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Completed Phase 2 Interventional

Dexamethasone Followed by Denileukin Diftitox in Treating Patients With Persistent or Recurrent T-Cell Lymphoma

ClinicalTrials.gov ID: NCT00006345

Public ClinicalTrials.gov record NCT00006345. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 20, 2026, 1:49 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Evaluation of Corticosteroid Pretreatment in Cutaneous T-Cell Lymphoma Patients Receiving Ontak (Denileukin Difitox)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Denileukin diftitox may be able to deliver cancer-killing substances directly to T-cell lymphoma cells. Dexamethasone may decrease the side effects of denileukin diftitox. PURPOSE: Phase II trial to study the effectiveness of dexamethasone in preventing side effects following treatment with denileukin diftitox in treating patients who have persistent or recurrent T-cell lymphoma.

Study identification

NCT ID
NCT00006345
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Ligand Pharmaceuticals
Industry
Enrollment
Not listed

Conditions and interventions

Interventions

Biological · Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 1999 (Type not available)
Primary completion
Not listed
Completion
Mar 2004 (Actual)
Last update posted
May 30, 2013

1999 – 2004

United States locations

U.S. sites
11
U.S. states
9
U.S. cities
11
Facility City State ZIP Site status
Veterans Affairs Medical Center - Miami Miami Florida 33125 —
Rush Cancer Institute Chicago Illinois 60612 —
Tulane University School of Medicine New Orleans Louisiana 70112 —
Beth Israel Deaconess Medical Center Boston Massachusetts 02215 —
Washington University School of Medicine St Louis Missouri 63110 —
Comprehensive Cancer Center at Wake Forest University Winston-Salem North Carolina 27157-1082 —
Hahnemann University Hospital Philadelphia Pennsylvania 19102-1192 —
University of Pittsburgh Cancer Institute Pittsburgh Pennsylvania 15213-3489 —
Vanderbilt-Ingram Cancer Center Nashville Tennessee 37232-6838 —
Arlington Cancer Center Arlington Texas 76012 —
University of Texas - MD Anderson Cancer Center Houston Texas 77030-4009 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00006345, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 30, 2013 · Synced Oct 20, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00006345 live on ClinicalTrials.gov.

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