CATIE- Schizophrenia Trial
Public ClinicalTrials.gov record NCT00014001. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Comparative Effectiveness of Antipsychotic Medications in Patients With Schizophrenia (CATIE Schizophrenia Trial)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The CATIE Schizophrenia Trial is part of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Project. The schizophrenia trial is being conducted to determine the long-term effects and usefulness of antipsychotic medications in persons with schizophrenia. It is designed for people with schizophrenia who may benefit from a medication change. The study involves the newer atypical antipsychotics (olanzapine, quetiapine, risperidone, clozapine, and ziprasidone)and the typical antipsychotics (perphenazine and fluphenazine decanoate). All participants will receive an initial comprehensive medical and psychiatric evaluation and will be closely followed throughout the study. For most participants the study will last up to 18 months. Everyone in the study will be offered an educational program about schizophrenia and family members will be encouraged to participate.
Study identification
- NCT ID
- NCT00014001
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 1,600 participants
Conditions and interventions
Conditions
Interventions
- perphenazine Drug
- olanzapine Drug
- quetiapine Drug
- risperidone Drug
- ziprasidone Drug
- clozapine Drug
- fluphenazine decanoate Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2000 (Type not available)
- Primary completion
- Not listed
- Completion
- Dec 2004 (Type not available)
- Last update posted
- Jun 17, 2015
2000 – 2004
United States locations
- U.S. sites
- 54
- U.S. states
- 24
- U.S. cities
- 48
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Synergy Clinical Research | Chula Vista | California | 91910 | — |
| LA County-University of Southern California Medical Center | Los Angeles | California | 90033 | — |
| University of California, Irvine | Orange | California | 92868 | — |
| University of California,San Diego/VA Medical System | San Diego | California | 92161 | — |
| Stanford University School of Medicine | Stanford | California | 94305 | — |
| Harbor UCLA Research & Education Institute | Torrance | California | 90502 | — |
| New Britain General Hospital | New Britain | Connecticut | 06050 | — |
| Yale University/Connecticut Mental Health Center | New Haven | Connecticut | 06519 | — |
| Mental Health Advocates Inc. | Boca Raton | Florida | 33432 | — |
| VA Medical Center | Miami | Florida | 33125 | — |
| University of Miami School of Medicine | Miami | Florida | 33316 | — |
| Emory University School of Medicine | Atlanta | Georgia | 30319 | — |
| The Queen's Medical Center | Honolulu | Hawaii | 96813 | — |
| Northwestern Medical School Department of Psychiatry | Chicago | Illinois | 60634 | — |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62702 | — |
| University of Iowa Hospital | Iowa City | Iowa | 52242 | — |
| Psychiatric Research Institute, Outpatient Clinic | Wichita | Kansas | 67214 | — |
| Louisiana State University Health Services Center | Shreveport | Louisiana | 71130 | — |
| Clinical Insights, Inc. | Glen Burnie | Maryland | 21061 | — |
| Massachusetts General Hospital-Freedom Trial Clinic Schizophrenia Program | Boston | Massachusetts | 02114 | — |
| St. Elizabeth's Medical Center | Boston | Massachusetts | 02135 | — |
| Corrigan Mental Health Center | Fall River | Massachusetts | 02720 | — |
| University Of Massachusetts Memorial Health Care | Worcester | Massachusetts | 01605 | — |
| University of Minnesota School of Medicine | Minneapolis | Minnesota | 55454 | — |
| University of Mississippi VA Medical Center | Jackson | Mississippi | 39216 | — |
| University of Missouri Kansas City Medical School | Kansas City | Missouri | 64108 | — |
| Burrell Behavioral Health-Cox North Hospital | Springfield | Missouri | 65802 | — |
| Washington University School of Medicine | St Louis | Missouri | 63112 | — |
| Albuquerque VA Medical Center | Albuquerque | New Mexico | 87124 | — |
| SUNY Downstate Medical Center | Brooklyn | New York | 11203 | — |
| Mount Sinai Medical Center | New York | New York | 10029 | — |
| University of Rochester Medical Center | Rochester | New York | 14620 | — |
| Staten Island University Hospital | Staten Island | New York | 10305 | — |
| Mount Sinai Medical Center-Bronx VA Medical Center | The Bronx | New York | 10468 | — |
| Duke University Medical Center-John Umstead Hospital | Butner | North Carolina | 27509 | — |
| University of North Carolina School of Medicine | Chapel Hill | North Carolina | 27599 | — |
| Behavioral Health Center | Charlotte | North Carolina | 28203 | — |
| Dorothea Dix Hospital | Raleigh | North Carolina | 27603 | — |
| Appalachian Psychiatric Healthcare System | Athens | Ohio | 45701 | — |
| North East Ohio Health Services | Beachwood | Ohio | 44122 | — |
| Philadelphia VA Medical Center | Philadelphia | Pennsylvania | 19104 | — |
| Eastern Pennsylvania Psychiatric Institute | Philadelphia | Pennsylvania | 19129 | — |
| Belmont Center for Comprehensive Treatment | Philadelphia | Pennsylvania | 19131 | — |
| Veterans Affairs Medical Center | Charleston | South Carolina | 29401 | — |
| Vanderbilt University Schizophrenia Research | Nashville | Tennessee | 37212 | — |
| Tri-County MHMR Services | Conroe | Texas | 77304 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Life Management Center for MH/MR Services | El Paso | Texas | 98493 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| MHMRA of Harris County-Northwest Community Service Center | Houston | Texas | 77092 | — |
| The Center for Health Care Services | San Antonio | Texas | 78208 | — |
| Valley Mental Health Psychopharmacology Research Center | Salt Lake City | Utah | 84117 | — |
| University of Utah Medical Center | Salt Lake City | Utah | 84132 | — |
| VA Puget Sound Health Care System | Tacoma | Washington | 98493 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00014001, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 17, 2015 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00014001 live on ClinicalTrials.gov.