)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Interleukin-2 may stimulate a person's white blood cells to kill acute myeloid leukemia cells. Histamine dihydrochloride may prolong remission and reduce the risk of relapse in patients with acute myeloid leukemia in remission. PURPOSE: Randomized phase III trial to determine the effectiveness of interleukin-2 plus histamine dihydrochloride in treating patients who have acute myeloid leukemia that is in remission following previous therapy.
Study identification
- NCT ID
- NCT00003991
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 360 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 1998 (Type not available)
- Primary completion
- Not listed
- Completion
- Aug 2011 (Actual)
- Last update posted
- Nov 6, 2013
1998 – 2011
United States locations
- U.S. sites
- 32
- U.S. states
- 17
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Comprehensive Cancer Center | Birmingham | Alabama | 35294 | — |
| Arizona Cancer Center | Tucson | Arizona | 85724 | — |
| Scripps Clinic | La Jolla | California | 92037 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| Kaiser Permanente-Southern California Permanente Medical Group | San Diego | California | 92120 | — |
| Sidney Kimmel Cancer Center | San Diego | California | 92121 | — |
| Pacific Hematology/Oncology | San Francisco | California | 94115 | — |
| Bethesda Bone Marrow Stem Cell Transplant Institute | Boynton Beach | Florida | 33473 | — |
| University of Florida Health Science Center - Jacksonville | Jacksonville | Florida | 32209 | — |
| Emory University Hospital - Atlanta | Atlanta | Georgia | 30322 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160-7357 | — |
| Oncology and Hematology Associates | Westwood | Kansas | 66205 | — |
| Maine Center for Cancer Medicine and Blood Disorders | Scarborough | Maine | 04074 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Providence Hospital Cancer Center | Southfield | Michigan | 48075 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Nevada Cancer Center | Las Vegas | Nevada | 89106 | — |
| Nevada Medical Group-Internal Medicine | Reno | Nevada | 89502 | — |
| University of New Mexico Cancer Research & Treatment Center | Albuquerque | New Mexico | 87131 | — |
| New York Presbyterian Hospital - Cornell Campus | New York | New York | 10021 | — |
| University of Rochester Cancer Center | Rochester | New York | 14642 | — |
| Our Lady of Mercy Medical Center | The Bronx | New York | 10466 | — |
| New York Medical College | Valhalla | New York | 10595 | — |
| Ireland Cancer Center | Cleveland | Ohio | 44106-5065 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73190 | — |
| University of Pennsylvania Cancer Center | Philadelphia | Pennsylvania | 19104 | — |
| Western Pennsylvania Hospital | Pittsburgh | Pennsylvania | 15224 | — |
| West Clinic, P.C. | Memphis | Tennessee | 38117 | — |
| Boston Cancer Group | Memphis | Tennessee | 38119 | — |
| Baylor University Medical Center | Dallas | Texas | 75246 | — |
| Cancer Care Institute of South Texas | San Antonio | Texas | 78229 | — |
| South Texas Cancer Institute | San Antonio | Texas | 78229 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 86 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00003991, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 6, 2013 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00003991 live on ClinicalTrials.gov.