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Completed Phase 2Phase 3 Interventional

A Multicenter Trial of Rofecoxib and Naproxen in Alzheimer's Disease (NSAID Study)

ClinicalTrials.gov ID: NCT00004845

Public ClinicalTrials.gov record NCT00004845. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 8, 2026, 11:43 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter Trial of Rofecoxib and Naproxen in Alzheimer's Disease

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary specific aim of this clinical trial is to determine whether treatment with rofecoxib or naproxen for one year will slow the rate of decline of cognitive function in patients with Alzheimer's disease (AD) as measured by ADAScog.

Study identification

NCT ID
NCT00004845
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2, Phase 3
Enrollment
Not listed

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
55 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Not listed
Primary completion
Nov 30, 2001
Completion
Nov 30, 2001
Last update posted
Dec 10, 2009

Ends 2001

United States locations

U.S. sites
40
U.S. states
25
U.S. cities
37
Facility City State ZIP Site status
Barrow Neurological Group Phoenix Arizona 85013
University of Arizona, Tucson Tucson Arizona 85724-5023
University of California Irvine Institute for Brain Aging and Dementia Irvine California 92697-4285
University of California, San Diego La Jolla California 92037
University of Southern California Los Angeles California 90033-1039
University of California, Los Angeles Los Angeles California 90095-1769
University of California, Davis Martinez California 94553
Yale University, School of Medicine New Haven Connecticut 06520
Georgetown University Medical Center Washington D.C. District of Columbia 20007
Baumel-Eisner Neuromedical Institute, Boca Raton Boca Raton Florida 33486
Baumel-Eisner Ft Lauderdale Fort Lauderdale Florida 33321
Mayo Clinic Jacksonville Jacksonville Florida 32225
Wein Center Miami Beach Florida 33140
Baumel-Eisner Neuromedical Institute, MiamiBeach Miami Beach Florida 33154
University of South Florida Tampa Florida 33617
Premiere Research Institute West Palm Beach Florida 33407
Emory University Atlanta Georgia 30329
Rush Presbyterian St. Luke's Medical Center Chicago Illinois 60612
Indiana University Medical Center Indianapolis Indiana 46202-5266
Kansas University Kansas City Kansas 66160
University of Kentucky Lexington Kentucky 40536-0230
University of Michigan Ann Arbor Michigan 48109
University of Minnesota Minneapolis Minnesota 55455
Washington University St Louis Missouri 63108-2293
University of Nevada Las Vegas Nevada 89102
ClinSearch, Inc Summit New Jersey 07901
New York University Medical Center New York New York 10016
Columbia University New York New York 10032
University of Rochester Medical Center Rochester New York 14620
University Hospitals of Cleveland Cleveland Ohio 44120
Oregon Health Sciences University Portland Oregon 97201-3098
University of Pennsylvania Philadelphia Pennsylvania 19104
University of Pittsburgh Pittsburgh Pennsylvania 15213
Memorial Hospital of Rhode Island Providence Rhode Island 02906
Medical University of South Carolina North Charleston South Carolina 29406
Vanderbilt University Medical Center Nashville Tennessee 37212-8646
University of Texas, SW Medical Center Dallas Texas 75390-9070
Baylor College of Medicine Houston Texas 77030
Southwestern Vermont Medical Center Bennington Vermont 05201
University of Washington Seattle Washington 98108

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00004845, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 10, 2009 · Synced Sep 8, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00004845 live on ClinicalTrials.gov.

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