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Completed Phase 2Phase 3 Interventional

Paclitaxel + Carboplatin With/ut BMS-275291 in Advanced or Metastatic Non-small Cell Lung Cancer

ClinicalTrials.gov ID: NCT00006229

Public ClinicalTrials.gov record NCT00006229. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 8:56 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II/III Double Blind Randomized Trial of BMS-275291 vs. Placebo in Patients Receiving Paclitaxel/Carboplatin Chemotherapy for the Treatment of Advanced or Metastatic Non-small Cell Lung Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether paclitaxel and carboplatin are more effective with or without BMS-275291 for non-small cell lung cancer. PURPOSE: Randomized phase II/III trial to compare the effectiveness of paclitaxel and carboplatin with or without BMS-275291 in treating patients who have advanced or metastatic non-small cell lung cancer.

Study identification

NCT ID
NCT00006229
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
NCIC Clinical Trials Group
Network
Enrollment
774 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 120 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 3, 2000
Primary completion
Dec 9, 2003
Completion
Feb 9, 2009
Last update posted
Apr 5, 2020

2000 – 2009

United States locations

U.S. sites
18
U.S. states
11
U.S. cities
15
Facility City State ZIP Site status
University of Alabama at Birmingham Comprehensive Cancer Center Birmingham Alabama 35294-3300
University of Arkansas for Medical Sciences Little Rock Arkansas 72205
Scripps Clinic La Jolla California 92037
Central Georgia Hematology Oncology, P.C. Macon Georgia 31201
Queen's Medical Center Honolulu Hawaii 96813
Carle Cancer Center Urbana Illinois 61801
Lahey Clinic - Burlington Burlington Massachusetts 01805
Creighton University Cancer Center Omaha Nebraska 68131-2197
Duke University Medical Center Durham North Carolina 27710
University of Oklahoma Health Sciences Center Oklahoma City Oklahoma 73190
Erlanger Health Systems Chattanooga Tennessee 37403
Memorial Hospital Cancer Center - Chattanooga Chattanooga Tennessee 37404
Williamson Medical Center Franklin Tennessee 37068-1600
Jackson-Madison County General Hospital Jackson Tennessee 38301
Baptist Regional Cancer Center - Knoxville Knoxville Tennessee 37901
Saint Thomas Hospital Nashville Tennessee 37205
Meharry Medical College Nashville Tennessee 37208-3599
Division of Medical Oncology - Vanderbilt Nashville Tennessee 37232-5536

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 51 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00006229, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 5, 2020 · Synced Sep 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00006229 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →