Safety and Effectiveness of a Combination Anti-HIV Drug Treatment
Public ClinicalTrials.gov record NCT00005018. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Phase IV 48-Week, Randomized, Open-Label, Multicenter Trial of Abacavir (300mg BID)/Efavirenz (600mg QD)/Didanosine (400mg QD) +/- Hydroxyurea (500mg BID) in HIV-1 Infected Subjects Failing Initial Therapy With 3TC/ZDV (or d4T) +/- Protease Inhibitor(s)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to see if it is safe and effective to give HIV-positive patients a combination of anti-HIV drugs (abacavir \[ABC\] plus efavirenz \[EFV\] plus didanosine \[ddI\]) with and without hydroxyurea (HU).
Study identification
- NCT ID
- NCT00005018
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 150 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 13 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 1999 (Type not available)
- Primary completion
- Not listed
- Completion
- Oct 2000 (Type not available)
- Last update posted
- Jun 24, 2005
1999 – 2000
United States locations
- U.S. sites
- 23
- U.S. states
- 13
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| East Bay AIDS Ctr | Berkeley | California | 94705 | — |
| Pacific Oaks Research | Beverly Hills | California | 90211 | — |
| Altamed Medical Health Services | Los Angeles | California | 90022 | — |
| St Lukes Medical Group | San Diego | California | 92101 | — |
| Pacific Horizons Med Group | San Francisco | California | 94115 | — |
| Gary Richmond MD | Fort Lauderdale | Florida | 33316 | — |
| Univ of Miami School of Medicine | Miami | Florida | 331361013 | — |
| Saint Josephs Comprehensive Research Institute | Tampa | Florida | 33607 | — |
| Northstar Med Clinic | Chicago | Illinois | 60657 | — |
| Univ of Kentucky Med Ctr | Lexington | Kentucky | 40536 | — |
| Boston Med Ctr / Evans - 556 | Boston | Massachusetts | 021182393 | — |
| CRI of New England | Brookline | Massachusetts | 02445 | — |
| Univ of Nebraska Medical Ctr | Omaha | Nebraska | 681985400 | — |
| Beth Israel Med Ctr | New York | New York | 10003 | — |
| Saint Luke's - Roosevelt Hosp Ctr | New York | New York | 10019 | — |
| Univ of North Carolina / Infectious Disease Division | Chapel Hill | North Carolina | 27599 | — |
| Univ of NC Infectious Diseases | Wilmington | North Carolina | 28402 | — |
| Anderson Clinical Research Inc | Reading | Pennsylvania | 19604 | — |
| Miriam Hosp | Providence | Rhode Island | 02906 | — |
| Burnside Clinic | Columbia | South Carolina | 29206 | — |
| Univ of Texas Med Branch | Galveston | Texas | 77555 | — |
| Univ of Texas / Thomas Street Clinic | Houston | Texas | 77030 | — |
| Hampton Roads Med Specialists | Hampton | Virginia | 23666 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00005018, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 24, 2005 · Synced Nov 7, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00005018 live on ClinicalTrials.gov.