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Completed Phase 1 Interventional

Ecteinascidin 743 in Treating Children With Refractory Solid Tumors

ClinicalTrials.gov ID: NCT00006463

Public ClinicalTrials.gov record NCT00006463. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 2:54 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase I Study of ET-743 in Pediatric Refractory Solid Tumors

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Ecteinascidin 743 may be an effective treatment for solid tumors. PURPOSE: Phase I trial to study the effectiveness of ecteinascidin 743 in treating children who have refractory solid tumors.

Study identification

NCT ID
NCT00006463
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Children's Oncology Group
Network
Enrollment
13 participants

Conditions and interventions

Eligibility (public fields only)

Age range
1 Year to 17 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 2000 (Type not available)
Primary completion
Jan 2005 (Actual)
Completion
Sep 2005 (Actual)
Last update posted
Feb 21, 2014

2000 – 2005

United States locations

U.S. sites
42
U.S. states
24
U.S. cities
37
Facility City State ZIP Site status
University of Arkansas for Medical Sciences Little Rock Arkansas 72205 —
University of California San Diego Cancer Center La Jolla California 92093-0658 —
Children's Hospital Los Angeles Los Angeles California 90027-0700 —
Jonsson Comprehensive Cancer Center, UCLA Los Angeles California 90095-1781 —
Beckman Research Institute, City of Hope Los Angeles California 91010 —
Children's Hospital of Orange County Orange California 92868 —
Lucile Packard Children's Hospital at Stanford Palo Alto California 94304 —
UCSF Cancer Center and Cancer Research Institute San Francisco California 94115-0128 —
Children's National Medical Center Washington D.C. District of Columbia 20010-2970 —
Shands Hospital and Clinics, University of Florida Gainesville Florida 32610-100277 —
Emory University Hospital - Atlanta Atlanta Georgia 30322 —
Children's Memorial Hospital, Chicago Chicago Illinois 60614 —
Indiana University Cancer Center Indianapolis Indiana 46202-5265 —
Johns Hopkins Oncology Center Baltimore Maryland 21231 —
Boston Floating Hospital Infants and Children Boston Massachusetts 02111 —
Dana-Farber Cancer Institute Boston Massachusetts 02115 —
Mott Children's Hospital Ann Arbor Michigan 48109 —
Children's Hospital of Michigan Detroit Michigan 48201 —
Mayo Clinic Cancer Center Rochester Minnesota 55905 —
University of Mississippi Medical Center Jackson Mississippi 39216-4505 —
Children's Mercy Hospital Kansas City Missouri 64108 —
Cardinal Glennon Children's Hospital St Louis Missouri 63104 —
Hackensack University Medical Center Hackensack New Jersey 07601 —
Roswell Park Cancer Institute Buffalo New York 14263-0001 —
Memorial Sloan-Kettering Cancer Center New York New York 10021 —
Columbia Presbyterian Hospital New York New York 10032 —
State University of New York - Upstate Medical University Syracuse New York 13210 —
Duke Comprehensive Cancer Center Durham North Carolina 27710 —
Children's Hospital Medical Center - Cincinnati Cincinnati Ohio 45229-3039 —
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104 —
Children's Hospital of Pittsburgh Pittsburgh Pennsylvania 15213 —
Medical University of South Carolina Charleston South Carolina 29425-0721 —
Saint Jude Children's Research Hospital Memphis Tennessee 38105-2794 —
Vanderbilt Cancer Center Nashville Tennessee 37232-6838 —
Cook Children's Medical Center - Fort Worth Fort Worth Texas 76104 —
University of Texas - MD Anderson Cancer Center Houston Texas 77030-4009 —
Baylor College of Medicine Houston Texas 77030 —
University of Texas Health Science Center at San Antonio San Antonio Texas 78284-7811 —
Huntsman Cancer Institute Salt Lake City Utah 84132 —
Children's Hospital and Regional Medical Center - Seattle Seattle Washington 98105 —
University of Wisconsin Hospital and Clinics Madison Wisconsin 53792-0001 —
Midwest Children's Cancer Center Milwaukee Wisconsin 53226 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00006463, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 21, 2014 · Synced Oct 19, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00006463 live on ClinicalTrials.gov.

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