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Terminated Phase 3 Interventional

The Safety and Efficacy of an Investigational Drug in Delaying the Progression of Alzheimer's Disease

ClinicalTrials.gov ID: NCT00006187

Public ClinicalTrials.gov record NCT00006187. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 18, 2026, 4:44 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a 15-month study with two phases. During the first 12-month phase of this study, patients will be randomly assigned to receive either active study drug or placebo (approximately half of all patients will be on active study drug, the other half on placebo). The second phase is a 3-month randomized withdrawal period. For this phase approximately 10% of the patients will remain on the active drug.

Study identification

NCT ID
NCT00006187
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Enrollment
Not listed

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Not listed
Primary completion
May 31, 2005
Completion
May 31, 2005
Last update posted
Dec 10, 2009

Ends 2005

United States locations

U.S. sites
34
U.S. states
16
U.S. cities
32
Facility City State ZIP Site status
Pivotal Research Centers Peoria Arizona 85381
California Clinical Trials Beverly Hills California 90211
Pharmacology Research Institute Los Alamitos California 90720
Pharmacology Research Institute Newport Beach California 92660
Daniel Grosz MD Northridge California 91324
Pharmacology Research Institute Riverside California 92506
Pacific Research Network San Diego California 92103
San Francisco Headache Clinic San Francisco California 94109
Yale University, Alzheimer's Disease ResearchUnit New Haven Connecticut 06520-8037
New England Center for Headache Stamford Connecticut 06902
Baumel-Eisner Neuromedical Institute Boca Raton Florida 33486
Baumel-Eisner Neuromedical Institute Fort Lauderdale Florida 33321
ICSL Clinical Studies Fort Myers Florida 33907
ICSL Clinical Studies Melbourne Florida 32935
ICSL Clinical Studies Sarasota Florida 34232
ICSL Clinical Studies St. Petersburg Florida 33702
Meridien Research St. Petersburg Florida 33710
Premiere Research Institute West Palm Beach Florida 33407
Palm Beach Neurological Center West Palm Beach Florida 33410
Chicago Center for Clinical Research Chicago Illinois 60610
ICSL Clinical Studies South Yarmouth Massachusetts 02664
Las Vegas Center for Clinical Research Las Vegas Nevada 89146
Nathan Klein Institute Orangeburg New York 10962
University of Rochester Rochester New York 14620
Piedmont Medical Research Associates Winston-Salem North Carolina 27103
Pahl Brain Associates, P.C. Oklahoma City Oklahoma 73118
Clinical Pharmaceutical Trials Tulsa Oklahoma 74104-5428
Pacific NW Clinical Research Center Portland Oregon 97223
Institute for Advanced Clinical Research Elkins Park Pennsylvania 19027
ICSL Clinical Studies Philadelphia Pennsylvania 19106
ICSL Clinical Studies East Providence Rhode Island 02915
Pharmacology Research Clinic Salt Lake City Utah 84107
Seattle Clinical Research Center Seattle Washington 98104
Froedtert Lutheran Memorial Hospital Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00006187, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 10, 2009 · Synced Sep 18, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00006187 live on ClinicalTrials.gov.

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