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Completed Phase 3 Interventional

Radiation Therapy With or Without RSR13 in Treating Patients With Brain Metastases

ClinicalTrials.gov ID: NCT00005887

Public ClinicalTrials.gov record NCT00005887. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 6, 2026, 11:49 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Randomized, Open-Label, Comparative Study of Standard Whole Brain Radiation Therapy With or Without RSR13 in Patients With Brain Metastases

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs such as RSR13 may make tumor cells more sensitive to radiation therapy. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy to the brain with or without RSR13 in treating patients who have brain metastases.

Study identification

NCT ID
NCT00005887
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Spectrum Pharmaceuticals, Inc
Industry
Enrollment
Not listed

Conditions and interventions

Interventions

Drug · Radiation

Eligibility (public fields only)

Age range
18 Years to 120 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 31, 2000
Primary completion
Dec 31, 2002
Completion
Dec 31, 2002
Last update posted
Aug 22, 2021

2000 – 2003

United States locations

U.S. sites
35
U.S. states
18
U.S. cities
31
Facility City State ZIP Site status
St. Joseph's Hospital and Medical Center Phoenix Arizona 85001-2071
Arizona Cancer Center Tucson Arizona 85724
Alta Bates Comprehensive Cancer Center Berkeley California 94704
California Cancer Care, Inc. Greenbrae California 94904
Scripps Green Hospital & Scripps Clinic La Jolla California 92037
Tower Hematology Oncology Medical Group Los Angeles California 90048
University of Colorado Cancer Center Denver Colorado 80010
Comprehensive Cancer Care Specialists of Boca Raton Boca Raton Florida 33428
Citrus Memorial Hospital Inverness Florida 34452
Decatur Memorial Hospital Cancer Care Institute Decatur Illinois 62526
Ochsner Clinic New Orleans Louisiana 70121
Harbor Hospital Center Baltimore Maryland 21225
St. Agnes Healthcare Baltimore Maryland 21229
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore Maryland 21231-2410
Lahey Clinic - Burlington Burlington Massachusetts 01805
University of Massachusetts Memorial Medical Center Worcester Massachusetts 01655
Cooper Hospital/University Medical Center Camden New Jersey 08103
Monmouth Medical Center Long Branch New Jersey 07740-6395
East Coast Radiation Oncology Toms River New Jersey 08755
Millard Fillmore Hospital Buffalo New York 14209
State University of New York - Upstate Medical University Syracuse New York 13210
Comprehensive Cancer Center at Wake Forest University Winston-Salem North Carolina 27157-1082
Bismarck Cancer Center Bismarck North Dakota 58501-4445
Akron General Medical Center Akron Ohio 44302
Akron City Hospital Akron Ohio 44309
Cleveland Clinic Taussig Cancer Center Cleveland Ohio 44195
Kimmel Cancer Center of Thomas Jefferson University - Philadelphia Philadelphia Pennsylvania 19107-5541
Memphis Regional Brain Tumor Center Memphis Tennessee 38104
Boston Baskin Cancer Group, University Tennessee Oncology/Hematology Group Memphis Tennessee 38119
U.S. Oncology Research Inc. Dallas Texas 75246
University of Texas - MD Anderson Cancer Center Houston Texas 77030-4009
University of Texas Health Science Center at San Antonio San Antonio Texas 78284-7811
Center for Radiation Oncology Danville Virginia 24541
Massey Cancer Center Richmond Virginia 23298-0037
Veterans Affairs Medical Center - Milwaukee (Zablocki) Milwaukee Wisconsin 53295

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 38 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00005887, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 22, 2021 · Synced Sep 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00005887 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →