Depo-Medroxyprogesterone Acetate (DMPA, Depo-Provera) Use With Certain Anti-HIV Drugs in HIV-Infected Women
Public ClinicalTrials.gov record NCT00016601. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label, Non-Randomized Study of Pharmacokinetic Interactions Between Depo-Medroxyprogesterone Acetate (DMPA, Depo-Provera) and Selected Protease Inhibitor (PI) and Nonnucleoside Reverse Transcriptase Inhibitor (NNRTI) Therapies Among HIV-Infected Women
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to look at the level of depo-medroxyprogesterone acetate (DMPA or Depo-Provera) in the blood to see if is affected by certain anti-HIV drugs (nelfinavir \[NFV\], efavirenz \[EFV\], indinavir \[IDV\] in combination with ritonavir \[RTV\], and nevirapine \[NVP\]). This study will also look at the levels of these anti-HIV drugs to see if they are affected by DMPA. DMPA is a hormonal birth control method that is given as an injection. It is not known if taking DMPA together with anti-HIV drugs changes the amount of DMPA and/or the amount of anti-HIV drugs in the blood. If higher levels of DMPA occur, side effects may increase. If lower levels of anti-HIV drugs occur, the drugs may become less effective against HIV. This study will look at the levels of anti-HIV drugs and DMPA in the blood when these medications are used together.
Study identification
- NCT ID
- NCT00016601
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 76 participants
Conditions and interventions
Conditions
Interventions
- Indinavir sulfate Drug
- Ritonavir Drug
- Nelfinavir mesylate Drug
- Efavirenz Drug
- Nevirapine Drug
- Medroxyprogesterone acetate Drug
Drug
Eligibility (public fields only)
- Age range
- 13 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2001 (Type not available)
- Primary completion
- Not listed
- Completion
- May 2004 (Actual)
- Last update posted
- Nov 2, 2012
2001 – 2004
United States locations
- U.S. sites
- 31
- U.S. states
- 16
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Univ of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Univ of Southern California / LA County USC Med Ctr | Los Angeles | California | 900331079 | — |
| Los Angeles County - USC Med Ctr | Los Angeles | California | 90033 | — |
| Children's Hosp of Denver | Denver | Colorado | 802181088 | — |
| Univ of Florida Health Science Ctr / Pediatrics | Jacksonville | Florida | 32209 | — |
| Univ of Miami (Pediatric) | Miami | Florida | 33161 | — |
| Mt Sinai Hosp Med Ctr / Dept of Pediatrics | Chicago | Illinois | 60608 | — |
| Univ of Illinois College of Medicine / Pediatrics | Chicago | Illinois | 60612 | — |
| Chicago Childrens Memorial Hosp (Pediatric) | Chicago | Illinois | 60614-3394 | — |
| The Univ of Chicago Childrens Hosp | Chicago | Illinois | 60637 | — |
| Indiana Univ Hosp | Indianapolis | Indiana | 46202-5250 | — |
| Methodist Hosp of Indiana / Life Care Clinic | Indianapolis | Indiana | 46202 | — |
| Wishard Hosp | Indianapolis | Indiana | 46202 | — |
| Tulane Univ / Charity Hosp of New Orleans | New Orleans | Louisiana | 701122699 | — |
| Univ of Maryland, Institute of Human Virology | Baltimore | Maryland | 21201 | — |
| Boston Med Ctr (Pediatric) | Boston | Massachusetts | 02118 | — |
| Children's Hosp of Michigan | Detroit | Michigan | 48201 | — |
| Beth Israel Med Ctr | New York | New York | 10003 | — |
| Columbia Presbyterian Med Ctr | New York | New York | 10032 | — |
| Community Health Network, Inc | Rochester | New York | 14642-0001 | — |
| St Mary's Hosp (Univ of Rochester/Infectious Diseases) | Rochester | New York | 14642 | — |
| Univ of Rochester Medical Center | Rochester | New York | 14642 | — |
| SUNY Health Sciences Ctr at Syracuse / Pediatrics | Syracuse | New York | 13210 | — |
| Univ of North Carolina | Chapel Hill | North Carolina | 27514 | — |
| Univ of Cincinnati | Cincinnati | Ohio | 452670405 | — |
| Case Western Reserve Univ | Cleveland | Ohio | 44106-5083 | — |
| MetroHealth Med Ctr | Cleveland | Ohio | 44109-1998 | — |
| Univ of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Univ of Texas Galveston | Galveston | Texas | 775550435 | — |
| Univ of Washington | Seattle | Washington | 98104 | — |
| Children's Hospital & Medical Center / Seattle ACTU | Seattle | Washington | 981050371 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00016601, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 2, 2012 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00016601 live on ClinicalTrials.gov.