ClinicalTrials.gov record
Comparison of Combination Chemotherapy Regimens in Treating Patients With Ewing's Sarcoma or Neuroectodermal Tumor
ClinicalTrials.gov ID: NCT00006734
Public ClinicalTrials.gov record NCT00006734. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Trial of Chemotherapy Intensification Through Compression in Ewing's Sarcoma and Related Tumors
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known which chemotherapy regimen combined with radiation therapy and/or surgery is more effective in treating Ewing's sarcoma or primitive neuroectodermal tumor. PURPOSE: Randomized phase III trial to compare the effectiveness of different chemotherapy regimens combined with radiation therapy and/or surgery in treating patients who have Ewing's sarcoma or primitive neuroectodermal tumor.
Study identification
- NCT ID
- NCT00006734
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 587 participants
Conditions and interventions
Conditions
Interventions
- filgrastim Biological
- cyclophosphamide Drug
- doxorubicin hydrochloride Drug
- etoposide Drug
- ifosfamide Drug
- vincristine sulfate Drug
- adjuvant therapy Procedure
- conventional surgery Procedure
- neoadjuvant therapy Procedure
- brachytherapy Radiation
- radiation therapy Radiation
Biological · Drug · Procedure + 1 more
Eligibility (public fields only)
- Age range
- 0 Years to 50 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2001 (Type not available)
- Primary completion
- Aug 2006 (Actual)
- Completion
- Jun 30, 2023 (Actual)
- Last update posted
- Aug 3, 2023
2001 – 2023
United States locations
- U.S. sites
- 212
- U.S. states
- 48
- U.S. cities
- 158
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Comprehensive Cancer Center at University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| University of South Alabama Cancer Research Institute | Mobile | Alabama | 36604 | — |
| Phoenix Children's Hospital | Phoenix | Arizona | 85016 | — |
| Arizona Cancer Center at University of Arizona Health Sciences Center | Tucson | Arizona | 85724 | — |
| Arkansas Cancer Research Center at University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Southern California Permanente Medical Group | Downey | California | 90242 | — |
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010-3000 | — |
| Rebecca and John Moores UCSD Cancer Center | La Jolla | California | 92093-0658 | — |
| Loma Linda University Cancer Institute at Loma Linda University Medical Center | Loma Linda | California | 92354 | — |
| Jonathan Jaques Children's Cancer Center at Miller Children's Hospital | Long Beach | California | 90801-1428 | — |
| Children's Hospital Los Angeles | Los Angeles | California | 90027-0700 | — |
| Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| Jonsson Comprehensive Cancer Center at UCLA | Los Angeles | California | 90095-1781 | — |
| Children's Hospital Central California | Madera | California | 93638-8762 | — |
| Children's Hospital and Research Center at Oakland | Oakland | California | 94609-1809 | — |
| Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center | Orange | California | 92868 | — |
| Children's Hospital of Orange County | Orange | California | 92868 | — |
| Lucile Packard Children's Hospital at Stanford University Medical Center | Palo Alto | California | 94304 | — |
| Sutter Cancer Center | Sacramento | California | 95816 | — |
| University of California Davis Cancer Center | Sacramento | California | 95817 | — |
| Kaiser Permanente Medical Center - Sacramento | Sacramento | California | 95825 | — |
| Kaiser Permanente Medical Center/Kaiser Foundation Hospital - San Diego | San Diego | California | 92120 | — |
| Children's Hospital and Health Center - San Diego | San Diego | California | 92123-4282 | — |
| UCSF Comprehensive Cancer Center | San Francisco | California | 94143 | — |
| Santa Barbara Cottage Hospital | Santa Barbara | California | 93102 | — |
| Kaiser Permanente Medical Center - Santa Clara | Santa Clara | California | 95051-5386 | — |
| General Robert Huyser Cancer Center at David Grant Medical Center | Travis Air Force Base | California | 94535 | — |
| Children's Hospital Cancer Center | Denver | Colorado | 80218 | — |
| Presbyterian - St. Luke's Medical Center | Denver | Colorado | 80218 | — |
| Carole and Ray Neag Comprehensive Cancer Center at the University of Connecticut Health Center | Farmington | Connecticut | 06360-7106 | — |
| Yale Comprehensive Cancer Center | New Haven | Connecticut | 06520-8064 | — |
| Alfred I. duPont Hospital for Children | Wilmington | Delaware | 19899 | — |
| Lombardi Cancer Center at Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007 | — |
| Children's National Medical Center | Washington D.C. | District of Columbia | 20010-2970 | — |
| Broward General Medical Center | Fort Lauderdale | Florida | 33316 | — |
| Children's Hospital of Southwest Florida | Fort Myers | Florida | 33908 | — |
| University of Florida Shands Cancer Center | Gainesville | Florida | 32610-0296 | — |
| Joe DiMaggio Children's Hospital at Memorial | Hollywood | Florida | 33021 | — |
| Nemours Children's Clinic | Jacksonville | Florida | 32207 | — |
| Jackson Memorial Hospital | Miami | Florida | 33136 | — |
| Miami Children's Hospital | Miami | Florida | 33155 | — |
| Baptist-South Miami Regional Cancer Program | Miami | Florida | 33176-2197 | — |
| Florida Hospital Cancer Institute | Orlando | Florida | 32804 | — |
| Nemours Children's Clinic-Orlando | Orlando | Florida | 32806 | — |
| Sacred Heart Children's Hospital | Pensacola | Florida | 32504 | — |
| All Children's Hospital | St. Petersburg | Florida | 33701 | — |
| St. Joseph's Children's Hospital of Tampa | Tampa | Florida | 33677-4227 | — |
| Kaplan Cancer Center at St. Mary's Medical Center | West Palm Beach | Florida | 33407 | — |
| AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Scottish Rite Campus | Atlanta | Georgia | 30342 | — |
| MBCCOP-Medical College of Georgia Cancer Center | Augusta | Georgia | 30912-4000 | — |
| Medical Center of Central Georgia | Macon | Georgia | 31201 | — |
| Curtis & Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center | Savannah | Georgia | 31405 | — |
| Cancer Research Center of Hawaii | Honolulu | Hawaii | 96813 | — |
| Tripler Army Medical Center | Honolulu | Hawaii | 96859-5000 | — |
| St. Luke's Mountain States Tumor Institute - Boise | Boise | Idaho | 83712 | — |
| University of Chicago Cancer Research Center | Chicago | Illinois | 60601 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| University of Illinois Medical Center | Chicago | Illinois | 60612 | — |
| Children's Memorial Hospital - Chicago | Chicago | Illinois | 60614 | — |
| Advocate Hope Children's Hospital | Oak Lawn | Illinois | 60453 | — |
| Lutheran General Cancer Care Center | Park Ridge | Illinois | 60068-1174 | — |
| Saint Jude Midwest Affiliate | Peoria | Illinois | 61637 | — |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62794-9658 | — |
| Riley Children Cancer Center at Riley Hospital for Children | Indianapolis | Indiana | 46202-5225 | — |
| St. Vincent Hospitals and Health Care Centers | Indianapolis | Indiana | 46260 | — |
| Blank Children's Hospital | Des Moines | Iowa | 50308 | — |
| Holden Comprehensive Cancer Center at University of Iowa | Iowa City | Iowa | 52242-1009 | — |
| Wesley Medical Center | Wichita | Kansas | 67214 | — |
| Markey Cancer Center at University of Kentucky Chandler Medical Center | Lexington | Kentucky | 40536-0284 | — |
| Kosair Children's Hospital | Louisville | Kentucky | 40202-3830 | — |
| MBCCOP - LSU Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Tulane Cancer Center at Tulane University Hospital and Clinic | New Orleans | Louisiana | 70112 | — |
| Children's Hospital of New Orleans | New Orleans | Louisiana | 70118 | — |
| Ochsner Cancer Institute at Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| Pediatric Specialty Clinic at Eastern Maine Medical Center | Bangor | Maine | 04401 | — |
| Maine Children's Cancer Program | Scarborough | Maine | 04074-9308 | — |
| Greenebaum Cancer Center at University of Maryland Medical Center | Baltimore | Maryland | 21201-1595 | — |
| Alvin and Lois Lapidus Cancer Institute at Sinai Hospital | Baltimore | Maryland | 21215 | — |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Baltimore | Maryland | 21231-7223 | — |
| Walter Reed Army Medical Center | Silver Spring | Maryland | 20910 | — |
| Floating Hospital for Children | Boston | Massachusetts | 02111 | — |
| Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| Baystate Regional Cancer Program at D'Amour Center for Cancer Care | Springfield | Massachusetts | 01107 | — |
| UMASS Memorial Cancer Center - University Campus | Worcester | Massachusetts | 01655 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109-0914 | — |
| Children's Hospital of Michigan | Detroit | Michigan | 48201 | — |
| Van Elslander Cancer Center at St. John Hospital and Medical Center | Detroit | Michigan | 48236 | — |
| Hurley Medical Center | Flint | Michigan | 48503 | — |
| DeVos Children's Hospital | Grand Rapids | Michigan | 49503 | — |
| Bronson Methodist Hospital | Kalamazoo | Michigan | 49007-5364 | — |
| Breslin Cancer Center at Ingham Regional Medical Center | Lansing | Michigan | 48910 | — |
| William Beaumont Hospital - Royal Oak Campus | Royal Oak | Michigan | 48073-6769 | — |
| St. Mary's - Duluth Clinic Cancer Center | Duluth | Minnesota | 55805 | — |
| Children's Hospitals and Clinics - Minneapolis/St. Paul | Minneapolis | Minnesota | 55404 | — |
| Mayo Clinic Cancer Center | Rochester | Minnesota | 55905 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216-4505 | — |
| Children's Mercy Hospital | Kansas City | Missouri | 64108 | — |
| Cardinal Glennon Children's Hospital | St Louis | Missouri | 63104 | — |
| St. Louis Children's Hospital | St Louis | Missouri | 63110 | — |
| CCOP - Montana Cancer Consortium | Billings | Montana | 59101 | — |
| Great Falls Clinic | Great Falls | Montana | 59405 | — |
| Sletten Regional Cancer Institute | Great Falls | Montana | 59405 | — |
| Children's Hospital of Omaha | Omaha | Nebraska | 68114 | — |
| UNMC Eppley Cancer Center at the University of Nebraska Medical Center | Omaha | Nebraska | 68198-2168 | — |
| Sunrise Hospital and Medical Center | Las Vegas | Nevada | 89109 | — |
| Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Cancer Center at Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| St. Barnabas Medical Center | Livingston | New Jersey | 07039 | — |
| Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School | New Brunswick | New Jersey | 08903 | — |
| Newark Beth Israel Medical Center | Newark | New Jersey | 07112-2094 | — |
| St. Joseph's Hospital and Medical Center | Paterson | New Jersey | 07503 | — |
| Valerie Fund Children's Center at Atlantic Health | Summit | New Jersey | 07901 | — |
| University of New Mexico Cancer Research and Treatment Center | Albuquerque | New Mexico | 87131 | — |
| Children's Hospital at Albany Medical Center | Albany | New York | 12208 | — |
| Brooklyn Hospital Center | Brooklyn | New York | 11201-5493 | — |
| SUNY Downstate Medical Center | Brooklyn | New York | 11203 | — |
| Brookdale University Hospital and Medical Center | Brooklyn | New York | 11212 | — |
| Comprehensive Cancer Center at Maimonides Medical Center | Brooklyn | New York | 11219 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263-0001 | — |
| Schneider Children's Hospital | New Hyde Park | New York | 11042 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10021 | — |
| New York Weill Cornell Cancer Center at Cornell University | New York | New York | 10021 | — |
| Mount Sinai Medical Center | New York | New York | 10029 | — |
| Herbert Irving Comprehensive Cancer Center at Columbia University | New York | New York | 10032 | — |
| James P. Wilmot Cancer Center at University of Rochester Medical Center | Rochester | New York | 14642 | — |
| Long Island Cancer Center at Stony Brook University Hospital | Stony Brook | New York | 11794-8174 | — |
| SUNY Upstate Medical University Hospital | Syracuse | New York | 13210 | — |
| Albert Einstein Cancer Center at Albert Einstein College of Medicine | The Bronx | New York | 10461 | — |
| New York Medical College | Valhalla | New York | 10595 | — |
| Mission Hospitals - Memorial Campus | Asheville | North Carolina | 28801 | — |
| Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| Blumenthal Cancer Center at Carolinas Medical Center | Charlotte | North Carolina | 28232-2861 | — |
| Presbyterian Cancer Center at Presbyterian Hospital | Charlotte | North Carolina | 28233 | — |
| Duke Comprehensive Cancer Center | Durham | North Carolina | 27710 | — |
| Leo W. Jenkins Cancer Center at Pitt County Memorial Hospital | Greenville | North Carolina | 27858-4354 | — |
| Dakota Cancer Institute at Innovis Health - Dakota Clinic | Fargo | North Dakota | 58103-4940 | — |
| Children's Hospital Medical Center of Akron | Akron | Ohio | 44308-1062 | — |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229-3039 | — |
| Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | 44195 | — |
| Columbus Children's Hospital | Columbus | Ohio | 43205-2696 | — |
| Children's Medical Center - Dayton | Dayton | Ohio | 45404 | — |
| Toledo Children's Hospital | Toledo | Ohio | 43601 | — |
| Tod Children's Hospital - Forum Health | Youngstown | Ohio | 44501 | — |
| Children's Hospital at Oklahoma University Medical Center | Oklahoma City | Oklahoma | 73104 | — |
| Natalie Warren Bryant Cancer Center at St. Francis Hospital | Tulsa | Oklahoma | 74136 | — |
| CCOP - Columbia River Oncology Program | Portland | Oregon | 97225 | — |
| Legacy Emanuel Hospital and Health Center & Children's Hospital | Portland | Oregon | 97227 | — |
| Doernbecher Children's Hospital at Oregon Health & Science University | Portland | Oregon | 97239-3098 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822-1320 | — |
| Penn State Children's Hospital | Hershey | Pennsylvania | 17033 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| St. Christopher's Hospital for Children | Philadelphia | Pennsylvania | 19134-1095 | — |
| Children's Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Hollings Cancer Center at Medical University of South Carolina | Charleston | South Carolina | 29425-0721 | — |
| Palmetto Health South Carolina Cancer Center | Columbia | South Carolina | 29203 | — |
| Children's Hospital of Greenville Hospital System | Greenville | South Carolina | 29605 | — |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57105-1080 | — |
| Sioux Valley Hospital and University of South Dakota Medical Center | Sioux Falls | South Dakota | 57117-5039 | — |
| East Tennessee State University Cancer Center at Johnson City Medical Center | Johnson City | Tennessee | 37614-0622 | — |
| East Tennessee Children's Hospital | Knoxville | Tennessee | 37901 | — |
| St. Jude Children's Research Hospital | Memphis | Tennessee | 38105 | — |
| Vanderbilt Children's Hospital | Nashville | Tennessee | 37232-6310 | — |
| Texas Tech University Health Sciences Center School of Medicine | Amarillo | Texas | 79106 | — |
| Medical City Dallas Hospital | Dallas | Texas | 75230 | — |
| Simmons Cancer Center at University of Texas Southwestern Medical Center at Dallas | Dallas | Texas | 75390-9063 | — |
| Brooke Army Medical Center | Fort Sam Houston | Texas | 78234 | — |
| Cook Children's Medical Center - Fort Worth | Fort Worth | Texas | 76104 | — |
| University of Texas Medical Branch | Galveston | Texas | 77555-0209 | — |
| M.D. Anderson Cancer Center at University of Texas | Houston | Texas | 77030-4009 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| San Antonio Military Pediatric Cancer and Blood Disorders Center | Lackland Air Force Base | Texas | 78236 | — |
| Wilford Hall Medical Center | Lackland Air Force Base | Texas | 78236 | — |
| Covenant Children's Hospital | Lubbock | Texas | 79410 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78207 | — |
| MBCCOP - South Texas Pediatrics | San Antonio | Texas | 78229-3900 | — |
| Methodist Cancer Center at Methodist Specialty and Transplant Hospital | San Antonio | Texas | 78229-3902 | — |
| CCOP - Scott and White Hospital | Temple | Texas | 76508 | — |
| Center for Cancer Prevention and Care at Scott and White Clinic | Temple | Texas | 76508 | — |
| Huntsman Cancer Institute at University of Utah | Salt Lake City | Utah | 84112 | — |
| Vermont Cancer Center at University of Vermont | Burlington | Vermont | 05401-3498 | — |
| Cancer Center at the University of Virginia | Charlottesville | Virginia | 22908 | — |
| INOVA Fairfax Hospital | Falls Church | Virginia | 22042-3300 | — |
| Children's Hospital of the King's Daughters | Norfolk | Virginia | 23507 | — |
| Naval Medical Center - Portsmouth | Portsmouth | Virginia | 23708-5100 | — |
| Massey Cancer Center at Virginia Commonwealth University | Richmond | Virginia | 23298-0212 | — |
| Carilion Medical Center for Children at Roanoke Community Hospital | Roanoke | Virginia | 24029 | — |
| St. Joseph Hospital Community Cancer Center | Bellingham | Washington | 98225 | — |
| Olympic Hematology and Oncology | Bremerton | Washington | 98310 | — |
| Cancer Care Center at Skagit Valley Hospital | Mount Vernon | Washington | 98273 | — |
| Harborview Medical Center | Seattle | Washington | 98104 | — |
| Children's Hospital and Regional Medical Center - Seattle | Seattle | Washington | 98105 | — |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109-1024 | — |
| Group Health Central Hospital | Seattle | Washington | 98112 | — |
| Swedish Cancer Institute at Swedish Medical Center - First Hill Campus | Seattle | Washington | 98114 | — |
| University Cancer Center at University of Washington Medical Center | Seattle | Washington | 98195 | — |
| Cancer Care Northwest - Spokane South | Spokane | Washington | 99202 | — |
| Deaconess Medical Center | Spokane | Washington | 99210-0248 | — |
| Madigan Army Medical Center | Tacoma | Washington | 98431-0001 | — |
| Central Washington Hospital | Wenatchee | Washington | 98801 | — |
| Wenatchee Valley Clinic | Wenatchee | Washington | 98801 | — |
| West Virginia University - Robert C. Byrd Health Sciences Center - Charleston Division | Charleston | West Virginia | 25302 | — |
| Cabell Huntington Hospital | Huntington | West Virginia | 25701 | — |
| Mary Babb Randolph Cancer Center at West Virginia University Hospitals | Morgantown | West Virginia | 26506-9300 | — |
| Bellin Memorial Hospital | Green Bay | Wisconsin | 54301 | — |
| CCOP - St. Vincent Hospital Cancer Center, Green Bay | Green Bay | Wisconsin | 54301 | — |
| St. Vincent Hospital | Green Bay | Wisconsin | 54307-9070 | — |
| Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical Center | La Crosse | Wisconsin | 54601 | — |
| Medical College of Ohio Cancer Institute | Madison | Wisconsin | 53792-6164 | — |
| University of Wisconsin Comprehensive Cancer Center | Madison | Wisconsin | 53792-6164 | — |
| Marshfield Clinic - Marshfield Center | Marshfield | Wisconsin | 54449-5772 | — |
| CCOP - Marshfield Clinic Research Foundation | Marshfield | Wisconsin | 54449 | — |
| Midwest Children's Cancer Center | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 27 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00006734, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 3, 2023 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00006734 live on ClinicalTrials.gov.