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Completed Phase 2 Interventional

Dexamethasone Followed by Denileukin Diftitox in Treating Patients With Persistent or Recurrent T-Cell Lymphoma

ClinicalTrials.gov ID: NCT00006345

Public ClinicalTrials.gov record NCT00006345. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 8:51 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Evaluation of Corticosteroid Pretreatment in Cutaneous T-Cell Lymphoma Patients Receiving Ontak (Denileukin Difitox)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Denileukin diftitox may be able to deliver cancer-killing substances directly to T-cell lymphoma cells. Dexamethasone may decrease the side effects of denileukin diftitox. PURPOSE: Phase II trial to study the effectiveness of dexamethasone in preventing side effects following treatment with denileukin diftitox in treating patients who have persistent or recurrent T-cell lymphoma.

Study identification

NCT ID
NCT00006345
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Ligand Pharmaceuticals
Industry
Enrollment
Not listed

Conditions and interventions

Interventions

Biological · Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 31, 1999
Primary completion
Not listed
Completion
Feb 29, 2004
Last update posted
May 29, 2013

1999 – 2004

United States locations

U.S. sites
11
U.S. states
9
U.S. cities
11
Facility City State ZIP Site status
Veterans Affairs Medical Center - Miami Miami Florida 33125
Rush Cancer Institute Chicago Illinois 60612
Tulane University School of Medicine New Orleans Louisiana 70112
Beth Israel Deaconess Medical Center Boston Massachusetts 02215
Washington University School of Medicine St Louis Missouri 63110
Comprehensive Cancer Center at Wake Forest University Winston-Salem North Carolina 27157-1082
Hahnemann University Hospital Philadelphia Pennsylvania 19102-1192
University of Pittsburgh Cancer Institute Pittsburgh Pennsylvania 15213-3489
Vanderbilt-Ingram Cancer Center Nashville Tennessee 37232-6838
Arlington Cancer Center Arlington Texas 76012
University of Texas - MD Anderson Cancer Center Houston Texas 77030-4009

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00006345, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 29, 2013 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00006345 live on ClinicalTrials.gov.

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