Does Gabapentin and Lamotriginel Have Significantly Fewer Side-effects While Providing Equal or Better Seizure Control Than the Current Drug Choice, Carbamazepine, for the Treatment of Seizures in the Elderly.
Public ClinicalTrials.gov record NCT00007670. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
CSP #428 - Treatment of Seizures in the Elderly Population
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
New onset epilepsy in the elderly occurs in 45,000-50,000 elderly patients each year. These patients are especially vulnerable to side effects from medications because of changes caused by the aging process and the fact that these patients often have many common diseases for which they are already receiving medications for so that the likelihood of drug interactions is increased. Two new drugs, gabapentin and lamotrigine, have recently been approved by the FDA as antiepileptic drugs. These drugs have demonstrated efficacy in the treatment of partial onset seizures, the most common seizures in the elderly. These new compounds also have favorable side effect profiles and infrequent drug-drug interactions and, therefore, would be expected to be well-tolerated in the elderly.
Study identification
- NCT ID
- NCT00007670
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 720 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 60 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 31, 1997
- Primary completion
- Not listed
- Completion
- Feb 28, 2003
- Last update posted
- Oct 29, 2023
1998 – 2003
United States locations
- U.S. sites
- 20
- U.S. states
- 13
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Birmingham VA Medical Center | Birmingham | Alabama | 35233 | — |
| Carl T. Hayden VA Medical Center | Phoenix | Arizona | 85012 | — |
| Vamc - West Los Angeles, Los Angeles, Ca | Los Angeles | California | 90073 | — |
| Vamc - San Diego, San Diego, Ca | San Diego | California | 92161 | — |
| San Francisco VAMC | San Francisco | California | 94121 | — |
| Denver VA Medical Center | Denver | Colorado | 80220 | — |
| Vamc - Bay Pines, Fl | Bay Pines | Florida | 33744 | — |
| Gainesville VA Medical Center | Gainesville | Florida | 32608-1197 | — |
| Miami VA Medical Center | Miami | Florida | 33125 | — |
| Study Chairperson | Miami | Florida | 33125 | — |
| Chicago VA Medical Center (West Side) | Chicago | Illinois | 60612 | — |
| Edward Hines Jr. VA Hospital | Hines | Illinois | 60141 | — |
| New Orleans VAMC | New Orleans | Louisiana | 70112 | — |
| Boston VA Medical Center | Boston | Massachusetts | 02130 | — |
| Bronx VA Medical Center | The Bronx | New York | 10468 | — |
| Study Chairman | The Bronx | New York | 10468 | — |
| Oklahoma City VA Medical Center | Oklahoma City | Oklahoma | 73104 | — |
| Vamc - Pittsburgh, Pittsburgh, Pa | Pittsburgh | Pennsylvania | 15240-1001 | — |
| Dallas VA Medical Center | Dallas | Texas | 75216 | — |
| Hunter Holmes McGuire VA Medical Center | Richmond | Virginia | 23249 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00007670, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 29, 2023 · Synced Sep 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00007670 live on ClinicalTrials.gov.