ClinicalTrials.gov record
Completed Phase 3 Interventional

Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Neuroblastoma

ClinicalTrials.gov ID: NCT00004188

Public ClinicalTrials.gov record NCT00004188. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 11, 2026, 10:26 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized Study of Purged Versus Unpurged Peripheral Blood Stem Cell Transplant Following Dose Intensive Induction Therapy for High Risk Neuroblastoma

Study identification

NCT ID
NCT00004188
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Children's Oncology Group
Network
Enrollment
495 participants

Conditions and interventions

Conditions

Interventions

  • autologous bone marrow transplantation Procedure
  • bone marrow ablation with stem cell support Procedure
  • carboplatin Drug
  • cisplatin Drug
  • conventional surgery Procedure
  • cyclophosphamide Drug
  • doxorubicin hydrochloride Drug
  • etoposide Drug
  • filgrastim Biological
  • isotretinoin Drug
  • melphalan Drug
  • peripheral blood stem cell transplantation Procedure
  • radiation therapy Radiation
  • topotecan hydrochloride Drug
  • vincristine sulfate Drug

Procedure · Drug · Biological + 1 more

Eligibility (public fields only)

Age range
Up to 30 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 31, 2001
Primary completion
Sep 30, 2007
Completion
Not listed
Last update posted
May 16, 2013

Started 2001

United States locations

U.S. sites
86
U.S. states
37
U.S. cities
79
Facility City State ZIP Site status
Comprehensive Cancer Center at University of Alabama at Birmingham Birmingham Alabama 35294
Phoenix Children's Hospital Phoenix Arizona 85016-7710
Southern California Permanente Medical Group Downey California 90242-2814
Loma Linda University Cancer Institute at Loma Linda University Medical Center Loma Linda California 92354
Jonathan Jaques Children's Cancer Center at Miller Children's Hospital Long Beach California 90801
Children's Hospital Los Angeles Los Angeles California 90027
Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center Los Angeles California 90048-1865
Children's Hospital Central California Madera California 93638-8762
Kaiser Permanente Medical Center - Oakland Sacramento California 95825
Children's Hospital and Health Center - San Diego San Diego California 92123-4282
UCSF Comprehensive Cancer Center San Francisco California 94115
Stanford Cancer Center at Stanford University Medical Center Stanford California 94305
Children's Hospital Cancer Center Denver Colorado 80218-1088
Carole and Ray Neag Comprehensive Cancer Center at the University of Connecticut Health Center Farmington Connecticut 06360-2875
Children's National Medical Center Washington D.C. District of Columbia 20010-2970
Broward General Medical Center Cancer Center Fort Lauderdale Florida 33316
Lee Cancer Care of Lee Memorial Health System Fort Myers Florida 33901
University of Florida Shands Cancer Center Gainesville Florida 32610-0232
Memorial Cancer Institute at Memorial Regional Hospital Hollywood Florida 33021
All Children's Hospital St. Petersburg Florida 33701
St. Joseph's Cancer Institute at St. Joseph's Hospital Tampa Florida 33607
Kaplan Cancer Center at St. Mary's Medical Center West Palm Beach Florida 33407
University of Illinois at Chicago Cancer Center Chicago Illinois 60612-7243
Children's Memorial Hospital - Chicago Chicago Illinois 60614
Southern Illinois University School of Medicine Springfield Illinois 62794-9620
Indiana University Cancer Center Indianapolis Indiana 46202-5289
St. Vincent Indianapolis Hospital Indianapolis Indiana 46260
Blank Children's Hospital Des Moines Iowa 50309
Holden Comprehensive Cancer Center at University of Iowa Iowa City Iowa 52242-1083
Markey Cancer Center at University of Kentucky Chandler Medical Center Lexington Kentucky 40536-0084
Kosair Children's Hospital Louisville Kentucky 40232
CancerCare of Maine at Eastern Maine Medial Center Bangor Maine 04401
Alvin and Lois Lapidus Cancer Institute at Sinai Hospital Baltimore Maryland 21215
Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute Boston Massachusetts 02115
C.S. Mott Children's Hospital at University of Michigan Ann Arbor Michigan 48109-0238
Spectrum Health Cancer Care - Butterworth Campus Grand Rapids Michigan 49503-2560
Van Elslander Cancer Center at St. John Hospital and Medical Center Grosse Pointe Woods Michigan 48236
CCOP - Kalamazoo Kalamazoo Michigan 49007-5341
Breslin Cancer Center at Ingham Regional Medical Center Lansing Michigan 48910
Children's Hospital of Minnesota - Minneapolis Minneapolis Minnesota 55404
Fairview University Medical Center - University Campus Minneapolis Minnesota 55455
Children's Mercy Hospital Kansas City Missouri 64108
Siteman Cancer Center at Barnes-Jewish Hospital St Louis Missouri 63110
Children's Hospital of Omaha Omaha Nebraska 68114-4113
UNMC Eppley Cancer Center at the University of Nebraska Medical Center Omaha Nebraska 68198-3330
Sunrise Hospital and Medical Center Las Vegas Nevada 89109-2306
Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center Lebanon New Hampshire 03756-0002
Cancer Center at Hackensack University Medical Center Hackensack New Jersey 07601
St. Barnabas Medical Center Livingston New Jersey 07039
Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School New Brunswick New Jersey 08903
Newark Beth Israel Medical Center Newark New Jersey 07112
St. Joseph's Hospital and Medical Center Paterson New Jersey 07503
University of New Mexico Cancer Research and Treatment Center Albuquerque New Mexico 87131-5636
NYU Cancer Institute at New York University Medical Center New York New York 10016
New York Medical College Valhalla New York 10595
Mission Hospitals - Memorial Campus Asheville North Carolina 28801
Blumenthal Cancer Center at Carolinas Medical Center Charlotte North Carolina 28232-2861
Presbyterian Cancer Center at Presbyterian Hospital Charlotte North Carolina 28233-3549
Duke Comprehensive Cancer Center Durham North Carolina 27710
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229-3039
Cleveland Clinic Taussig Cancer Center Cleveland Ohio 44195-5217
Columbus Children's Hospital Columbus Ohio 43205-2696
Children's Medical Center - Dayton Dayton Ohio 45404-1815
Toledo Hospital Toledo Ohio 43606
Medical College of Ohio Cancer Institute Toledo Ohio 43614
Cancer Institute at Oregon Health and Science University Portland Oregon 97239-3098
Children's Hospital of Pittsburgh Pittsburgh Pennsylvania 15213
Rhode Island Hospital Providence Rhode Island 02903
Palmetto Health South Carolina Cancer Center Columbia South Carolina 29203
Sioux Valley Hospital and University of South Dakota Medical Center Sioux Falls South Dakota 57117-5039
East Tennessee Children's Hospital Knoxville Tennessee 37916
Texas Tech University Health Sciences Center School of Medicine Amarillo Texas 79106
Children's Hospital of Austin Austin Texas 78701
Cook Children's Medical Center - Fort Worth Fort Worth Texas 76104-9958
Covenant Children's Hospital Lubbock Texas 79410
University of Texas Health Science Center at San Antonio San Antonio Texas 78284-7811
Fletcher Allen Health Care - University Health Center Campus Burlington Vermont 05405
Massey Cancer Center at Virginia Commonwealth University Richmond Virginia 23298-0037
Carilion Cancer Center of Western Virginia Roanoke Virginia 24029
Providence Cancer Center at Sacred Heart Medical Center Spokane Washington 99220-2555
Edwards Comprehensive Cancer Center at Cabell Huntington Hospital Huntington West Virginia 25701
Mary Babb Randolph Cancer Center at West Virginia University Hospitals Morgantown West Virginia 26506
St. Vincent Hospital Regional Cancer Center Green Bay Wisconsin 54307-3508
University of Wisconsin Comprehensive Cancer Center Madison Wisconsin 53792-6164
Marshfield Clinic - Marshfield Center Marshfield Wisconsin 54449
Midwest Children's Cancer Center Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00004188, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 16, 2013 · Synced May 11, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00004188 live on ClinicalTrials.gov.

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