Safety and Effectiveness of Lamivudine When Given Once a Day Versus Twice a Day in Combination With Other Anti-HIV Drugs in HIV-Infected Adults Who Have Never Received Anti-HIV Drugs
Public ClinicalTrials.gov record NCT00004852. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II/III 48-Week, Randomized, Double-Blind, Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Lamivudine 300mg Once Daily Vs. Lamivudine 150mg BID in Combination With Zidovudine 300mg BID and Efavirenz 600mg Once Daily in Antiretroviral-Naive Adults With HIV-1 Infection
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to look at the safety and effectiveness of receiving lamivudine (3TC) once a day versus twice a day as part of an anti-HIV drug combination.
Study identification
- NCT ID
- NCT00004852
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- Not listed
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 1999 (Type not available)
- Primary completion
- Not listed
- Completion
- Not listed
- Last update posted
- Jun 24, 2005
Started 1999
United States locations
- U.S. sites
- 46
- U.S. states
- 19
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Phoenix Body Positive | Phoenix | Arizona | 85016 | — |
| Pacific Oaks Research | Beverly Hills | California | 90211 | — |
| AIDS Healthcare Foundation | Los Angeles | California | 900276069 | — |
| Tower ID Med Associates | Los Angeles | California | 90048 | — |
| Davies Med Ctr / c/o HIV Institute | San Francisco | California | 94114 | — |
| Kaiser Foundation Hospital | San Francisco | California | 94118 | — |
| Harbor - UCLA Med Ctr | Torrance | California | 90509 | — |
| Georgetown Univ Med Ctr | Washington D.C. | District of Columbia | 20007 | — |
| George Washington Univ Med Ctr | Washington D.C. | District of Columbia | 20037 | — |
| IDC Research Initiative | Altamonte Springs | Florida | 32701 | — |
| Bach and Godofsky | Bradenton | Florida | 34205 | — |
| TheraFirst Med Ctrs Inc | Fort Lauderdale | Florida | 33308 | — |
| North Broward Hosp District | Fort Lauderdale | Florida | 33316 | — |
| The Coleman Institute Inc | Fort Lauderdale | Florida | 33334 | — |
| The Coleman Institute Inc | Ft. Pierce | Florida | 34950 | — |
| Kaiser Permanente Infectious Diseases | Atlanta | Georgia | 30339 | — |
| AIDS Research Alliance - Chicago | Chicago | Illinois | 60657 | — |
| Infectious Disease of Indiana | Indianapolis | Indiana | 46218 | — |
| Univ of Kentucky Med Ctr | Lexington | Kentucky | 40536 | — |
| Tulane Univ School of Medicine | New Orleans | Louisiana | 70112 | — |
| Boston Med Ctr / Evans - 556 | Boston | Massachusetts | 021182393 | — |
| Antibiotic Research Associates | Kansas City | Missouri | 64132 | — |
| East Orange Veterans Administration Med Ctr | East Orange | New Jersey | 07018 | — |
| ID Care Inc | New Brunswick | New Jersey | 08901 | — |
| ID Care Inc | Princeton | New Jersey | 08540 | — |
| ID Care Inc | Randolph Township | New Jersey | 07869 | — |
| ID Care Inc | Somerville | New Jersey | 08876 | — |
| Albany Med College / Div of HIV Medicine | Albany | New York | 12208 | — |
| North Shore Univ Hosp / Div of Infectious Diseases | Manhasset | New York | 11030 | — |
| St Vincents Hosp / Clinical Research Program | New York | New York | 10011 | — |
| St Lukes / Roosevelt Hosp / HIV Center | New York | New York | 10019 | — |
| Ohio State Univ Hosp Clinic | Columbus | Ohio | 432101228 | — |
| Oklahoma State University / College of Osteopathic Medicine | Tulsa | Oklahoma | 74107 | — |
| Associates in Med and Mental Health | Tulsa | Oklahoma | 74114 | — |
| Miriam Hosp / Brown Univ | Providence | Rhode Island | 02906 | — |
| Methodist Healthcare | Memphis | Tennessee | 38104 | — |
| Univ of Tennessee | Memphis | Tennessee | 38163 | — |
| Vanderbilt Univ Med Ctr | Nashville | Tennessee | 37203 | — |
| Dr David Donnell | Dallas | Texas | 75219 | — |
| Nelson-Tebedo Community Clinic | Dallas | Texas | 75219 | — |
| Univ of Texas Med Branch | Galveston | Texas | 77555 | — |
| Montrose Clinic | Houston | Texas | 77006 | — |
| Baylor College of Medicine / Dept of Medicine | Houston | Texas | 770303498 | — |
| Univ of Texas / Med School at Houston | Houston | Texas | 77030 | — |
| Univ of Texas Health Sciences Ctr | San Antonio | Texas | 782847838 | — |
| Hampton Roads Med Specialists | Hampton | Virginia | 23666 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00004852, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 24, 2005 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00004852 live on ClinicalTrials.gov.