Combination Chemotherapy Plus Trastuzumab in Treating Patients With Advanced, Recurrent, or Metastatic Colorectal Cancer
Public ClinicalTrials.gov record NCT00006015. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase II Study Evaluating the Combination of 5-Fluorouracil, Leucovorin, Oxaliplatin, and Herceptin in the Treatment of Patients With Metastatic Colorectal Cancer Who Have Progressed After 5-FU and/or Irinotecan-Containing Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Monoclonal antibodies such as trastuzumab can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. PURPOSE: This phase II trial is studying combination chemotherapy plus trastuzumab to see how well it works in treating patients with advanced, recurrent, or metastatic colorectal cancer.
Study identification
- NCT ID
- NCT00006015
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 26 participants
Conditions and interventions
Conditions
Interventions
- trastuzumab Biological
- fluorouracil Drug
- leucovorin calcium Drug
- oxaliplatin Drug
Biological · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2000 (Type not available)
- Primary completion
- Dec 2002 (Actual)
- Completion
- Feb 2003 (Actual)
- Last update posted
- May 3, 2013
2000 – 2003
United States locations
- U.S. sites
- 47
- U.S. states
- 22
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Veterans Affairs Medical Center - Birmingham | Birmingham | Alabama | 35233-1996 | — |
| University of California San Diego Cancer Center | La Jolla | California | 92093-0658 | — |
| Veterans Affairs Medical Center - San Francisco | San Francisco | California | 94121 | — |
| UCSF Cancer Center and Cancer Research Institute | San Francisco | California | 94143-0128 | — |
| CCOP - Christiana Care Health Services | Wilmington | Delaware | 19899 | — |
| Lombardi Cancer Center | Washington D.C. | District of Columbia | 20007 | — |
| Walter Reed Army Medical Center | Washington D.C. | District of Columbia | 20307-5000 | — |
| CCOP - Mount Sinai Medical Center | Miami Beach | Florida | 33140 | — |
| Veterans Affairs Medical Center - Chicago (Westside Hospital) | Chicago | Illinois | 60612 | — |
| University of Chicago Cancer Research Center | Chicago | Illinois | 60637-1470 | — |
| Hematology Oncology Associates of the Quad Cities | Bettendorf | Iowa | 52722 | — |
| Holden Comprehensive Cancer Center | Iowa City | Iowa | 52242-1009 | — |
| Veterans Affairs Medical Center - Togus | Togus | Maine | 04330 | — |
| Marlene and Stewart Greenebaum Cancer Center, University of Maryland | Baltimore | Maryland | 21201 | — |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| University of Massachusetts Memorial Medical Center - University Campus | Worcester | Massachusetts | 01655 | — |
| Veterans Affairs Medical Center - Minneapolis | Minneapolis | Minnesota | 55417 | — |
| University of Minnesota Cancer Center | Minneapolis | Minnesota | 55455 | — |
| Veterans Affairs Medical Center - Columbia (Truman Memorial) | Columbia | Missouri | 65201 | — |
| Ellis Fischel Cancer Center - Columbia | Columbia | Missouri | 65203 | — |
| Barnes-Jewish Hospital | St Louis | Missouri | 63110 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198-7680 | — |
| CCOP - Southern Nevada Cancer Research Foundation | Las Vegas | Nevada | 89106 | — |
| Norris Cotton Cancer Center | Lebanon | New Hampshire | 03756-0002 | — |
| Veterans Affairs Medical Center - Buffalo | Buffalo | New York | 14215 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263-0001 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10021 | — |
| New York Presbyterian Hospital - Cornell Campus | New York | New York | 10021 | — |
| Mount Sinai Medical Center, NY | New York | New York | 10029 | — |
| State University of New York - Upstate Medical University | Syracuse | New York | 13210 | — |
| Veterans Affairs Medical Center - Syracuse | Syracuse | New York | 13210 | — |
| CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C. | Syracuse | New York | 13217 | — |
| Lineberger Comprehensive Cancer Center, UNC | Chapel Hill | North Carolina | 27599-7295 | — |
| Veterans Affairs Medical Center - Durham | Durham | North Carolina | 27705 | — |
| Duke Comprehensive Cancer Center | Durham | North Carolina | 27710 | — |
| CCOP - Southeast Cancer Control Consortium | Winston-Salem | North Carolina | 27104-4241 | — |
| Comprehensive Cancer Center at Wake Forest University | Winston-Salem | North Carolina | 27157-1082 | — |
| Arthur G. James Cancer Hospital - Ohio State University | Columbus | Ohio | 43210-1240 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| University of Tennessee Cancer Institute | Memphis | Tennessee | 38103 | — |
| Veterans Affairs Medical Center - Memphis | Memphis | Tennessee | 38104 | — |
| Green Mountain Oncology Group | Bennington | Vermont | 05201 | — |
| Vermont Cancer Center | Burlington | Vermont | 05401-3498 | — |
| Veterans Affairs Medical Center - White River Junction | White River Junction | Vermont | 05009 | — |
| Veterans Affairs Medical Center - Richmond | Richmond | Virginia | 23249 | — |
| MBCCOP - Massey Cancer Center | Richmond | Virginia | 23298-0037 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00006015, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 3, 2013 · Synced Sep 30, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00006015 live on ClinicalTrials.gov.