Nolatrexed Dihydrochloride Compared With Doxorubicin in Treating Patients With Recurrent or Unresectable Liver Cancer
Public ClinicalTrials.gov record NCT00012324. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Randomized Controlled Study Comparing the Survival of Patients With Unresectable Hepatocellular Carcinoma (HCC) Treated With THYMITAQ to Patients Treated With Doxorubicin
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which chemotherapy regimen is more effective for liver cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of two different chemotherapy regimens in treating patients who have recurrent or unresectable liver cancer.
Study identification
- NCT ID
- NCT00012324
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- Not listed
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 31, 2000
- Primary completion
- Not listed
- Completion
- Oct 31, 2005
- Last update posted
- Jun 25, 2013
2000 – 2005
United States locations
- U.S. sites
- 38
- U.S. states
- 21
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Clinical Research Center, Incorporated | Tucson | Arizona | 85715 | — |
| Arkansas Cancer Research Center at University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Tower Cancer Research Foundation | Beverly Hills | California | 90211 | — |
| Scripps Cancer Center at Scripps Clinic | La Jolla | California | 92037 | — |
| David and Donna Long Center for Cancer Treatment at Sharp Grossmont Hospital | La Mesa | California | 91942 | — |
| Veterans Affairs Medical Center - Long Beach | Long Beach | California | 90822 | — |
| California Pacific Medical Center - Pacific Campus | San Francisco | California | 94115 | — |
| Olive View - UCLA Medical Center Foundation | Sylmar | California | 91342 | — |
| California Hematology/Oncology Medical Group | Torrance | California | 90505 | — |
| Helen F. Graham Cancer Center | Newark | Delaware | 19713 | — |
| Lombardi Cancer Center at Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007 | — |
| Florida Cancer Institute - Bayonet Point | Hudson | Florida | 34667 | — |
| University of Miami Sylvester Comprehensive Cancer Center | Miami | Florida | 33136 | — |
| Oncology-Hematology Group of South Florida, P.A. | Miami | Florida | 33176 | — |
| Ocala Research Institute, Incorporated | Ocala | Florida | 34480 | — |
| Cancer Research Center of Hawaii | Honolulu | Hawaii | 96813 | — |
| Robert H. Lurie Comprehensive Cancer Center at Northwestern University | Chicago | Illinois | 60611 | — |
| University of Illinois at Chicago Cancer Center | Chicago | Illinois | 60612 | — |
| Holden Comprehensive Cancer Center at University of Iowa | Iowa City | Iowa | 52242-1009 | — |
| Louisiana Oncology Associates - Lafayette | Lafayette | Louisiana | 70506 | — |
| Stanley S. Scott Cancer Center at Louisiana State University Medical Center - New Orleans | New Orleans | Louisiana | 70112 | — |
| Alvin and Lois Lapidus Cancer Institute at Sinai Hospital | Baltimore | Maryland | 21215 | — |
| University of Minnesota Cancer Center | Minneapolis | Minnesota | 55455 | — |
| Saint Louis University Cancer Center | St Louis | Missouri | 63110 | — |
| Siteman Cancer Center at Barnes-Jewish Hospital | St Louis | Missouri | 63110 | — |
| UNMC Eppley Cancer Center at the University of Nebraska Medical Center | Omaha | Nebraska | 68198-7680 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Veterans Affairs Medical Center - Albuquerque | Albuquerque | New Mexico | 87108 | — |
| New York Weill Cornell Cancer Center at Cornell University | New York | New York | 10021 | — |
| Herbert Irving Comprehensive Cancer Center at Columbia University | New York | New York | 10032 | — |
| SUNY Upstate Medical University Hospital | Syracuse | New York | 13210 | — |
| Albert Einstein Cancer Center at Albert Einstein College of Medicine | The Bronx | New York | 10467 | — |
| New York Medical College | Valhalla | New York | 10595 | — |
| Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | 44111 | — |
| Albert Einstein Cancer Center | Philadelphia | Pennsylvania | 19141 | — |
| Cancer Centers of the Carolinas - Eastside | Greenville | South Carolina | 29615 | — |
| Medical City Dallas Hospital | Dallas | Texas | 75230 | — |
| Joe Arrington Cancer Research and Treatment Center | Lubbock | Texas | 79410-1894 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00012324, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 25, 2013 · Synced Sep 16, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00012324 live on ClinicalTrials.gov.