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Completed Phase 3 Interventional Results available

Combination Chemotherapy With or Without Colony-stimulating Factors in Treating Women With Breast Cancer

ClinicalTrials.gov ID: NCT00014222

Public ClinicalTrials.gov record NCT00014222. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 22, 2026, 11:17 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III Adjuvant Trial Of Sequenced EC + Filgrastim + Epoetin Alfa Followed By Paclitaxel Versus Sequenced AC Followed By Paclitaxel Versus CEF As Therapy For Premenopausal Women And Early Postmenopausal Women Who Have Had Potentially Curative Surgery For Node Positive Or High Risk Node Negative Breast Cancer

Study identification

NCT ID
NCT00014222
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
NCIC Clinical Trials Group
Network
Enrollment
2,104 participants

Conditions and interventions

Conditions

Interventions

  • cyclophosphamide Drug
  • doxorubicin hydrochloride Drug
  • epirubicin hydrochloride Drug
  • epoetin alfa Biological
  • filgrastim Biological
  • fluorouracil Drug
  • paclitaxel Drug

Drug · Biological

Eligibility (public fields only)

Age range
Up to 60 Years
Sex
Female
Healthy volunteers
Not listed

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 3, 2000
Primary completion
Feb 9, 2014
Completion
Mar 16, 2014
Last update posted
Oct 4, 2020

2000 – 2014

United States locations

U.S. sites
44
U.S. states
25
U.S. cities
42
Facility City State ZIP Site status
Sparks-Arkansas Oklahoma Cancer Treatment Centre Fort Smith Arkansas 72901
Hematology Oncology Services of Arkansas Little Rock Arkansas 72205
Scripps Cancer Center La Jolla California 92037
University of Colorado Cancer Centre Aurora Colorado 80010-0510
Greenwich Hospital - Bendheim Cancer Center Greenwich Connecticut 06830
Sibley Memorial Hospital, Oncology Research Washington D.C. District of Columbia 20016
Comprehensive Cancer Care Centre at Boca Raton Boca Raton Florida 33428
University of Florida Gainesville Florida 32610-0277
Florida Oncology Associates Orange Park Florida 32073
The University of Chicago Medical Center Chicago Illinois 60637-1470
Therapy Associates, Inc., Hematology/Oncology Evansville Indiana 47715
Lexington Oncology Assts./Central Baptist Hospital Lexington Kentucky 40503
Consultants in Blood Disorders and Cancer Louisville Kentucky 40207
CHRISTUS Schumpert Medical Center - Hem/Onc Clinic Shreveport Louisiana 71101
Willis-Knighton Cancer Center Shreveport Louisiana 71103-3
Maine Center for Cancer Medicine and Blood Disorders Scarborough Maine 04074-9308
Maine General Medical Center Waterville Maine 04901
Suburban Hospital Cancer Program Bethesda Maryland 20817
Associates in Oncology/Hematology Rockville Maryland 20850
Saint Joseph Medical Center, Cancer Care Program Towson Maryland 21204
Baystate Regional Cancer Program Springfield Massachusetts 01107
St. Luke's Cancer Care Centre Duluth Minnesota 55802
University of Minnesota Cancer Centre Minneapolis Minnesota 55455
Columbia-Capitol Comprehensive Care Clinics Jefferson City Missouri 65109
Saint Louis University Hospital St Louis Missouri 63110-0250
Nebraska Methodist Hospital Omaha Nebraska 68114
Creighton University Cancer Centre Omaha Nebraska 68131
Advanced Oncology Associates Armonk New York 10504
Queens Medical Associates, PC Fresh Meadows New York 11366
Winthrop University Hospital Onc/Hem Mineola New York 11501
Hematology Oncol. Associates Rockland Nyack New York 10960
University of Rochester Rochester New York 14642
Staten Island University Hospital Staten Island New York 10305
Our Lady of Mercy Medical Center The Bronx New York 10466
Duke University Medical Center Durham North Carolina 27710
ECU School of Medicine, Leo Jenkins Cancer Center Greenville North Carolina 27858
Oncology/Hematology Care, Inc. Cincinnati Ohio 45242
Pottstown Memorial Regional Cancer Centre Pottstown Pennsylvania 19464
Santee Hematology Oncology Sumter South Carolina 29150
University Oncology and Hematology Associates Chattanooga Tennessee 37404
Lone Star Oncology Consultants, PA Austin Texas 78759
Center for Oncology Research and Treatment Dallas Texas 75230
Northern Utah Associates Ogden Utah 84403
Arlington-Fairfax Hematology Oncology P.C. Arlington Virginia 22205

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 34 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00014222, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 4, 2020 · Synced Apr 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00014222 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →