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Completed Phase 4 Interventional

Safety and Effectiveness of a Combination Anti-HIV Drug Treatment

ClinicalTrials.gov ID: NCT00005018

Public ClinicalTrials.gov record NCT00005018. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 25, 2026, 6:38 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase IV 48-Week, Randomized, Open-Label, Multicenter Trial of Abacavir (300mg BID)/Efavirenz (600mg QD)/Didanosine (400mg QD) +/- Hydroxyurea (500mg BID) in HIV-1 Infected Subjects Failing Initial Therapy With 3TC/ZDV (or d4T) +/- Protease Inhibitor(s)

Study identification

NCT ID
NCT00005018
Recruitment status
Completed
Study type
Interventional
Phase
Phase 4
Lead sponsor
Glaxo Wellcome
Industry
Enrollment
150 participants

Conditions and interventions

Conditions

Interventions

  • Hydroxyurea Drug
  • Abacavir sulfate Drug
  • Efavirenz Drug
  • Didanosine Drug

Drug

Eligibility (public fields only)

Age range
13 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 30, 1999
Primary completion
Not listed
Completion
Sep 30, 2000
Last update posted
Jun 23, 2005

1999 – 2000

United States locations

U.S. sites
23
U.S. states
13
U.S. cities
22
Facility City State ZIP Site status
East Bay AIDS Ctr Berkeley California 94705
Pacific Oaks Research Beverly Hills California 90211
Altamed Medical Health Services Los Angeles California 90022
St Lukes Medical Group San Diego California 92101
Pacific Horizons Med Group San Francisco California 94115
Gary Richmond MD Fort Lauderdale Florida 33316
Univ of Miami School of Medicine Miami Florida 331361013
Saint Josephs Comprehensive Research Institute Tampa Florida 33607
Northstar Med Clinic Chicago Illinois 60657
Univ of Kentucky Med Ctr Lexington Kentucky 40536
Boston Med Ctr / Evans - 556 Boston Massachusetts 021182393
CRI of New England Brookline Massachusetts 02445
Univ of Nebraska Medical Ctr Omaha Nebraska 681985400
Beth Israel Med Ctr New York New York 10003
Saint Luke's - Roosevelt Hosp Ctr New York New York 10019
Univ of North Carolina / Infectious Disease Division Chapel Hill North Carolina 27599
Univ of NC Infectious Diseases Wilmington North Carolina 28402
Anderson Clinical Research Inc Reading Pennsylvania 19604
Miriam Hosp Providence Rhode Island 02906
Burnside Clinic Columbia South Carolina 29206
Univ of Texas Med Branch Galveston Texas 77555
Univ of Texas / Thomas Street Clinic Houston Texas 77030
Hampton Roads Med Specialists Hampton Virginia 23666

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00005018, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 23, 2005 · Synced Jun 25, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00005018 live on ClinicalTrials.gov.

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