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Completed Phase 1Phase 2 Interventional

Tipifarnib in Treating Patients With Recurrent or Progressive Malignant Glioma

ClinicalTrials.gov ID: NCT00005859

Public ClinicalTrials.gov record NCT00005859. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 1, 2026, 3:05 PM EST

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase I/II Trial of R115777 in Patients With Recurrent Malignant Glioma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Tipifarnib may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth. PURPOSE: Phase II trial to study the effectiveness of tipifarnib in treating patients who have recurrent or progressive malignant glioma.

Study identification

NCT ID
NCT00005859
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Enrollment
136 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 120 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 16, 2000 (Actual)
Primary completion
Jul 1, 2005 (Actual)
Completion
Aug 1, 2006 (Actual)
Last update posted
Jun 26, 2018

2000 – 2006

United States locations

U.S. sites
11
U.S. states
8
U.S. cities
11
Facility City State ZIP Site status
Jonsson Comprehensive Cancer Center, UCLA Los Angeles California 90095 —
UCSF Comprehensive Cancer Center San Francisco California 94115 —
Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support Bethesda Maryland 20892-1182 —
Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute Boston Massachusetts 02115 —
University of Michigan Comprehensive Cancer Center Ann Arbor Michigan 48109-0942 —
Memorial Sloan-Kettering Cancer Center New York New York 10021 —
Hillman Cancer Center at University of Pittsburgh Cancer Institute Pittsburgh Pennsylvania 15232 —
Simmons Cancer Center at University of Texas Southwestern Medical Center - Dallas Dallas Texas 75390-9154 —
University of Texas - MD Anderson Cancer Center Houston Texas 77030-4009 —
University of Texas Health Science Center at San Antonio San Antonio Texas 78284-6220 —
University of Wisconsin Comprehensive Cancer Center Madison Wisconsin 53792 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00005859, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 26, 2018 · Synced Nov 1, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00005859 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →