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Completed Not applicable Interventional Results available

Carotid Revascularization Endarterectomy Versus Stenting Trial

ClinicalTrials.gov ID: NCT00004732

Public ClinicalTrials.gov record NCT00004732. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 25, 2026, 9:06 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST) is to compare the relatively new procedure of stent-assisted carotid angioplasty (CAS) to the traditional and accepted surgical approach of carotid endarterectomy (CEA) for the treatment of carotid artery stenosis to prevent recurrent strokes in those patients who have had a TIA (transient ischemic attack) or a mild stroke within the past 6 months (symptomatic) and in those patients who have not had any symptoms within the past 6 months (asymptomatic).

Study identification

NCT ID
NCT00004732
Recruitment status
Completed
Study type
Interventional
Phase
Not applicable
Enrollment
2,502 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 2000 (Type not available)
Primary completion
Feb 2011 (Actual)
Completion
Dec 2016 (Actual)
Last update posted
May 17, 2017

2000 – 2016

United States locations

U.S. sites
106
U.S. states
36
U.S. cities
87
Facility City State ZIP Site status
The Board of Trustees of the University of Alabama for the University of Alabama at Birmingham Birmingham Alabama 35294 —
Dignity Health dba St. Joseph's Hospital & Medical Center Phoenix Arizona 85013 —
Mayo Clinic Arizona Scottsdale Arizona 85259 —
The Arizona Board of Regents for the University of Arizona Tucson Arizona 85724 —
Board of Trustees of the University of Arkansas Little Rock Arkansas 72701 —
USC University Hospital & LA County Hospital Los Angeles California 90033 —
The Regents of the University of California Los Angeles California 90095 —
Kaiser Permanente Medical Center San Diego California 92120 —
Northern California Institute for Research and Education San Francisco California 94121 —
Catholic Healthcare West Stockton California 95204 —
Christiana Care Health Services, Inc. Newark Delaware 19718 —
Morton Plant Hospital Clearwater Florida 33756 —
Mayo Clinic Jacksonville Florida 32224 —
Leesburg Medical Center Leesburg Florida 34748 —
Miami Cardiac & Vascular Institute of Baptist Hospital of Miami, Inc. Miami Florida 33187 —
Florida Hospital Neuroscience Institute, a division of Adventist Health System/Sunbelt, Inc. Orlando Florida 32803 —
Orlando Regional Medical Center Orlando Florida 32828 —
University of South Florida Board of Trustees Tampa Florida 33606 —
Piedmont Hospital/Fuqua Heart Center Atlanta Georgia 30309 —
Emory University Atlanta Georgia 30322 —
St. Joseph's of Atlanta Atlanta Georgia 30342 —
St. Joseph's Candler Health System Savannah Georgia 31405 —
Norwestern Memorial Hospital Chicago Illinois 60611 —
Alexian Brothers Specialty Group Elk Grove Village Illinois 60007 —
Loyola University of Chicago Maywood Illinois 60153 —
Peoria Radiology Research and Education Peoria Illinois 61637 —
Prarie Cardiology-St. John's Hospital Springfield Illinois 62794 —
Southern Illinois School of Medicine Springfield Illinois 62794 —
Central Dupage Hospital Winfield Illinois 60190 —
Lutheran Medical Group, LLC, Fort Wayne Indiana 46804 —
Parkview Hospital, Inc. Fort Wayne Indiana 46805 —
St. Vincent's Hospital Indianapolis Indiana 46260 —
Catholic Health Initiatives /Mercy Hospital Center Des Moines Iowa 50314 —
Baptist Healthcare System, Inc. Lexington Kentucky 40504 —
Vascular Surgery Associates Baton Rouge Louisiana 70809 —
Ochsner Foundation Hospital New Orleans Louisiana 70121 —
Anne Arundel Health System Research Institute Annapolis Maryland 21401 —
Johns Hopkins University Baltimore Maryland 21287 —
Adventist Healthcare, Inc. Takoma Park Maryland 20912 —
Massachusetts General Hospital Boston Massachusetts 02114 —
Steward St. Elizabeth's Medical Center of Boston, Inc. Boston Massachusetts 02135 —
Beth Israel Deaconess Medical Center Boston Massachusetts 02215 —
Brigham and Womens Hospital, Inc. Boston Massachusetts 02215 —
Cape Cod Health Care, Inc., Hyannis Massachusetts 02601 —
University of Michigan Ann Arbor Michigan 48109 —
Henry Ford Health System Detroit Michigan 48202 —
St. John Hospital and Medical Center Detroit Michigan 48236 —
Michigan Vascular Research Center Flint Michigan 48507 —
Spectrum Health Hospital Grand Rapids Michigan 49503 —
William Beaumont Hospital Royal Oak Michigan 48075 —
Providence St. John Hopital Southfield Michigan 48075 —
Michigan Heart & Vascular Institute/St. Joseph's Mercy Hospital Ypsilanti Michigan 48197 —
North Memorial Health Care Robbinsdale Minnesota 55422 —
Mayo Clinic Rochester/St. Mary's Rochester Minnesota 55905 —
Mississippi Baptist Medical Center, Inc. Jackson Mississippi 39202 —
Heartland Physician Services, LLC Kansas City Missouri 64114 —
Mercy Hospitals East Communities St Louis Missouri 63141 —
St. Patrick's Hospital International Heart Institute of MT Missoula Montana 59802 —
Dartmouth College and the constituent members of DARTMOUTH HITCHCOCK MEDICAL CENTER Lebanon New Hampshire 03756 —
St. Michael's Medical Center Newark New Jersey 07013 —
Center for Vascular Awareness, Inc. Albany New York 12208 —
Millard Fillmore SUNY Buffalo Buffalo New York 14209 —
NYU School of Medicine New York New York 10016 —
The Feinstein Institute for Medical Research New York New York 10021 —
Weill Medical College of Cornell University New York New York 10021 —
Columbia Presbyterian New York New York 10032 —
St. Francis Hospital Port Washington New York 11050 —
University of Rochester Rochester New York 14642 —
Richmond University Medical Center Staten Island New York 10310 —
Westchester Medical Center Valhalla New York 10595 —
UNC at Chapel Hill Chapel Hill North Carolina 27599 —
The Charlotte-Mecklenburg Hospital Authority Charlotte North Carolina 28203 —
Duke University Medical Center Durham North Carolina 27710 —
Forsyth Radiological Associates Winston-Salem North Carolina 27103 —
Wake Forest University Winston-Salem North Carolina 27157 —
Christ Hospital Cincinnati Ohio 45219 —
University of Cincinnati Cincinnati Ohio 45267 —
The Cleveland Clinic Lerner College Of Medicine of CWRU Cleveland Ohio 44195 —
Midwest Ohio Health Research Institute Columbus Ohio 43214 —
The Toledo Hospital Toledo Ohio 43606 —
University of Toledo Toledo Ohio 43614 —
Oklahoma Foundation for Cardiovascular Research Oklahoma City Oklahoma 73120 —
Rogue Valley Medical Center Medford Oregon 97504 —
Oregon Health Science University Portland Oregon 97201 —
Lehigh Valley Hospital Allentown Pennsylvania 18105 —
Heritage Valley Medical Group Beaver Pennsylvania 15009 —
Geisinger Medical Center Danville Pennsylvania 17822 —
University of Pennsylvania Philadelphia Pennsylvania 19104 —
Thomas Jefferson University Hospital Philadelphia Pennsylvania 19107 —
Allegheny Singer Research Institute Pittsburgh Pennsylvania 15212 —
UPMC Presbyterian Shadyside Pittsburgh Pennsylvania 15232 —
Rhode Island Hospital Providence Rhode Island 02903 —
South Carolina Heart Center Columbia South Carolina 29204 —
Metro Knoxville HMA Knoxville Tennessee 37920 —
Baptist Memorial Hospital Memphis Tennessee 38120 —
The University of Texas Southwestern Medical Center at Dallas Dallas Texas 75390 —
Houston Methodist Hospital Houston Texas 77030 —
UT Houston Memorial Houston Texas 77030 —
Scott & White Memorial Hospital Temple Texas 76508 —
Intermountain Health Services Salt Lake City Utah 84143 —
University of Virginia Charlottesville Virginia 22908 —
Swedish Health Services Seattle Washington 98122 —
Providence Health & Services - Washington Spokane Washington 99204 —
Charleston Area Medical Center Charleston West Virginia 25304 —
Marshfield Clinic Marshfield Wisconsin 54449 —
St. Luke's Medical Center Milwaukee Wisconsin 53215 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00004732, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 17, 2017 · Synced Oct 25, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00004732 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →