ClinicalTrials.gov record
Irinotecan With or Without Oxaliplatin in Treating Patients With Metastatic Colorectal Cancer
ClinicalTrials.gov ID: NCT00012389
Public ClinicalTrials.gov record NCT00012389. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Open-Label, Randomized, Two-Arm Study of Irinotecan (CPT-11) Versus the Combination of Oxaliplatin + Irinotecan (CPT-11) as Second-Line Treatment of Metastatic Colorectal Carcinoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if irinotecan is more effective with or without oxaliplatin in treating metastatic colorectal cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of irinotecan with or without oxaliplatin in treating patients who have metastatic colorectal cancer.
Study identification
- NCT ID
- NCT00012389
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- Not listed
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2000 (Type not available)
- Primary completion
- Not listed
- Completion
- Oct 2008 (Actual)
- Last update posted
- Dec 19, 2013
2000 – 2008
United States locations
- U.S. sites
- 100
- U.S. states
- 34
- U.S. cities
- 86
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Comprehensive Cancer Institute of Huntsville | Huntsville | Alabama | 35801 | — |
| Oncology Center at Providence Park | Mobile | Alabama | 36688 | — |
| Arizona Clinical Research Center | Tucson | Arizona | 85712 | — |
| Citrus Valley Medical Center | Covina | California | 91722 | — |
| California Cancer Care, Inc. | Greenbrae | California | 94904-2007 | — |
| Tower Hematology Oncology Medical Group | Los Angeles | California | 90048 | — |
| Kenmar Research Institute | Los Angeles | California | 90057 | — |
| Not listed | Los Angeles | California | 90067 | — |
| Medical Oncology Care Associates | Orange | California | 92868 | — |
| P.M.K. Medical Group, Inc. | Oxnard | California | 93030 | — |
| Cancer and Blood Institute of the Desert | Rancho Mirage | California | 92270 | — |
| Kaiser Permanente-Southern California Permanente Medical Group | San Diego | California | 92120 | — |
| John Wayne Cancer Institute | Santa Monica | California | 90404 | — |
| Kaiser Permanente Medical Center - Vallejo | Vallejo | California | 94589 | — |
| Colorado Permanente Medical Group, P.C. | Denver | Colorado | 80205 | — |
| Rocky Mountain Cancer Center | Denver | Colorado | 80218 | — |
| University of Colorado Cancer Center | Denver | Colorado | 80220 | — |
| Whittingham Cancer Center | Norwalk | Connecticut | 06856 | — |
| George Washington University Medical Center | Washington D.C. | District of Columbia | 20037 | — |
| Comprehensive Cancer Care Specialists of Boca Raton | Boca Raton | Florida | 33428 | — |
| Center for Hematology-Oncology | Boca Raton | Florida | 33486 | — |
| Southeast Florida Hematology-Oncology Group | Fort Lauderdale | Florida | 33308 | — |
| Florida Cancer Specialists | Fort Myers | Florida | 33901 | — |
| Shands Hospital and Clinics, University of Florida | Gainesville | Florida | 32610-100277 | — |
| Hematology and Oncology Associates of Jacksonville | Jacksonville | Florida | 32207 | — |
| University of Florida Health Science Center - Jacksonville | Jacksonville | Florida | 32209 | — |
| Lakeland Regional Medical Center | Lakeland | Florida | 33804 | — |
| Lake Heart and Cancer Medical Center | Leesburg | Florida | 34748 | — |
| Oncology-Hematology Group of South Florida | Miami | Florida | 33176 | — |
| Hematology and Oncology Consultants, P.A. | Orlando | Florida | 32804 | — |
| Hematology/Oncology Associates | Port Saint Lucie | Florida | 34952 | — |
| Oncology & Hematology Associates of West Broward | Tamarac | Florida | 33321 | — |
| University Community Hospital | Tampa | Florida | 33613 | — |
| Hematology and Oncology Consultants | Titusville | Florida | 32796 | — |
| North Idaho Cancer Center | Coeur d'Alene | Idaho | 83814 | — |
| Northwest Medical Specialists, P.C. | Arlington Heights | Illinois | 60004 | — |
| Dreyer Medical Clinic | Aurora | Illinois | 60506 | — |
| Northwestern Medical Faculty Foundation | Chicago | Illinois | 60611 | — |
| Cancer Care Center | New Albany | Indiana | 47150 | — |
| Albert B. Chandler Medical Center, University of Kentucky | Lexington | Kentucky | 40536-0084 | — |
| James Graham Brown Cancer Center | Louisville | Kentucky | 40202 | — |
| Kentuckiana Cancer Institute | Louisville | Kentucky | 40202 | — |
| Norton Healthcare Pavilion | Louisville | Kentucky | 40202 | — |
| Veterans Affairs Medical Center - Louisville | Louisville | Kentucky | 40206 | — |
| Baton Rouge General Medical Center | Baton Rouge | Louisiana | 70806 | — |
| Louisiana Oncology Associates | Lafayette | Louisiana | 70506 | — |
| Doctors Hospital of Jefferson | Metairie | Louisiana | 70006 | — |
| Stanley Scott Cancer Center | New Orleans | Louisiana | 70112 | — |
| Greater Baltimore Medical Center and Cancer Center | Baltimore | Maryland | 21204 | — |
| Medical Center of Boston | Boston | Massachusetts | 02120 | — |
| Berkshire Hematology Oncology, P.C. | Pittsfield | Massachusetts | 01201 | — |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201-1379 | — |
| Not listed | Flint | Michigan | 48532 | — |
| Parker Hughes Cancer Center | Roseville | Minnesota | 55113 | — |
| Jackson Oncology Associates, PLLC | Jackson | Mississippi | 39202 | — |
| Veterans Affairs Medical Center - Kansas City | Kansas City | Missouri | 64128 | — |
| Missouri Cancer Care, P.C. | Saint Charles | Missouri | 63301 | — |
| Siteman Cancer Center | St Louis | Missouri | 63110 | — |
| St. John's Mercy Medical Center | St Louis | Missouri | 63141 | — |
| Great Falls Clinic | Great Falls | Montana | 59405 | — |
| Western Montana Clinic | Missoula | Montana | 59807-7609 | — |
| Somerset Medical Center | Somerville | New Jersey | 08876 | — |
| Cooper Cancer Institute | Voorhees Township | New Jersey | 08043 | — |
| Veterans Affairs Medical Center - Albany | Albany | New York | 12208 | — |
| Queens Medical Associates, PC | Fresh Meadows | New York | 11365 | — |
| Queens Hospital Center | Jamaica | New York | 11432 | — |
| Interlakes Oncology/Hematology PC | Rochester | New York | 14623 | — |
| Montefiore Medical Center | The Bronx | New York | 10467-2490 | — |
| New York Medical College | Valhalla | New York | 10595 | — |
| Lineberger Comprehensive Cancer Center, UNC | Chapel Hill | North Carolina | 27599-7295 | — |
| Raleigh Hematology/Oncology Associates - Wake Practice | Raleigh | North Carolina | 27609 | — |
| Piedmont Hematology-Oncology Associates | Winston-Salem | North Carolina | 27103 | — |
| Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | 44195 | — |
| Hematology Oncology Consultants Inc | Columbus | Ohio | 43235 | — |
| Bend Memorial Clinic | Bend | Oregon | 97701 | — |
| Kaiser Permanente - Portland | Portland | Oregon | 97227 | — |
| Pinnacle Health Hospitals | Harrisburg | Pennsylvania | 17105-8700 | — |
| Abington Hematology Oncology Associates, Incorporated | Meadowbrook | Pennsylvania | 18974 | — |
| University of Pennsylvania Cancer Center | Philadelphia | Pennsylvania | 19104 | — |
| Pennsylvania Oncology Hematology Associates | Philadelphia | Pennsylvania | 19106 | — |
| University of Pittsburgh Cancer Institute | Pittsburgh | Pennsylvania | 15213 | — |
| Lifespan: The Miriam Hospital | Providence | Rhode Island | 02906 | — |
| Physicians East - Quadrangle | Greenville | South Carolina | 27834 | — |
| Cancer Centers of the Carolinas | Greenville | South Carolina | 29615 | — |
| Erlanger Health Systems | Chattanooga | Tennessee | 37403 | — |
| Baptist Regional Cancer Center - Knoxville | Knoxville | Tennessee | 37901 | — |
| West Clinic | Memphis | Tennessee | 38117 | — |
| Memphis Cancer Center | Memphis | Tennessee | 38119 | — |
| Tennessee Oncology, P.L.L.C. | Nashville | Tennessee | 37205 | — |
| Vanderbilt-Ingram Cancer Center | Nashville | Tennessee | 37232-6307 | — |
| Lone Star Oncology | Austin | Texas | 78759 | — |
| Center for Oncology Research and Treatment, Medical City Hospital | Dallas | Texas | 75230 | — |
| Baptist Health System Cancer Program | San Antonio | Texas | 78205 | — |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | — |
| Cancer Center at the University of Virginia | Charlottesville | Virginia | 22908 | — |
| Hematology-Oncology Associates of Frederiksburg, Inc. | Fredericksburg | Virginia | 22401 | — |
| Virginia Mason Medical Center | Seattle | Washington | 98101 | — |
| Advanced Health Care | Milwaukee | Wisconsin | 53209 | — |
| UW Cancer Center Wausau Hospital | Wausau | Wisconsin | 54401 | — |
| Irving Cancer Center | Laramie | Wyoming | 82070 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 54 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00012389, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 19, 2013 · Synced Oct 11, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00012389 live on ClinicalTrials.gov.